Residential radon and lung cancer: a cohort study in Galicia, Spain
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007 |
Resumo: | Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher. |
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Residential radon and lung cancer: a cohort study in Galicia, SpainRadonEnvironmental CarcinogensRadiation ExposureLung NeoplasmsCase-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007Cadernos de Saúde Pública v.33 n.6 2017reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311x00189415info:eu-repo/semantics/openAccessBarbosa-Lorenzo,RaquelRuano-Ravina,AlbertoCerdeira-Caramés,SaraRaíces-Aldrey,MónicaBarros-Dios,Juan M.eng2017-06-29T00:00:00Zoai:scielo:S0102-311X2017000605007Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2017-06-29T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
title |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
spellingShingle |
Residential radon and lung cancer: a cohort study in Galicia, Spain Barbosa-Lorenzo,Raquel Radon Environmental Carcinogens Radiation Exposure Lung Neoplasms |
title_short |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
title_full |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
title_fullStr |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
title_full_unstemmed |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
title_sort |
Residential radon and lung cancer: a cohort study in Galicia, Spain |
author |
Barbosa-Lorenzo,Raquel |
author_facet |
Barbosa-Lorenzo,Raquel Ruano-Ravina,Alberto Cerdeira-Caramés,Sara Raíces-Aldrey,Mónica Barros-Dios,Juan M. |
author_role |
author |
author2 |
Ruano-Ravina,Alberto Cerdeira-Caramés,Sara Raíces-Aldrey,Mónica Barros-Dios,Juan M. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barbosa-Lorenzo,Raquel Ruano-Ravina,Alberto Cerdeira-Caramés,Sara Raíces-Aldrey,Mónica Barros-Dios,Juan M. |
dc.subject.por.fl_str_mv |
Radon Environmental Carcinogens Radiation Exposure Lung Neoplasms |
topic |
Radon Environmental Carcinogens Radiation Exposure Lung Neoplasms |
description |
Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0102-311x00189415 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.33 n.6 2017 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115737586237440 |