Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS

Detalhes bibliográficos
Autor(a) principal: Aquino,Daniela Silva de
Data de Publicação: 2015
Outros Autores: Moura,Líbia Cristina Rocha Vilela, Maruza,Magda, Silva,Adriana Paula da, Ximenes,Ricardo Arraes de Alencar, Lacerda,Heloísa Ramos, Miranda Filho,Demócrito de Barros, Albuquerque,Maria de Fátima Pessoa Militão de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505
Resumo: Abstract The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study’s most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated.
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spelling Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDSTubeculosisHIVIsoniazidAbstract The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study’s most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2015-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505Cadernos de Saúde Pública v.31 n.12 2015reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311X00154614info:eu-repo/semantics/openAccessAquino,Daniela Silva deMoura,Líbia Cristina Rocha VilelaMaruza,MagdaSilva,Adriana Paula daXimenes,Ricardo Arraes de AlencarLacerda,Heloísa RamosMiranda Filho,Demócrito de BarrosAlbuquerque,Maria de Fátima Pessoa Militão deeng2016-01-29T00:00:00Zoai:scielo:S0102-311X2015001202505Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2016-01-29T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
title Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
spellingShingle Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
Aquino,Daniela Silva de
Tubeculosis
HIV
Isoniazid
title_short Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
title_full Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
title_fullStr Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
title_full_unstemmed Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
title_sort Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
author Aquino,Daniela Silva de
author_facet Aquino,Daniela Silva de
Moura,Líbia Cristina Rocha Vilela
Maruza,Magda
Silva,Adriana Paula da
Ximenes,Ricardo Arraes de Alencar
Lacerda,Heloísa Ramos
Miranda Filho,Demócrito de Barros
Albuquerque,Maria de Fátima Pessoa Militão de
author_role author
author2 Moura,Líbia Cristina Rocha Vilela
Maruza,Magda
Silva,Adriana Paula da
Ximenes,Ricardo Arraes de Alencar
Lacerda,Heloísa Ramos
Miranda Filho,Demócrito de Barros
Albuquerque,Maria de Fátima Pessoa Militão de
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Aquino,Daniela Silva de
Moura,Líbia Cristina Rocha Vilela
Maruza,Magda
Silva,Adriana Paula da
Ximenes,Ricardo Arraes de Alencar
Lacerda,Heloísa Ramos
Miranda Filho,Demócrito de Barros
Albuquerque,Maria de Fátima Pessoa Militão de
dc.subject.por.fl_str_mv Tubeculosis
HIV
Isoniazid
topic Tubeculosis
HIV
Isoniazid
description Abstract The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study’s most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2015001202505
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0102-311X00154614
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
dc.source.none.fl_str_mv Cadernos de Saúde Pública v.31 n.12 2015
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
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