Chemical exposure during pregnancy and oral clefts in newborns

Detalhes bibliográficos
Autor(a) principal: Leite,Isabel Cristina Gonçalves
Data de Publicação: 2002
Outros Autores: Paumgartten,Francisco José Roma, Koifman,Sérgio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2002000100003
Resumo: This article presents a literature review on the risk factors for oral clefts (lip and/or palate), emphasizing discussion of maternal exposure to endocrine disruptors. Several studies have identified the risk of cigarette smoking and alcohol consumption, use of anticonvulsivant drugs, and exposure to organic solvents. A protective effect has been shown for supplementation with folic acid. As with other chemicals, the risk associated with exposure to sex hormones is still obscure, although some authors describe a moderate risk level. New studies addressing this hypothesis need to be conducted, while the population exposed to these endocrine disrupters is increasing.
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spelling Chemical exposure during pregnancy and oral clefts in newbornsCleft PalateCleft LipHormonesRisk FactorsThis article presents a literature review on the risk factors for oral clefts (lip and/or palate), emphasizing discussion of maternal exposure to endocrine disruptors. Several studies have identified the risk of cigarette smoking and alcohol consumption, use of anticonvulsivant drugs, and exposure to organic solvents. A protective effect has been shown for supplementation with folic acid. As with other chemicals, the risk associated with exposure to sex hormones is still obscure, although some authors describe a moderate risk level. New studies addressing this hypothesis need to be conducted, while the population exposed to these endocrine disrupters is increasing.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2002-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2002000100003Cadernos de Saúde Pública v.18 n.1 2002reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/S0102-311X2002000100003info:eu-repo/semantics/openAccessLeite,Isabel Cristina GonçalvesPaumgartten,Francisco José RomaKoifman,Sérgioeng2002-03-18T00:00:00Zoai:scielo:S0102-311X2002000100003Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2002-03-18T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Chemical exposure during pregnancy and oral clefts in newborns
title Chemical exposure during pregnancy and oral clefts in newborns
spellingShingle Chemical exposure during pregnancy and oral clefts in newborns
Leite,Isabel Cristina Gonçalves
Cleft Palate
Cleft Lip
Hormones
Risk Factors
title_short Chemical exposure during pregnancy and oral clefts in newborns
title_full Chemical exposure during pregnancy and oral clefts in newborns
title_fullStr Chemical exposure during pregnancy and oral clefts in newborns
title_full_unstemmed Chemical exposure during pregnancy and oral clefts in newborns
title_sort Chemical exposure during pregnancy and oral clefts in newborns
author Leite,Isabel Cristina Gonçalves
author_facet Leite,Isabel Cristina Gonçalves
Paumgartten,Francisco José Roma
Koifman,Sérgio
author_role author
author2 Paumgartten,Francisco José Roma
Koifman,Sérgio
author2_role author
author
dc.contributor.author.fl_str_mv Leite,Isabel Cristina Gonçalves
Paumgartten,Francisco José Roma
Koifman,Sérgio
dc.subject.por.fl_str_mv Cleft Palate
Cleft Lip
Hormones
Risk Factors
topic Cleft Palate
Cleft Lip
Hormones
Risk Factors
description This article presents a literature review on the risk factors for oral clefts (lip and/or palate), emphasizing discussion of maternal exposure to endocrine disruptors. Several studies have identified the risk of cigarette smoking and alcohol consumption, use of anticonvulsivant drugs, and exposure to organic solvents. A protective effect has been shown for supplementation with folic acid. As with other chemicals, the risk associated with exposure to sex hormones is still obscure, although some authors describe a moderate risk level. New studies addressing this hypothesis need to be conducted, while the population exposed to these endocrine disrupters is increasing.
publishDate 2002
dc.date.none.fl_str_mv 2002-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2002000100003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2002000100003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-311X2002000100003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
dc.source.none.fl_str_mv Cadernos de Saúde Pública v.18 n.1 2002
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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reponame_str Cadernos de Saúde Pública
collection Cadernos de Saúde Pública
repository.name.fl_str_mv Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br
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