In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe

Detalhes bibliográficos
Autor(a) principal: Barbosa,Theolis
Data de Publicação: 2001
Outros Autores: Arruda,Sérgio, Cavada,Benildo, Grangeiro,Thalles Barbosa, Freitas,Luiz Antônio Rodrigues de, Barral-Netto,Manoel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000500016
Resumo: This paper reports the overall effects of three lectins, extracted from Canavalia brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice popliteal draining lymph nodes. These lectins have presented high stimulatory capacity on lymph node T cells. Additionally, they were able to induce apoptosis and inflammation (frequently associated with high endothelial venule necrosis). The data presented here suggest that the Diocleinae lectins studied can stimulate in vivo T cell activation and apoptosis, as well as present important side effects.
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spelling In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribeadjuvantsapoptosisDiocleinaelectinThis paper reports the overall effects of three lectins, extracted from Canavalia brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice popliteal draining lymph nodes. These lectins have presented high stimulatory capacity on lymph node T cells. Additionally, they were able to induce apoptosis and inflammation (frequently associated with high endothelial venule necrosis). The data presented here suggest that the Diocleinae lectins studied can stimulate in vivo T cell activation and apoptosis, as well as present important side effects.Instituto Oswaldo Cruz, Ministério da Saúde2001-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000500016Memórias do Instituto Oswaldo Cruz v.96 n.5 2001reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762001000500016info:eu-repo/semantics/openAccessBarbosa,TheolisArruda,SérgioCavada,BenildoGrangeiro,Thalles BarbosaFreitas,Luiz Antônio Rodrigues deBarral-Netto,Manoeleng2020-04-25T17:48:34Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:10:25.203Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
spellingShingle In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
Barbosa,Theolis
adjuvants
apoptosis
Diocleinae
lectin
title_short In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_full In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_fullStr In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_full_unstemmed In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_sort In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
author Barbosa,Theolis
author_facet Barbosa,Theolis
Arruda,Sérgio
Cavada,Benildo
Grangeiro,Thalles Barbosa
Freitas,Luiz Antônio Rodrigues de
Barral-Netto,Manoel
author_role author
author2 Arruda,Sérgio
Cavada,Benildo
Grangeiro,Thalles Barbosa
Freitas,Luiz Antônio Rodrigues de
Barral-Netto,Manoel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Barbosa,Theolis
Arruda,Sérgio
Cavada,Benildo
Grangeiro,Thalles Barbosa
Freitas,Luiz Antônio Rodrigues de
Barral-Netto,Manoel
dc.subject.por.fl_str_mv adjuvants
apoptosis
Diocleinae
lectin
topic adjuvants
apoptosis
Diocleinae
lectin
dc.description.none.fl_txt_mv This paper reports the overall effects of three lectins, extracted from Canavalia brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice popliteal draining lymph nodes. These lectins have presented high stimulatory capacity on lymph node T cells. Additionally, they were able to induce apoptosis and inflammation (frequently associated with high endothelial venule necrosis). The data presented here suggest that the Diocleinae lectins studied can stimulate in vivo T cell activation and apoptosis, as well as present important side effects.
description This paper reports the overall effects of three lectins, extracted from Canavalia brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice popliteal draining lymph nodes. These lectins have presented high stimulatory capacity on lymph node T cells. Additionally, they were able to induce apoptosis and inflammation (frequently associated with high endothelial venule necrosis). The data presented here suggest that the Diocleinae lectins studied can stimulate in vivo T cell activation and apoptosis, as well as present important side effects.
publishDate 2001
dc.date.none.fl_str_mv 2001-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000500016
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000500016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762001000500016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.96 n.5 2001
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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