Hepatitis C virus quantification in serum and saliva of HCV-infected patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Memórias do Instituto Oswaldo Cruz |
| Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000500016 |
Resumo: | The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV. |
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Hepatitis C virus quantification in serum and saliva of HCV-infected patientsHCVHCV transmissionserum HCV loadsalivary HCV loadThe hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV.Instituto Oswaldo Cruz, Ministério da Saúde2012-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000500016Memórias do Instituto Oswaldo Cruz v.107 n.5 2012reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762012000500016info:eu-repo/semantics/openAccessMenezes,Gisele Barreto LopesPereira,Fernanda AlbuquerqueDuarte,César Augusto BarrosCarmo,Theomira Mauadie AzevedoSilva Filho,Hermes Pedreira daZarife,Maria AliceKrieger,Marco AurélioReis,Eliana Almeida GomesReis,Mitermayer Geng2020-04-25T17:51:15Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:18:26.868Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
| dc.title.none.fl_str_mv |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| spellingShingle |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients Menezes,Gisele Barreto Lopes HCV HCV transmission serum HCV load salivary HCV load |
| title_short |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_full |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_fullStr |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_full_unstemmed |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_sort |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| author |
Menezes,Gisele Barreto Lopes |
| author_facet |
Menezes,Gisele Barreto Lopes Pereira,Fernanda Albuquerque Duarte,César Augusto Barros Carmo,Theomira Mauadie Azevedo Silva Filho,Hermes Pedreira da Zarife,Maria Alice Krieger,Marco Aurélio Reis,Eliana Almeida Gomes Reis,Mitermayer G |
| author_role |
author |
| author2 |
Pereira,Fernanda Albuquerque Duarte,César Augusto Barros Carmo,Theomira Mauadie Azevedo Silva Filho,Hermes Pedreira da Zarife,Maria Alice Krieger,Marco Aurélio Reis,Eliana Almeida Gomes Reis,Mitermayer G |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Menezes,Gisele Barreto Lopes Pereira,Fernanda Albuquerque Duarte,César Augusto Barros Carmo,Theomira Mauadie Azevedo Silva Filho,Hermes Pedreira da Zarife,Maria Alice Krieger,Marco Aurélio Reis,Eliana Almeida Gomes Reis,Mitermayer G |
| dc.subject.por.fl_str_mv |
HCV HCV transmission serum HCV load salivary HCV load |
| topic |
HCV HCV transmission serum HCV load salivary HCV load |
| dc.description.none.fl_txt_mv |
The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV. |
| description |
The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV. |
| publishDate |
2012 |
| dc.date.none.fl_str_mv |
2012-08-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000500016 |
| url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000500016 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/S0074-02762012000500016 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
text/html |
| dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.107 n.5 2012 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz |
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Memórias do Instituto Oswaldo Cruz |
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Fundação Oswaldo Cruz |
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FIOCRUZ |
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FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
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