Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil

Detalhes bibliográficos
Autor(a) principal: Cruz,Márcio R
Data de Publicação: 2004
Outros Autores: Cerqueira,Daniela M, Cruz,Waldenor B, Camara,Geni NL, Brígido,Marcelo M, Silva,Evandro O, Carvalho,Luciano GS, Martins,Cláudia RF
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007
Resumo: We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
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spelling Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazilhuman papillomavirus type 16variantsFederal DistrictBrazilWe report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.Instituto Oswaldo Cruz, Ministério da Saúde2004-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007Memórias do Instituto Oswaldo Cruz v.99 n.3 2004reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762004000300007info:eu-repo/semantics/openAccessCruz,Márcio RCerqueira,Daniela MCruz,Waldenor BCamara,Geni NLBrígido,Marcelo MSilva,Evandro OCarvalho,Luciano GSMartins,Cláudia RFeng2020-04-25T17:49:15Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:12:34.807Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
spellingShingle Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
Cruz,Márcio R
human papillomavirus type 16
variants
Federal District
Brazil
title_short Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_full Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_fullStr Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_full_unstemmed Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_sort Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
author Cruz,Márcio R
author_facet Cruz,Márcio R
Cerqueira,Daniela M
Cruz,Waldenor B
Camara,Geni NL
Brígido,Marcelo M
Silva,Evandro O
Carvalho,Luciano GS
Martins,Cláudia RF
author_role author
author2 Cerqueira,Daniela M
Cruz,Waldenor B
Camara,Geni NL
Brígido,Marcelo M
Silva,Evandro O
Carvalho,Luciano GS
Martins,Cláudia RF
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cruz,Márcio R
Cerqueira,Daniela M
Cruz,Waldenor B
Camara,Geni NL
Brígido,Marcelo M
Silva,Evandro O
Carvalho,Luciano GS
Martins,Cláudia RF
dc.subject.por.fl_str_mv human papillomavirus type 16
variants
Federal District
Brazil
topic human papillomavirus type 16
variants
Federal District
Brazil
dc.description.none.fl_txt_mv We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
description We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
publishDate 2004
dc.date.none.fl_str_mv 2004-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762004000300007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.99 n.3 2004
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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