Residential radon and lung cancer: a cohort study in Galicia, Spain

Detalhes bibliográficos
Autor(a) principal: Barbosa-Lorenzo,Raquel
Data de Publicação: 2017
Outros Autores: Ruano-Ravina,Alberto, Cerdeira-Caramés,Sara, Raíces-Aldrey,Mónica, Barros-Dios,Juan M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cadernos de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007
Resumo: Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher.
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spelling Residential radon and lung cancer: a cohort study in Galicia, SpainRadonEnvironmental CarcinogensRadiation ExposureLung NeoplasmsCase-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007Cadernos de Saúde Pública v.33 n.6 2017reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311x00189415info:eu-repo/semantics/openAccessBarbosa-Lorenzo,RaquelRuano-Ravina,AlbertoCerdeira-Caramés,SaraRaíces-Aldrey,MónicaBarros-Dios,Juan M.eng2017-06-29T00:00:00Zoai:scielo:S0102-311X2017000605007Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2017-06-29T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Residential radon and lung cancer: a cohort study in Galicia, Spain
title Residential radon and lung cancer: a cohort study in Galicia, Spain
spellingShingle Residential radon and lung cancer: a cohort study in Galicia, Spain
Barbosa-Lorenzo,Raquel
Radon
Environmental Carcinogens
Radiation Exposure
Lung Neoplasms
title_short Residential radon and lung cancer: a cohort study in Galicia, Spain
title_full Residential radon and lung cancer: a cohort study in Galicia, Spain
title_fullStr Residential radon and lung cancer: a cohort study in Galicia, Spain
title_full_unstemmed Residential radon and lung cancer: a cohort study in Galicia, Spain
title_sort Residential radon and lung cancer: a cohort study in Galicia, Spain
author Barbosa-Lorenzo,Raquel
author_facet Barbosa-Lorenzo,Raquel
Ruano-Ravina,Alberto
Cerdeira-Caramés,Sara
Raíces-Aldrey,Mónica
Barros-Dios,Juan M.
author_role author
author2 Ruano-Ravina,Alberto
Cerdeira-Caramés,Sara
Raíces-Aldrey,Mónica
Barros-Dios,Juan M.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Barbosa-Lorenzo,Raquel
Ruano-Ravina,Alberto
Cerdeira-Caramés,Sara
Raíces-Aldrey,Mónica
Barros-Dios,Juan M.
dc.subject.por.fl_str_mv Radon
Environmental Carcinogens
Radiation Exposure
Lung Neoplasms
topic Radon
Environmental Carcinogens
Radiation Exposure
Lung Neoplasms
description Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0102-311x00189415
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dc.publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
publisher.none.fl_str_mv Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
dc.source.none.fl_str_mv Cadernos de Saúde Pública v.33 n.6 2017
reponame:Cadernos de Saúde Pública
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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collection Cadernos de Saúde Pública
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