Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil

Detalhes bibliográficos
Autor(a) principal: Villar,Livia Melo
Data de Publicação: 2002
Outros Autores: Costa,Maria do Carmo Esteves da, Paula,Vanessa Salete de, Gaspar,Ana Maria Coimbra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000300004
Resumo: From June 1 to July 1 1999, an outbreak involving 25 cases of hepatitis A occurred in a public school in Rio de Janeiro, Brazil. Since these cases were notified to the State Health Department, the National Reference Center for Hepatitis Viruses (CNRHV) was required to investigate the extent of hepatitis A virus (HAV) dissemination. Blood samples from all students were tested for IgM and total anti-HAV antibodies using a commercial enzyme-linked immunoassay (ELISA). At the same time, a questionnaire was completed in order to identify possible risk factors for HAV infection. The environmental investigation showed that there was no fecal contamination of the water supply. The epidemiological investigation demonstrated that almost 50% of this population was susceptible to HAV infection and probably person-to-person transmission was the principal mode of virus dissemination. In this situation, a massive vaccination campaign could control the HAV infection.
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spelling Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazilhepatitis A virusoutbreakseroepidemiologypublic schoolRio de JaneiroBrazilFrom June 1 to July 1 1999, an outbreak involving 25 cases of hepatitis A occurred in a public school in Rio de Janeiro, Brazil. Since these cases were notified to the State Health Department, the National Reference Center for Hepatitis Viruses (CNRHV) was required to investigate the extent of hepatitis A virus (HAV) dissemination. Blood samples from all students were tested for IgM and total anti-HAV antibodies using a commercial enzyme-linked immunoassay (ELISA). At the same time, a questionnaire was completed in order to identify possible risk factors for HAV infection. The environmental investigation showed that there was no fecal contamination of the water supply. The epidemiological investigation demonstrated that almost 50% of this population was susceptible to HAV infection and probably person-to-person transmission was the principal mode of virus dissemination. In this situation, a massive vaccination campaign could control the HAV infection.Instituto Oswaldo Cruz, Ministério da Saúde2002-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000300004Memórias do Instituto Oswaldo Cruz v.97 n.3 2002reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762002000300004info:eu-repo/semantics/openAccessVillar,Livia MeloCosta,Maria do Carmo Esteves daPaula,Vanessa Salete deGaspar,Ana Maria Coimbraeng2020-04-25T17:48:44Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:11:00.269Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
title Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
spellingShingle Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
Villar,Livia Melo
hepatitis A virus
outbreak
seroepidemiology
public school
Rio de Janeiro
Brazil
title_short Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
title_full Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
title_fullStr Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
title_full_unstemmed Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
title_sort Hepatitis A Outbreak in a Public School in Rio de Janeiro, Brazil
author Villar,Livia Melo
author_facet Villar,Livia Melo
Costa,Maria do Carmo Esteves da
Paula,Vanessa Salete de
Gaspar,Ana Maria Coimbra
author_role author
author2 Costa,Maria do Carmo Esteves da
Paula,Vanessa Salete de
Gaspar,Ana Maria Coimbra
author2_role author
author
author
dc.contributor.author.fl_str_mv Villar,Livia Melo
Costa,Maria do Carmo Esteves da
Paula,Vanessa Salete de
Gaspar,Ana Maria Coimbra
dc.subject.por.fl_str_mv hepatitis A virus
outbreak
seroepidemiology
public school
Rio de Janeiro
Brazil
topic hepatitis A virus
outbreak
seroepidemiology
public school
Rio de Janeiro
Brazil
dc.description.none.fl_txt_mv From June 1 to July 1 1999, an outbreak involving 25 cases of hepatitis A occurred in a public school in Rio de Janeiro, Brazil. Since these cases were notified to the State Health Department, the National Reference Center for Hepatitis Viruses (CNRHV) was required to investigate the extent of hepatitis A virus (HAV) dissemination. Blood samples from all students were tested for IgM and total anti-HAV antibodies using a commercial enzyme-linked immunoassay (ELISA). At the same time, a questionnaire was completed in order to identify possible risk factors for HAV infection. The environmental investigation showed that there was no fecal contamination of the water supply. The epidemiological investigation demonstrated that almost 50% of this population was susceptible to HAV infection and probably person-to-person transmission was the principal mode of virus dissemination. In this situation, a massive vaccination campaign could control the HAV infection.
description From June 1 to July 1 1999, an outbreak involving 25 cases of hepatitis A occurred in a public school in Rio de Janeiro, Brazil. Since these cases were notified to the State Health Department, the National Reference Center for Hepatitis Viruses (CNRHV) was required to investigate the extent of hepatitis A virus (HAV) dissemination. Blood samples from all students were tested for IgM and total anti-HAV antibodies using a commercial enzyme-linked immunoassay (ELISA). At the same time, a questionnaire was completed in order to identify possible risk factors for HAV infection. The environmental investigation showed that there was no fecal contamination of the water supply. The epidemiological investigation demonstrated that almost 50% of this population was susceptible to HAV infection and probably person-to-person transmission was the principal mode of virus dissemination. In this situation, a massive vaccination campaign could control the HAV infection.
publishDate 2002
dc.date.none.fl_str_mv 2002-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000300004
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762002000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.97 n.3 2002
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
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collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
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