Research of endotoxins in hemodialysis water

Detalhes bibliográficos
Autor(a) principal: Câmara, Sonia Aparecida Viana
Data de Publicação: 2018
Outros Autores: Pivetta, Ariana Novaes da Silva, Uehara, Gabriela Hatsuko Mendes
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Vigilância Sanitária em Debate
Texto Completo: https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158
Resumo: Introduction: Chronic kidney disease is characterized by loss of kidney function leading to a physiological and biological functional imbalance. One of the treatments necessary for the chronic renal patient is hemodialysis. Water quality is critical to reducing patient risk. Resolution RDC n. 11, of March 13th, 2014, from Brazilian Health Regulatory Agency (Anvisa) establishesd the search for endotoxins, as venous contamination by endotoxins may cause various problems in the patients’ health. Objective: To identify endotoxins in purified water for hemodialysis. Method: This is a Quantitative Descriptive Cross-sectional Study to verify the presence of endotoxins in 126 water samples collected at two points (post-reverse osmosis and reuse room) at six renal substitution therapy clinics, by the State Sanitary Surveillance, and analyzed in the LACEN, in Campo Grande, MS, in 2016. Results: Of the 68 water samples collected after the reverse osmosis process, three (4.41%), and of the 58 samples collected in the reuse room, six (10.52%) presented endotoxin results above the amount allowed by the legislation (0.25 EU\mL). Conclusions: Results indicate membrane involvement of the reverse osmosis process, and, or presence of biofilm in the pipes, and inefficiency of the cleaning process of the reservoir, pipes, and machines disinfection process.
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spelling Research of endotoxins in hemodialysis waterPesquisa de endotoxinas em água de hemodiáliseInsuficiência Renal CrônicaEndotoxinasÁgua para DiáliseVigilância em Saúde PúblicaChronic Renal FailureEndotoxinsDialysis WaterPublic Health SurveillanceIntroduction: Chronic kidney disease is characterized by loss of kidney function leading to a physiological and biological functional imbalance. One of the treatments necessary for the chronic renal patient is hemodialysis. Water quality is critical to reducing patient risk. Resolution RDC n. 11, of March 13th, 2014, from Brazilian Health Regulatory Agency (Anvisa) establishesd the search for endotoxins, as venous contamination by endotoxins may cause various problems in the patients’ health. Objective: To identify endotoxins in purified water for hemodialysis. Method: This is a Quantitative Descriptive Cross-sectional Study to verify the presence of endotoxins in 126 water samples collected at two points (post-reverse osmosis and reuse room) at six renal substitution therapy clinics, by the State Sanitary Surveillance, and analyzed in the LACEN, in Campo Grande, MS, in 2016. Results: Of the 68 water samples collected after the reverse osmosis process, three (4.41%), and of the 58 samples collected in the reuse room, six (10.52%) presented endotoxin results above the amount allowed by the legislation (0.25 EU\mL). Conclusions: Results indicate membrane involvement of the reverse osmosis process, and, or presence of biofilm in the pipes, and inefficiency of the cleaning process of the reservoir, pipes, and machines disinfection process.Introdução: A doença renal crônica caracteriza-se pela perda da função dos rins levando a um desequilíbrio funcional, fisiológico e biológico. Um dos tratamentos necessários ao paciente renal crônico é a hemodiálise onde a qualidade da água é de fundamental importância para reduzir riscos aos pacientes. Através da Resolução RDC nº 11, de 13 março de 2014, a Agência Nacional de Vigilância Sanitária (Anvisa) estabeleceu a pesquisa de endotoxinas, cuja contaminação por via venosa poderá causar vários agravos à saúde dos pacientes. Objetivo: Identificar endotoxinas em água purificada para hemodiálise. Método: Trata-se de um estudo transversal descritivo quantitativo para verificação da presença de endotoxinas em 126 amostras de água, coletadas em dois pontos (pós-osmose reversa e sala de reúso) nas seis clínicas de terapia renal substitutiva, pela Vigilância Sanitária Estadual, analisadas no LACEN, em Campo Grande, Mato Grosso do Sul, 2016. Resultados: Das 68 amostras de água coletadas após o processo de osmose reversa, três (4,41%) e das 58 amostras coletadas na sala de reúso, seis (10,34%) apresentaram resultados de endotoxinas acima do valor permitido pela legislação (0,25 EU\mL). Conclusões: Os resultados encontrados indicam comprometimento da membrana do processo de osmose reversa e, ou presença de biofilme nas tubulações, ineficácia do processo de limpeza do reservatório, tubulações, e desinfecção das máquinas.Instituto Nacional de Controle de Qualidade em Saúde2018-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion"Peer-reviewed article""Artículo revisado por pares""Artigo avaliado pelos pares"application/pdfapplication/pdfhttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/115810.22239/2317-269X.01158Health Surveillance under Debate: Society, Science & Technology ; Vol. 6 No. 4 (2018): November; 42-46Vigilancia en Salud en Debate: Sociedad, Ciencia y Tecnología; Vol. 6 Núm. 4 (2018): Noviembre; 42-46Vigil Sanit Debate, Rio de Janeiro; v. 6 n. 4 (2018): Novembro; 42-462317-269Xreponame:Vigilância Sanitária em Debateinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporenghttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/543https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/1063Copyright (c) 2018 Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia (Health Surveillance under Debate: Society, Science & Technology) – Visa em Debatehttps://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessCâmara, Sonia Aparecida VianaPivetta, Ariana Novaes da SilvaUehara, Gabriela Hatsuko Mendes2023-06-27T15:20:10Zoai:ojs.visaemdebate.incqs.fiocruz.br:article/1158Revistahttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebatePUBhttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/oaiincqs.visaemdebate@fiocruz.br || gisele.neves@fiocruz.br2317-269X2317-269Xopendoar:2023-06-27T15:20:10Vigilância Sanitária em Debate - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Research of endotoxins in hemodialysis water
Pesquisa de endotoxinas em água de hemodiálise
title Research of endotoxins in hemodialysis water
spellingShingle Research of endotoxins in hemodialysis water
Câmara, Sonia Aparecida Viana
Insuficiência Renal Crônica
Endotoxinas
Água para Diálise
Vigilância em Saúde Pública
Chronic Renal Failure
Endotoxins
Dialysis Water
Public Health Surveillance
title_short Research of endotoxins in hemodialysis water
title_full Research of endotoxins in hemodialysis water
title_fullStr Research of endotoxins in hemodialysis water
title_full_unstemmed Research of endotoxins in hemodialysis water
title_sort Research of endotoxins in hemodialysis water
author Câmara, Sonia Aparecida Viana
author_facet Câmara, Sonia Aparecida Viana
Pivetta, Ariana Novaes da Silva
Uehara, Gabriela Hatsuko Mendes
author_role author
author2 Pivetta, Ariana Novaes da Silva
Uehara, Gabriela Hatsuko Mendes
author2_role author
author
dc.contributor.author.fl_str_mv Câmara, Sonia Aparecida Viana
Pivetta, Ariana Novaes da Silva
Uehara, Gabriela Hatsuko Mendes
dc.subject.por.fl_str_mv Insuficiência Renal Crônica
Endotoxinas
Água para Diálise
Vigilância em Saúde Pública
Chronic Renal Failure
Endotoxins
Dialysis Water
Public Health Surveillance
topic Insuficiência Renal Crônica
Endotoxinas
Água para Diálise
Vigilância em Saúde Pública
Chronic Renal Failure
Endotoxins
Dialysis Water
Public Health Surveillance
description Introduction: Chronic kidney disease is characterized by loss of kidney function leading to a physiological and biological functional imbalance. One of the treatments necessary for the chronic renal patient is hemodialysis. Water quality is critical to reducing patient risk. Resolution RDC n. 11, of March 13th, 2014, from Brazilian Health Regulatory Agency (Anvisa) establishesd the search for endotoxins, as venous contamination by endotoxins may cause various problems in the patients’ health. Objective: To identify endotoxins in purified water for hemodialysis. Method: This is a Quantitative Descriptive Cross-sectional Study to verify the presence of endotoxins in 126 water samples collected at two points (post-reverse osmosis and reuse room) at six renal substitution therapy clinics, by the State Sanitary Surveillance, and analyzed in the LACEN, in Campo Grande, MS, in 2016. Results: Of the 68 water samples collected after the reverse osmosis process, three (4.41%), and of the 58 samples collected in the reuse room, six (10.52%) presented endotoxin results above the amount allowed by the legislation (0.25 EU\mL). Conclusions: Results indicate membrane involvement of the reverse osmosis process, and, or presence of biofilm in the pipes, and inefficiency of the cleaning process of the reservoir, pipes, and machines disinfection process.
publishDate 2018
dc.date.none.fl_str_mv 2018-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
"Peer-reviewed article"
"Artículo revisado por pares"
"Artigo avaliado pelos pares"
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158
10.22239/2317-269X.01158
url https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158
identifier_str_mv 10.22239/2317-269X.01158
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/543
https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/1063
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Instituto Nacional de Controle de Qualidade em Saúde
publisher.none.fl_str_mv Instituto Nacional de Controle de Qualidade em Saúde
dc.source.none.fl_str_mv Health Surveillance under Debate: Society, Science & Technology ; Vol. 6 No. 4 (2018): November; 42-46
Vigilancia en Salud en Debate: Sociedad, Ciencia y Tecnología; Vol. 6 Núm. 4 (2018): Noviembre; 42-46
Vigil Sanit Debate, Rio de Janeiro; v. 6 n. 4 (2018): Novembro; 42-46
2317-269X
reponame:Vigilância Sanitária em Debate
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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reponame_str Vigilância Sanitária em Debate
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repository.name.fl_str_mv Vigilância Sanitária em Debate - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv incqs.visaemdebate@fiocruz.br || gisele.neves@fiocruz.br
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