Hepatitis C virus quantification in serum and saliva of HCV-infected patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/7492 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil. |
| id |
CRUZ_e9e98fccba8a83d1e8e5e6775e5b7a5b |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/7492 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Menezes, Gisele Barreto LopesPereira, Fernanda AlbuquerqueDuarte, César Augusto BarrosCarmo, Theomira Mauadie de AzevedoSilva Filho, Hermes Pedreira daZarife, Maria Alice Sant’AnnaKrieger, Marco AurélioReis, Eliana Almeida GomesReis, Mitermayer Galvão dos2014-04-03T18:30:47Z2014-04-03T18:30:47Z2012MENEZES, Gisele Barreto Lopes et al. Hepatitis C virus quantification in serum and saliva of HCV-infected patients. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 107, n. 5, p. 680-683, 2012.1678-8060https://www.arca.fiocruz.br/handle/icict/749210.1590/S0074-02762012000500016engFiocruzHepatitis C virus quantification in serum and saliva of HCV-infected patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.undação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil.undação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil.Laboratório Central de Saúde Pública Prof. Gonçalo Moniz. Salvador, BA, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil.The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this study. The HCV viral loads were determined through quantitative real-time polymerase chain reactions. The median viral RNA levels were 5.78 log10 copies in the serum and 3.32 log10 copies in the saliva. We observed that the salivary HCV viral load was significantly lower than the viral load in the serum. Further studies are required to understand the role of saliva in the diagnosis, management and potential transmission of HCV.HCVHCV transmissionSerum HCV loadSalivary HCV loadHepacivirus/isolamento & purificaçãoHepatite C Crônica/virologiaSaliva/virologiaSoro/virologiaAdultoEstudos de Casos e ControlesEstudos TransversaisFemininoGenótipoHepatite C Crônica/sangueHumanosMasculinoMeia-IdadeRNA Viral/análiseReação em Cadeia da Polimerase em Tempo RealCarga ViralAdulto Joveminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALGisele BLM Hepatitis C virus....pdfGisele BLM Hepatitis C virus....pdfapplication/pdf281896https://www.arca.fiocruz.br/bitstream/icict/7492/1/Gisele%20BLM%20Hepatitis%20C%20virus....pdf573458d786627c154593ecd239b68a76MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7492/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTGisele BLM Hepatitis C virus....pdf.txtGisele BLM Hepatitis C virus....pdf.txtExtracted texttext/plain22206https://www.arca.fiocruz.br/bitstream/icict/7492/5/Gisele%20BLM%20Hepatitis%20C%20virus....pdf.txt4f7086ae60ff7520e1208cad3dc458a5MD55THUMBNAILGisele BLM Hepatitis C virus....pdf.jpgGisele BLM Hepatitis C virus....pdf.jpgGenerated Thumbnailimage/jpeg2304https://www.arca.fiocruz.br/bitstream/icict/7492/4/Gisele%20BLM%20Hepatitis%20C%20virus....pdf.jpgeceb0c74334631db7627e86844311d67MD54icict/74922023-03-15 14:33:11.665oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:11Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| spellingShingle |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients Menezes, Gisele Barreto Lopes HCV HCV transmission Serum HCV load Salivary HCV load Hepacivirus/isolamento & purificação Hepatite C Crônica/virologia Saliva/virologia Soro/virologia Adulto Estudos de Casos e Controles Estudos Transversais Feminino Genótipo Hepatite C Crônica/sangue Humanos Masculino Meia-Idade RNA Viral/análise Reação em Cadeia da Polimerase em Tempo Real Carga Viral Adulto Jovem |
| title_short |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_full |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_fullStr |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_full_unstemmed |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| title_sort |
Hepatitis C virus quantification in serum and saliva of HCV-infected patients |
| author |
Menezes, Gisele Barreto Lopes |
| author_facet |
Menezes, Gisele Barreto Lopes Pereira, Fernanda Albuquerque Duarte, César Augusto Barros Carmo, Theomira Mauadie de Azevedo Silva Filho, Hermes Pedreira da Zarife, Maria Alice Sant’Anna Krieger, Marco Aurélio Reis, Eliana Almeida Gomes Reis, Mitermayer Galvão dos |
| author_role |
author |
| author2 |
Pereira, Fernanda Albuquerque Duarte, César Augusto Barros Carmo, Theomira Mauadie de Azevedo Silva Filho, Hermes Pedreira da Zarife, Maria Alice Sant’Anna Krieger, Marco Aurélio Reis, Eliana Almeida Gomes Reis, Mitermayer Galvão dos |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Menezes, Gisele Barreto Lopes Pereira, Fernanda Albuquerque Duarte, César Augusto Barros Carmo, Theomira Mauadie de Azevedo Silva Filho, Hermes Pedreira da Zarife, Maria Alice Sant’Anna Krieger, Marco Aurélio Reis, Eliana Almeida Gomes Reis, Mitermayer Galvão dos |
| dc.subject.en.pt_BR.fl_str_mv |
HCV HCV transmission Serum HCV load Salivary HCV load |
| topic |
HCV HCV transmission Serum HCV load Salivary HCV load Hepacivirus/isolamento & purificação Hepatite C Crônica/virologia Saliva/virologia Soro/virologia Adulto Estudos de Casos e Controles Estudos Transversais Feminino Genótipo Hepatite C Crônica/sangue Humanos Masculino Meia-Idade RNA Viral/análise Reação em Cadeia da Polimerase em Tempo Real Carga Viral Adulto Jovem |
| dc.subject.decs.pt_BR.fl_str_mv |
Hepacivirus/isolamento & purificação Hepatite C Crônica/virologia Saliva/virologia Soro/virologia Adulto Estudos de Casos e Controles Estudos Transversais Feminino Genótipo Hepatite C Crônica/sangue Humanos Masculino Meia-Idade RNA Viral/análise Reação em Cadeia da Polimerase em Tempo Real Carga Viral Adulto Jovem |
| description |
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biologia Molecular. Salvador, BA, Brasil. |
| publishDate |
2012 |
| dc.date.issued.fl_str_mv |
2012 |
| dc.date.accessioned.fl_str_mv |
2014-04-03T18:30:47Z |
| dc.date.available.fl_str_mv |
2014-04-03T18:30:47Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
MENEZES, Gisele Barreto Lopes et al. Hepatitis C virus quantification in serum and saliva of HCV-infected patients. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 107, n. 5, p. 680-683, 2012. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/7492 |
| dc.identifier.issn.none.fl_str_mv |
1678-8060 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/S0074-02762012000500016 |
| identifier_str_mv |
MENEZES, Gisele Barreto Lopes et al. Hepatitis C virus quantification in serum and saliva of HCV-infected patients. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 107, n. 5, p. 680-683, 2012. 1678-8060 10.1590/S0074-02762012000500016 |
| url |
https://www.arca.fiocruz.br/handle/icict/7492 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Fiocruz |
| publisher.none.fl_str_mv |
Fiocruz |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/7492/1/Gisele%20BLM%20Hepatitis%20C%20virus....pdf https://www.arca.fiocruz.br/bitstream/icict/7492/2/license.txt https://www.arca.fiocruz.br/bitstream/icict/7492/5/Gisele%20BLM%20Hepatitis%20C%20virus....pdf.txt https://www.arca.fiocruz.br/bitstream/icict/7492/4/Gisele%20BLM%20Hepatitis%20C%20virus....pdf.jpg |
| bitstream.checksum.fl_str_mv |
573458d786627c154593ecd239b68a76 7d48279ffeed55da8dfe2f8e81f3b81f 4f7086ae60ff7520e1208cad3dc458a5 eceb0c74334631db7627e86844311d67 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1798325061927567360 |