First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil

Detalhes bibliográficos
Autor(a) principal: Fagundes,Aline
Data de Publicação: 2007
Outros Autores: Marzochi,Mauro CA, Fernandes,Octavio, Perez,Mauricio A, Schubach,Armando O, Schubach,Tânia MP, Amendoeira,Maria RR, Mouta-Confort,Eliame, Marzochi,Keyla BF
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000800018
Resumo: The objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease.Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area.
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spelling First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, BrazilLeishmaniaPCRMontenegro skin testsubclinical infectionRio Grande do SulBrazilThe objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease.Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area.Instituto Oswaldo Cruz, Ministério da Saúde2007-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000800018Memórias do Instituto Oswaldo Cruz v.102 n.8 2007reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762007000800018info:eu-repo/semantics/openAccessFagundes,AlineMarzochi,Mauro CAFernandes,OctavioPerez,Mauricio ASchubach,Armando OSchubach,Tânia MPAmendoeira,Maria RRMouta-Confort,EliameMarzochi,Keyla BFeng2020-04-25T17:50:05Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:14:57.814Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
title First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
spellingShingle First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
Fagundes,Aline
Leishmania
PCR
Montenegro skin test
subclinical infection
Rio Grande do Sul
Brazil
title_short First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
title_full First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
title_fullStr First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
title_full_unstemmed First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
title_sort First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
author Fagundes,Aline
author_facet Fagundes,Aline
Marzochi,Mauro CA
Fernandes,Octavio
Perez,Mauricio A
Schubach,Armando O
Schubach,Tânia MP
Amendoeira,Maria RR
Mouta-Confort,Eliame
Marzochi,Keyla BF
author_role author
author2 Marzochi,Mauro CA
Fernandes,Octavio
Perez,Mauricio A
Schubach,Armando O
Schubach,Tânia MP
Amendoeira,Maria RR
Mouta-Confort,Eliame
Marzochi,Keyla BF
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fagundes,Aline
Marzochi,Mauro CA
Fernandes,Octavio
Perez,Mauricio A
Schubach,Armando O
Schubach,Tânia MP
Amendoeira,Maria RR
Mouta-Confort,Eliame
Marzochi,Keyla BF
dc.subject.por.fl_str_mv Leishmania
PCR
Montenegro skin test
subclinical infection
Rio Grande do Sul
Brazil
topic Leishmania
PCR
Montenegro skin test
subclinical infection
Rio Grande do Sul
Brazil
dc.description.none.fl_txt_mv The objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease.Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area.
description The objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease.Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area.
publishDate 2007
dc.date.none.fl_str_mv 2007-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000800018
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000800018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762007000800018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.102 n.8 2007
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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