Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Memórias do Instituto Oswaldo Cruz |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000200025 |
Resumo: | This research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia |
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Memórias do Instituto Oswaldo Cruz |
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Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in DogsTrypanosoma evansidogsbiometryElisainmunofluorescent antibody testclinical featuresThis research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemiaInstituto Oswaldo Cruz, Ministério da Saúde1999-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000200025Memórias do Instituto Oswaldo Cruz v.94 n.2 1999reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761999000200025info:eu-repo/semantics/openAccessAquino,Lúcia Padilha Cury Thomaz deMachado,Rosangela ZacariasAlessi,Antônio CarlosMarques,Luiz CarlosCastro,Márcio Botelho deMalheiros,Euclides Bragaeng2020-04-25T17:48:08Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:08:52.752Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
dc.title.none.fl_str_mv |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
title |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
spellingShingle |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs Aquino,Lúcia Padilha Cury Thomaz de Trypanosoma evansi dogs biometry Elisa inmunofluorescent antibody test clinical features |
title_short |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
title_full |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
title_fullStr |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
title_full_unstemmed |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
title_sort |
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs |
author |
Aquino,Lúcia Padilha Cury Thomaz de |
author_facet |
Aquino,Lúcia Padilha Cury Thomaz de Machado,Rosangela Zacarias Alessi,Antônio Carlos Marques,Luiz Carlos Castro,Márcio Botelho de Malheiros,Euclides Braga |
author_role |
author |
author2 |
Machado,Rosangela Zacarias Alessi,Antônio Carlos Marques,Luiz Carlos Castro,Márcio Botelho de Malheiros,Euclides Braga |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Aquino,Lúcia Padilha Cury Thomaz de Machado,Rosangela Zacarias Alessi,Antônio Carlos Marques,Luiz Carlos Castro,Márcio Botelho de Malheiros,Euclides Braga |
dc.subject.por.fl_str_mv |
Trypanosoma evansi dogs biometry Elisa inmunofluorescent antibody test clinical features |
topic |
Trypanosoma evansi dogs biometry Elisa inmunofluorescent antibody test clinical features |
dc.description.none.fl_txt_mv |
This research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia |
description |
This research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia |
publishDate |
1999 |
dc.date.none.fl_str_mv |
1999-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000200025 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000200025 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0074-02761999000200025 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.94 n.2 1999 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
reponame_str |
Memórias do Instituto Oswaldo Cruz |
collection |
Memórias do Instituto Oswaldo Cruz |
instname_str |
Fundação Oswaldo Cruz |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
repository.name.fl_str_mv |
Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
repository.mail.fl_str_mv |
|
_version_ |
1669937675361058816 |