Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 1983 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Memórias do Instituto Oswaldo Cruz |
| Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300001 |
Resumo: | Mice infected with Trypanosoma cruzi were challenged with 2x10[raised to the power of 6] cells of sarcoma 180 (ascite tumor) by i.p. route, on day seven post infection. Tumor development was followed by evaluation of weight gain, by measurement of ascitic fluid produced and enumeration of tumor cells in ascitic fluid. Infected mice were more resitant to tumor development as demonstrated by reduction in ascites formation and by reduction in the number of tumor cells in ascitic fluid, at different time intervals after tumor challenge. The number of peritoneal cells exsudated after tumor inoculation was greater in infected mice than in controls. This increased resitance of mice infected with T. cruzi to tumor development could be due to the action of macrophages activated by the infection and by the action of endotoxins absorbed from the gut or produced by the own parasite. |
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Memórias do Instituto Oswaldo Cruz |
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Evolution of sarcoma 180 in mice infected with Trypanosoma cruziMice infected with Trypanosoma cruzi were challenged with 2x10[raised to the power of 6] cells of sarcoma 180 (ascite tumor) by i.p. route, on day seven post infection. Tumor development was followed by evaluation of weight gain, by measurement of ascitic fluid produced and enumeration of tumor cells in ascitic fluid. Infected mice were more resitant to tumor development as demonstrated by reduction in ascites formation and by reduction in the number of tumor cells in ascitic fluid, at different time intervals after tumor challenge. The number of peritoneal cells exsudated after tumor inoculation was greater in infected mice than in controls. This increased resitance of mice infected with T. cruzi to tumor development could be due to the action of macrophages activated by the infection and by the action of endotoxins absorbed from the gut or produced by the own parasite.Instituto Oswaldo Cruz, Ministério da Saúde1983-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300001Memórias do Instituto Oswaldo Cruz v.78 n.3 1983reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761983000300001info:eu-repo/semantics/openAccessPereira,Fausto Edmundo LimaSassine,William AssadBouhabib,Dimith ChequerLucas,Elton de Almeidaeng2020-04-25T17:45:30Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:00:33.469Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
| dc.title.none.fl_str_mv |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| title |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| spellingShingle |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi Pereira,Fausto Edmundo Lima |
| title_short |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| title_full |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| title_fullStr |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| title_full_unstemmed |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| title_sort |
Evolution of sarcoma 180 in mice infected with Trypanosoma cruzi |
| author |
Pereira,Fausto Edmundo Lima |
| author_facet |
Pereira,Fausto Edmundo Lima Sassine,William Assad Bouhabib,Dimith Chequer Lucas,Elton de Almeida |
| author_role |
author |
| author2 |
Sassine,William Assad Bouhabib,Dimith Chequer Lucas,Elton de Almeida |
| author2_role |
author author author |
| dc.contributor.author.fl_str_mv |
Pereira,Fausto Edmundo Lima Sassine,William Assad Bouhabib,Dimith Chequer Lucas,Elton de Almeida |
| dc.description.none.fl_txt_mv |
Mice infected with Trypanosoma cruzi were challenged with 2x10[raised to the power of 6] cells of sarcoma 180 (ascite tumor) by i.p. route, on day seven post infection. Tumor development was followed by evaluation of weight gain, by measurement of ascitic fluid produced and enumeration of tumor cells in ascitic fluid. Infected mice were more resitant to tumor development as demonstrated by reduction in ascites formation and by reduction in the number of tumor cells in ascitic fluid, at different time intervals after tumor challenge. The number of peritoneal cells exsudated after tumor inoculation was greater in infected mice than in controls. This increased resitance of mice infected with T. cruzi to tumor development could be due to the action of macrophages activated by the infection and by the action of endotoxins absorbed from the gut or produced by the own parasite. |
| description |
Mice infected with Trypanosoma cruzi were challenged with 2x10[raised to the power of 6] cells of sarcoma 180 (ascite tumor) by i.p. route, on day seven post infection. Tumor development was followed by evaluation of weight gain, by measurement of ascitic fluid produced and enumeration of tumor cells in ascitic fluid. Infected mice were more resitant to tumor development as demonstrated by reduction in ascites formation and by reduction in the number of tumor cells in ascitic fluid, at different time intervals after tumor challenge. The number of peritoneal cells exsudated after tumor inoculation was greater in infected mice than in controls. This increased resitance of mice infected with T. cruzi to tumor development could be due to the action of macrophages activated by the infection and by the action of endotoxins absorbed from the gut or produced by the own parasite. |
| publishDate |
1983 |
| dc.date.none.fl_str_mv |
1983-09-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300001 |
| url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761983000300001 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/S0074-02761983000300001 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
text/html |
| dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.78 n.3 1983 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
| reponame_str |
Memórias do Instituto Oswaldo Cruz |
| collection |
Memórias do Instituto Oswaldo Cruz |
| instname_str |
Fundação Oswaldo Cruz |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
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1669937641772023808 |