Reajustando o limite de tolerância biológica aplicado à plumbemia no Brasil

• Autor(a) principal: Cordeiro, Ricardo
• Data de Publicação: 1996
• Outros Autores: Lima Filho, Euclydes Custódio de, Salgado, Paulo Eduardo deToledo
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Cadernos de Saúde Pública
• Texto Completo: https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/732
• topic: Chumbo; Intoxicação por Chumbo; Doenças Ocupacionais; Saúde do Trabalhador; Exposição Ambiental

We randomly selected twenty lead workers from an electric accumulator factory in the State of São Paulo, Brazil, whose blood lead level and urinary d-aminolevulinic acid level were below 60 mg/dL and 10 mg/L, respectively. The workers were submitted to a standard motor nerve conduction velocity study of the right radial nerves, in addition to blood lead dosage. Based on these measures, a first-order linear regression model was adjusted, where the dependent variable was conduction velocity and the independent variable was the blood lead level. Analyzing the fitted model, we inferred that the negative predictive value of the Brazilian biological exposure limit is 0.63. In order for the above biological exposure limit to have a negative predictive value of 0.99, the study suggests that it be reduced from its present value (60 mg/dL) to 32 mg/dL.