Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005)
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Científica da Faculdade de Medicina de Campos |
Texto Completo: | https://www.fmc.br/ojs/index.php/RCFMC/article/view/137 |
Resumo: | Introduction: Birth defects constitute simple or multiple alterations of structure, function and/or metabolism that result in physical or mental disabilities, the leading causes of child morbidity and mortality worldwide. Its etiology is diverse and it may or not be genetic. In Brazil, approximately 2 to 3% of all live births are affected by some type of malformation. Nevertheless, variations by gender, ethnicity and place of residence up to 8% have been reported. Objectives: To evaluate the occurrence of birth defects in the Northern Region of the State of Rio de Janeiro, Brazil, which comprises nine municipalities: Campos dos Goytacazes, Macaé, São João da Barra, Conceição de Macabu, São Francisco de Itabapoana, Quissamã, São Fidélis, Carapebus, Cardoso Moreira. Methods: Information was for the year period 1999-2005 from the Live Birth Information Notification System, SINASC. Frequencies were calculated for the variables: municipality, year of notification, category of system affected, maternal age and affected gender. Results: Considering the category of system affected, year of notification and municipality, the cumulative number of notified birth defects was 425. Distributed by affected gender and maternal age, there were 440 notifications, without significant differences (Student t-test p = 0.2181). Prevalence of notified birth defects was 47/10,000 live births (mean annual frequency 0.46% ± 0.11%). The rate of birth defects in males (0.54) was higher than in females (0.46), but not significantly different from the expected values (c2 test pmales =0.7180; pfemales p = 0.5956). The most frequent birth defects involved the central nervous system (21% of all birth defects; 0.097% of all live births) and the musculoskeletal system (20.5% of all birth defects; 0.095% of all live births). The majority (63%) of affected children were born to women aged 20-34 years and the least (9.7%) to mothers aged 35-44 years. The majority of affected children were born in Campos dos Goytacazes (64%) and the least (0.7%) in Cardoso Moreira. Conclusions: The prevalence of birth defects for the Northern Region of the State is approximately half the rates reported by other studies in Brazil, including the city of Rio de Janeiro. Given that the distribution of all live births in the Northern Region of the State is indistinguishable from the National mean birth rates per maternal age distribution, the data point to a significant sub notification for the interior of the State. |
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Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005)Prevalência de malformações congênitas na Região Norte do Estado do Rio de Janeiro: uma avaliação das notificações de nascidos vivos (1999-2005)idade maternamalformação congênitaprevalênciaSINASCbirth defectscongenital defecongenital defectsmaternal ageprevalenceSINASCIntroduction: Birth defects constitute simple or multiple alterations of structure, function and/or metabolism that result in physical or mental disabilities, the leading causes of child morbidity and mortality worldwide. Its etiology is diverse and it may or not be genetic. In Brazil, approximately 2 to 3% of all live births are affected by some type of malformation. Nevertheless, variations by gender, ethnicity and place of residence up to 8% have been reported. Objectives: To evaluate the occurrence of birth defects in the Northern Region of the State of Rio de Janeiro, Brazil, which comprises nine municipalities: Campos dos Goytacazes, Macaé, São João da Barra, Conceição de Macabu, São Francisco de Itabapoana, Quissamã, São Fidélis, Carapebus, Cardoso Moreira. Methods: Information was for the year period 1999-2005 from the Live Birth Information Notification System, SINASC. Frequencies were calculated for the variables: municipality, year of notification, category of system affected, maternal age and affected gender. Results: Considering the category of system affected, year of notification and municipality, the cumulative number of notified birth defects was 425. Distributed by affected gender and maternal age, there were 440 notifications, without significant differences (Student t-test p = 0.2181). Prevalence of notified birth defects was 47/10,000 live births (mean annual frequency 0.46% ± 0.11%). The rate of birth defects in males (0.54) was higher than in females (0.46), but not significantly different from the expected values (c2 test pmales =0.7180; pfemales p = 0.5956). The most frequent birth defects involved the central nervous system (21% of all birth defects; 0.097% of all live births) and the musculoskeletal system (20.5% of all birth defects; 0.095% of all live births). The majority (63%) of affected children were born to women aged 20-34 years and the least (9.7%) to mothers aged 35-44 years. The majority of affected children were born in Campos dos Goytacazes (64%) and the least (0.7%) in Cardoso Moreira. Conclusions: The prevalence of birth defects for the Northern Region of the State is approximately half the rates reported by other studies in Brazil, including the city of Rio de Janeiro. Given that the distribution of all live births in the Northern Region of the State is indistinguishable from the National mean birth rates per maternal age distribution, the data point to a significant sub notification for the interior of the State.Introdução: As malformações congênitas constituem alterações simples ou múltiplas da estrutura, função e/ou metabolismo que resultam em incapacidade física ou mental, as causas mais freqüentes de morbidade e mortalidade infantil no mundo. A sua etiologia é diversa, podendo ser ou não de base genética. No Brasil aproximadamente 2 a 3% de todos os nascidos vivos são afetados por algum tipo de malformação. Contudo, variações em incidência em até 8% têm sido relatadas segundo o sexo, etnia e local de residência. Objetivos: Avaliar a ocorrência de defeitos congênitos na Região Norte Fluminense, que compreende nove municípios: Campos dos Goytacazes, Macaé, São João da Barra, Conceição de Macabu, São Francisco de Itabapoana, Quissamã, São Fidélis, Carapebus, Cardoso Moreira. Métodos: Foram utilizadas as informações relativas ao período 1999-2005 do Sistema de Informação sobre Nascidos Vivos, SINASC. Foram calculadas as freqüências para as variáveis: município, ano de notificação, categoria de sistema afetado, idade reprodutiva materna e sexo do acometido. Resultados: Em relação à categoria de sistema afetado, ano de notificação e município o número total de malformações notificadas foi 425. Segundo o sexo do acometido e a idade materna houve 440 notificações, sem diferenças significativas (teste t em par de Student p = 0,2181). A prevalência de malformações foi 47/10.000 nascidos vivos (freqüência média anual de 0,46% ± 0,11%). A taxa de defeitos congênitos para o sexo masculino (0,54) foi maior do que para o sexo feminino (0,46), mas não significativamente diferente do esperado (tese c2 pmasculino = 0,7180; pfeminino p = 0,5956). Os defeitos mais freqüentes envolveram os sistemas nervoso central (21% das notificações; 0,097% dos nascidos vivos) e osteomuscular (20,5% das notificações; 0,095% dos nascidos vivos). A maioria (63%) dos acometidos nasceu de mulheres na faixa etária 35-44 anos. Dentre os afetados, a maior freqüência (64%) ocorreu em Campos dos Goytacazes e a menor (0,7%) em Cardoso Moreira. Conclusões: A prevalência de malformações congênitas na Região Norte Fluminense é aproximadamente a metade das taxas relatadas em outros estudos no Brasil, incluindo a cidade de Rio de Janeiro. Uma vez que as taxas de natalidade por faixa etária materna na Região são indistinguíveis das médias nacionais os dados apontam para uma significativa subnotificação de acometidos para o interior do Estado de Rio de Janeiro.Faculdade de Medicina de Campos (FMC)2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.fmc.br/ojs/index.php/RCFMC/article/view/13710.29184/1980-7813.rcfmc.137.vol.3.n2.2008Scientific Journal of the Medical School of Campos; Vol. 3 No. 2 (2008); 11-18Revista Científica da Faculdade de Medicina de Campos; v. 3 n. 2 (2008); 11-181980-7813reponame:Revista Científica da Faculdade de Medicina de Camposinstname:Faculdade de Medicina de Campos (FMC)instacron:FMCporhttps://www.fmc.br/ojs/index.php/RCFMC/article/view/137/107Copyright (c) 2008 Revista Científica da Faculdade de Medicina de Camposinfo:eu-repo/semantics/openAccessFalleiro, Luciana VilarMedina-Acosta, Enrique2017-08-30T13:12:44Zoai:ojs.www.fmc.br:article/137Revistahttps://www.fmc.br/ojs/index.php/RCFMC/PRIhttps://www.fmc.br/ojs/index.php/RCFMC/oai||revista@fmc.br1980-78131980-7813opendoar:2017-08-30T13:12:44Revista Científica da Faculdade de Medicina de Campos - Faculdade de Medicina de Campos (FMC)false |
dc.title.none.fl_str_mv |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) Prevalência de malformações congênitas na Região Norte do Estado do Rio de Janeiro: uma avaliação das notificações de nascidos vivos (1999-2005) |
title |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) |
spellingShingle |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) Falleiro, Luciana Vilar idade materna malformação congênita prevalência SINASC birth defects congenital defe congenital defects maternal age prevalence SINASC |
title_short |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) |
title_full |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) |
title_fullStr |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) |
title_full_unstemmed |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) |
title_sort |
Prevalence of congenital birth defects in the Northern Region of the State of Rio de Janeiro, Brazil: an evaluation through life birth notifications (1999 to 2005) |
author |
Falleiro, Luciana Vilar |
author_facet |
Falleiro, Luciana Vilar Medina-Acosta, Enrique |
author_role |
author |
author2 |
Medina-Acosta, Enrique |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Falleiro, Luciana Vilar Medina-Acosta, Enrique |
dc.subject.por.fl_str_mv |
idade materna malformação congênita prevalência SINASC birth defects congenital defe congenital defects maternal age prevalence SINASC |
topic |
idade materna malformação congênita prevalência SINASC birth defects congenital defe congenital defects maternal age prevalence SINASC |
description |
Introduction: Birth defects constitute simple or multiple alterations of structure, function and/or metabolism that result in physical or mental disabilities, the leading causes of child morbidity and mortality worldwide. Its etiology is diverse and it may or not be genetic. In Brazil, approximately 2 to 3% of all live births are affected by some type of malformation. Nevertheless, variations by gender, ethnicity and place of residence up to 8% have been reported. Objectives: To evaluate the occurrence of birth defects in the Northern Region of the State of Rio de Janeiro, Brazil, which comprises nine municipalities: Campos dos Goytacazes, Macaé, São João da Barra, Conceição de Macabu, São Francisco de Itabapoana, Quissamã, São Fidélis, Carapebus, Cardoso Moreira. Methods: Information was for the year period 1999-2005 from the Live Birth Information Notification System, SINASC. Frequencies were calculated for the variables: municipality, year of notification, category of system affected, maternal age and affected gender. Results: Considering the category of system affected, year of notification and municipality, the cumulative number of notified birth defects was 425. Distributed by affected gender and maternal age, there were 440 notifications, without significant differences (Student t-test p = 0.2181). Prevalence of notified birth defects was 47/10,000 live births (mean annual frequency 0.46% ± 0.11%). The rate of birth defects in males (0.54) was higher than in females (0.46), but not significantly different from the expected values (c2 test pmales =0.7180; pfemales p = 0.5956). The most frequent birth defects involved the central nervous system (21% of all birth defects; 0.097% of all live births) and the musculoskeletal system (20.5% of all birth defects; 0.095% of all live births). The majority (63%) of affected children were born to women aged 20-34 years and the least (9.7%) to mothers aged 35-44 years. The majority of affected children were born in Campos dos Goytacazes (64%) and the least (0.7%) in Cardoso Moreira. Conclusions: The prevalence of birth defects for the Northern Region of the State is approximately half the rates reported by other studies in Brazil, including the city of Rio de Janeiro. Given that the distribution of all live births in the Northern Region of the State is indistinguishable from the National mean birth rates per maternal age distribution, the data point to a significant sub notification for the interior of the State. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.fmc.br/ojs/index.php/RCFMC/article/view/137 10.29184/1980-7813.rcfmc.137.vol.3.n2.2008 |
url |
https://www.fmc.br/ojs/index.php/RCFMC/article/view/137 |
identifier_str_mv |
10.29184/1980-7813.rcfmc.137.vol.3.n2.2008 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.fmc.br/ojs/index.php/RCFMC/article/view/137/107 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2008 Revista Científica da Faculdade de Medicina de Campos info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2008 Revista Científica da Faculdade de Medicina de Campos |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Faculdade de Medicina de Campos (FMC) |
publisher.none.fl_str_mv |
Faculdade de Medicina de Campos (FMC) |
dc.source.none.fl_str_mv |
Scientific Journal of the Medical School of Campos; Vol. 3 No. 2 (2008); 11-18 Revista Científica da Faculdade de Medicina de Campos; v. 3 n. 2 (2008); 11-18 1980-7813 reponame:Revista Científica da Faculdade de Medicina de Campos instname:Faculdade de Medicina de Campos (FMC) instacron:FMC |
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Faculdade de Medicina de Campos (FMC) |
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FMC |
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FMC |
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Revista Científica da Faculdade de Medicina de Campos |
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Revista Científica da Faculdade de Medicina de Campos |
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Revista Científica da Faculdade de Medicina de Campos - Faculdade de Medicina de Campos (FMC) |
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