Research of endotoxins in hemodialysis water
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Vigilância Sanitária em Debate |
Texto Completo: | https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158 |
Resumo: | Introduction: Chronic kidney disease is characterized by loss of kidney function leading to a physiological and biological functional imbalance. One of the treatments necessary for the chronic renal patient is hemodialysis. Water quality is critical to reducing patient risk. Resolution RDC n. 11, of March 13th, 2014, from Brazilian Health Regulatory Agency (Anvisa) establishesd the search for endotoxins, as venous contamination by endotoxins may cause various problems in the patients’ health. Objective: To identify endotoxins in purified water for hemodialysis. Method: This is a Quantitative Descriptive Cross-sectional Study to verify the presence of endotoxins in 126 water samples collected at two points (post-reverse osmosis and reuse room) at six renal substitution therapy clinics, by the State Sanitary Surveillance, and analyzed in the LACEN, in Campo Grande, MS, in 2016. Results: Of the 68 water samples collected after the reverse osmosis process, three (4.41%), and of the 58 samples collected in the reuse room, six (10.52%) presented endotoxin results above the amount allowed by the legislation (0.25 EU\mL). Conclusions: Results indicate membrane involvement of the reverse osmosis process, and, or presence of biofilm in the pipes, and inefficiency of the cleaning process of the reservoir, pipes, and machines disinfection process. |
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Research of endotoxins in hemodialysis waterPesquisa de endotoxinas em água de hemodiáliseInsuficiência Renal CrônicaEndotoxinasÁgua para DiáliseVigilância em Saúde PúblicaChronic Renal FailureEndotoxinsDialysis WaterPublic Health SurveillanceIntroduction: Chronic kidney disease is characterized by loss of kidney function leading to a physiological and biological functional imbalance. One of the treatments necessary for the chronic renal patient is hemodialysis. Water quality is critical to reducing patient risk. Resolution RDC n. 11, of March 13th, 2014, from Brazilian Health Regulatory Agency (Anvisa) establishesd the search for endotoxins, as venous contamination by endotoxins may cause various problems in the patients’ health. Objective: To identify endotoxins in purified water for hemodialysis. Method: This is a Quantitative Descriptive Cross-sectional Study to verify the presence of endotoxins in 126 water samples collected at two points (post-reverse osmosis and reuse room) at six renal substitution therapy clinics, by the State Sanitary Surveillance, and analyzed in the LACEN, in Campo Grande, MS, in 2016. Results: Of the 68 water samples collected after the reverse osmosis process, three (4.41%), and of the 58 samples collected in the reuse room, six (10.52%) presented endotoxin results above the amount allowed by the legislation (0.25 EU\mL). Conclusions: Results indicate membrane involvement of the reverse osmosis process, and, or presence of biofilm in the pipes, and inefficiency of the cleaning process of the reservoir, pipes, and machines disinfection process.Introdução: A doença renal crônica caracteriza-se pela perda da função dos rins levando a um desequilíbrio funcional, fisiológico e biológico. Um dos tratamentos necessários ao paciente renal crônico é a hemodiálise onde a qualidade da água é de fundamental importância para reduzir riscos aos pacientes. Através da Resolução RDC nº 11, de 13 março de 2014, a Agência Nacional de Vigilância Sanitária (Anvisa) estabeleceu a pesquisa de endotoxinas, cuja contaminação por via venosa poderá causar vários agravos à saúde dos pacientes. Objetivo: Identificar endotoxinas em água purificada para hemodiálise. Método: Trata-se de um estudo transversal descritivo quantitativo para verificação da presença de endotoxinas em 126 amostras de água, coletadas em dois pontos (pós-osmose reversa e sala de reúso) nas seis clínicas de terapia renal substitutiva, pela Vigilância Sanitária Estadual, analisadas no LACEN, em Campo Grande, Mato Grosso do Sul, 2016. Resultados: Das 68 amostras de água coletadas após o processo de osmose reversa, três (4,41%) e das 58 amostras coletadas na sala de reúso, seis (10,34%) apresentaram resultados de endotoxinas acima do valor permitido pela legislação (0,25 EU\mL). Conclusões: Os resultados encontrados indicam comprometimento da membrana do processo de osmose reversa e, ou presença de biofilme nas tubulações, ineficácia do processo de limpeza do reservatório, tubulações, e desinfecção das máquinas.Instituto Nacional de Controle de Qualidade em Saúde2018-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion"Peer-reviewed article""Artículo revisado por pares""Artigo avaliado pelos pares"application/pdfapplication/pdfhttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/115810.22239/2317-269X.01158Health Surveillance under Debate: Society, Science & Technology ; Vol. 6 No. 4 (2018): November; 42-46Vigilancia en Salud en Debate: Sociedad, Ciencia y Tecnología; Vol. 6 Núm. 4 (2018): Noviembre; 42-46Vigil Sanit Debate, Rio de Janeiro; v. 6 n. 4 (2018): Novembro; 42-462317-269Xreponame:Vigilância Sanitária em Debateinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporenghttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/543https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/1063Copyright (c) 2018 Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia (Health Surveillance under Debate: Society, Science & Technology) – Visa em Debatehttps://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessCâmara, Sonia Aparecida VianaPivetta, Ariana Novaes da SilvaUehara, Gabriela Hatsuko Mendes2023-06-27T15:20:10Zoai:ojs.visaemdebate.incqs.fiocruz.br:article/1158Revistahttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebatePUBhttps://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/oaiincqs.visaemdebate@fiocruz.br || gisele.neves@fiocruz.br2317-269X2317-269Xopendoar:2023-06-27T15:20:10Vigilância Sanitária em Debate - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Research of endotoxins in hemodialysis water Pesquisa de endotoxinas em água de hemodiálise |
title |
Research of endotoxins in hemodialysis water |
spellingShingle |
Research of endotoxins in hemodialysis water Câmara, Sonia Aparecida Viana Insuficiência Renal Crônica Endotoxinas Água para Diálise Vigilância em Saúde Pública Chronic Renal Failure Endotoxins Dialysis Water Public Health Surveillance |
title_short |
Research of endotoxins in hemodialysis water |
title_full |
Research of endotoxins in hemodialysis water |
title_fullStr |
Research of endotoxins in hemodialysis water |
title_full_unstemmed |
Research of endotoxins in hemodialysis water |
title_sort |
Research of endotoxins in hemodialysis water |
author |
Câmara, Sonia Aparecida Viana |
author_facet |
Câmara, Sonia Aparecida Viana Pivetta, Ariana Novaes da Silva Uehara, Gabriela Hatsuko Mendes |
author_role |
author |
author2 |
Pivetta, Ariana Novaes da Silva Uehara, Gabriela Hatsuko Mendes |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Câmara, Sonia Aparecida Viana Pivetta, Ariana Novaes da Silva Uehara, Gabriela Hatsuko Mendes |
dc.subject.por.fl_str_mv |
Insuficiência Renal Crônica Endotoxinas Água para Diálise Vigilância em Saúde Pública Chronic Renal Failure Endotoxins Dialysis Water Public Health Surveillance |
topic |
Insuficiência Renal Crônica Endotoxinas Água para Diálise Vigilância em Saúde Pública Chronic Renal Failure Endotoxins Dialysis Water Public Health Surveillance |
description |
Introduction: Chronic kidney disease is characterized by loss of kidney function leading to a physiological and biological functional imbalance. One of the treatments necessary for the chronic renal patient is hemodialysis. Water quality is critical to reducing patient risk. Resolution RDC n. 11, of March 13th, 2014, from Brazilian Health Regulatory Agency (Anvisa) establishesd the search for endotoxins, as venous contamination by endotoxins may cause various problems in the patients’ health. Objective: To identify endotoxins in purified water for hemodialysis. Method: This is a Quantitative Descriptive Cross-sectional Study to verify the presence of endotoxins in 126 water samples collected at two points (post-reverse osmosis and reuse room) at six renal substitution therapy clinics, by the State Sanitary Surveillance, and analyzed in the LACEN, in Campo Grande, MS, in 2016. Results: Of the 68 water samples collected after the reverse osmosis process, three (4.41%), and of the 58 samples collected in the reuse room, six (10.52%) presented endotoxin results above the amount allowed by the legislation (0.25 EU\mL). Conclusions: Results indicate membrane involvement of the reverse osmosis process, and, or presence of biofilm in the pipes, and inefficiency of the cleaning process of the reservoir, pipes, and machines disinfection process. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion "Peer-reviewed article" "Artículo revisado por pares" "Artigo avaliado pelos pares" |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158 10.22239/2317-269X.01158 |
url |
https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158 |
identifier_str_mv |
10.22239/2317-269X.01158 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/543 https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1158/1063 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Nacional de Controle de Qualidade em Saúde |
publisher.none.fl_str_mv |
Instituto Nacional de Controle de Qualidade em Saúde |
dc.source.none.fl_str_mv |
Health Surveillance under Debate: Society, Science & Technology ; Vol. 6 No. 4 (2018): November; 42-46 Vigilancia en Salud en Debate: Sociedad, Ciencia y Tecnología; Vol. 6 Núm. 4 (2018): Noviembre; 42-46 Vigil Sanit Debate, Rio de Janeiro; v. 6 n. 4 (2018): Novembro; 42-46 2317-269X reponame:Vigilância Sanitária em Debate instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Vigilância Sanitária em Debate |
collection |
Vigilância Sanitária em Debate |
repository.name.fl_str_mv |
Vigilância Sanitária em Debate - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
incqs.visaemdebate@fiocruz.br || gisele.neves@fiocruz.br |
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1797042045253058560 |