Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil

Detalhes bibliográficos
Autor(a) principal: Cruz, Márcio R
Data de Publicação: 2004
Outros Autores: Cerqueira, Daniela M, Cruz, Waldenor B, Camara, Geni NL, Brígido, Marcelo de Macedo, Silva, Evandro O, Carvalho, Luciano GS, Martins, Cláudia RF
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/26144
https://dx.doi.org/10.1590/S0074-02762004000300007
Resumo: We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
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spelling Prevalence of human papillomavirus type 16 variants in the Federal District, Central BrazilPapilomavírus humanovariantsWe report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.Em processamentoInstituto Oswaldo Cruz, Ministério da Saúde2017-12-07T04:39:11Z2017-12-07T04:39:11Z2004info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMem. Inst. Oswaldo Cruz,v.99,n.3,p.281-282,2004http://repositorio.unb.br/handle/10482/26144https://dx.doi.org/10.1590/S0074-02762004000300007Cruz, Márcio RCerqueira, Daniela MCruz, Waldenor BCamara, Geni NLBrígido, Marcelo de MacedoSilva, Evandro OCarvalho, Luciano GSMartins, Cláudia RFinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2024-08-28T16:31:55Zoai:repositorio.unb.br:10482/26144Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-08-28T16:31:55Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
spellingShingle Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
Cruz, Márcio R
Papilomavírus humano
variants
title_short Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_full Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_fullStr Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_full_unstemmed Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_sort Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
author Cruz, Márcio R
author_facet Cruz, Márcio R
Cerqueira, Daniela M
Cruz, Waldenor B
Camara, Geni NL
Brígido, Marcelo de Macedo
Silva, Evandro O
Carvalho, Luciano GS
Martins, Cláudia RF
author_role author
author2 Cerqueira, Daniela M
Cruz, Waldenor B
Camara, Geni NL
Brígido, Marcelo de Macedo
Silva, Evandro O
Carvalho, Luciano GS
Martins, Cláudia RF
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cruz, Márcio R
Cerqueira, Daniela M
Cruz, Waldenor B
Camara, Geni NL
Brígido, Marcelo de Macedo
Silva, Evandro O
Carvalho, Luciano GS
Martins, Cláudia RF
dc.subject.por.fl_str_mv Papilomavírus humano
variants
topic Papilomavírus humano
variants
description We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
publishDate 2004
dc.date.none.fl_str_mv 2004
2017-12-07T04:39:11Z
2017-12-07T04:39:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Mem. Inst. Oswaldo Cruz,v.99,n.3,p.281-282,2004
http://repositorio.unb.br/handle/10482/26144
https://dx.doi.org/10.1590/S0074-02762004000300007
identifier_str_mv Mem. Inst. Oswaldo Cruz,v.99,n.3,p.281-282,2004
url http://repositorio.unb.br/handle/10482/26144
https://dx.doi.org/10.1590/S0074-02762004000300007
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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