Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505 |
Resumo: | Abstract The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study’s most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated. |
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Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDSTubeculosisHIVIsoniazidAbstract The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study’s most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2015-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505Cadernos de Saúde Pública v.31 n.12 2015reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311X00154614info:eu-repo/semantics/openAccessAquino,Daniela Silva deMoura,Líbia Cristina Rocha VilelaMaruza,MagdaSilva,Adriana Paula daXimenes,Ricardo Arraes de AlencarLacerda,Heloísa RamosMiranda Filho,Demócrito de BarrosAlbuquerque,Maria de Fátima Pessoa Militão deeng2016-01-29T00:00:00Zoai:scielo:S0102-311X2015001202505Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2016-01-29T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
title |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
spellingShingle |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS Aquino,Daniela Silva de Tubeculosis HIV Isoniazid |
title_short |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
title_full |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
title_fullStr |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
title_full_unstemmed |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
title_sort |
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS |
author |
Aquino,Daniela Silva de |
author_facet |
Aquino,Daniela Silva de Moura,Líbia Cristina Rocha Vilela Maruza,Magda Silva,Adriana Paula da Ximenes,Ricardo Arraes de Alencar Lacerda,Heloísa Ramos Miranda Filho,Demócrito de Barros Albuquerque,Maria de Fátima Pessoa Militão de |
author_role |
author |
author2 |
Moura,Líbia Cristina Rocha Vilela Maruza,Magda Silva,Adriana Paula da Ximenes,Ricardo Arraes de Alencar Lacerda,Heloísa Ramos Miranda Filho,Demócrito de Barros Albuquerque,Maria de Fátima Pessoa Militão de |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Aquino,Daniela Silva de Moura,Líbia Cristina Rocha Vilela Maruza,Magda Silva,Adriana Paula da Ximenes,Ricardo Arraes de Alencar Lacerda,Heloísa Ramos Miranda Filho,Demócrito de Barros Albuquerque,Maria de Fátima Pessoa Militão de |
dc.subject.por.fl_str_mv |
Tubeculosis HIV Isoniazid |
topic |
Tubeculosis HIV Isoniazid |
description |
Abstract The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study’s most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0102-311X00154614 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.31 n.12 2015 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115736216797184 |