Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Memórias do Instituto Oswaldo Cruz |
| Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300392 |
Resumo: | The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS. |
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Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazilinfluenza A(H1N1)pmd09resistanceoseltamivir The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS.Instituto Oswaldo Cruz, Ministério da Saúde2013-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300392Memórias do Instituto Oswaldo Cruz v.108 n.3 2013reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762013000300021info:eu-repo/semantics/openAccessMarx,CamilaGregianini,Tatiana SchafferLehmann,Fernanda Kieling MoreiraLunge,Vagner RicardoCarli,Silvia deDambros,Bibiana PaulaTumioto,Gabriela LuchiariSeadi,ClaudeteFonseca,Andre Salvador KazantziIkuta,Niloeng2020-04-25T17:51:24Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:18:59.863Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
| dc.title.none.fl_str_mv |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| title |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| spellingShingle |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil Marx,Camila influenza A(H1N1)pmd09 resistance oseltamivir |
| title_short |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| title_full |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| title_fullStr |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| title_full_unstemmed |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| title_sort |
Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil |
| author |
Marx,Camila |
| author_facet |
Marx,Camila Gregianini,Tatiana Schaffer Lehmann,Fernanda Kieling Moreira Lunge,Vagner Ricardo Carli,Silvia de Dambros,Bibiana Paula Tumioto,Gabriela Luchiari Seadi,Claudete Fonseca,Andre Salvador Kazantzi Ikuta,Nilo |
| author_role |
author |
| author2 |
Gregianini,Tatiana Schaffer Lehmann,Fernanda Kieling Moreira Lunge,Vagner Ricardo Carli,Silvia de Dambros,Bibiana Paula Tumioto,Gabriela Luchiari Seadi,Claudete Fonseca,Andre Salvador Kazantzi Ikuta,Nilo |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Marx,Camila Gregianini,Tatiana Schaffer Lehmann,Fernanda Kieling Moreira Lunge,Vagner Ricardo Carli,Silvia de Dambros,Bibiana Paula Tumioto,Gabriela Luchiari Seadi,Claudete Fonseca,Andre Salvador Kazantzi Ikuta,Nilo |
| dc.subject.por.fl_str_mv |
influenza A(H1N1)pmd09 resistance oseltamivir |
| topic |
influenza A(H1N1)pmd09 resistance oseltamivir |
| dc.description.none.fl_txt_mv |
The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS. |
| description |
The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS. |
| publishDate |
2013 |
| dc.date.none.fl_str_mv |
2013-05-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300392 |
| url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300392 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/S0074-02762013000300021 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
text/html |
| dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.108 n.3 2013 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz |
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Memórias do Instituto Oswaldo Cruz |
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Fundação Oswaldo Cruz |
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FIOCRUZ |
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FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
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