How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Dental Journal |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402018000600606 |
Resumo: | Abstract The aim of this paper is to systematically review the literature to estimate the overall prevalence of xerostomia/hyposalivation in epidemiological studies. An electronic search was carried out up to February 2018 with no language restrictions. A total of 5760 titles were screened and just twenty-nine papers were included in review and the meta-analysis after a two independently reviewers applied the selection criteria. Data were extracted from PubMed and Web of Science databases. Eligibility criteria included original investigations from observational population-based studies that reported the prevalence of xerostomia or data that allowed the calculation of prevalence of xerostomia and/or hyposalivation. Studies conducted in samples with specific health conditions, literature reviews, case reports and anthropological studies, as conferences or comments were excluded. Sample size, geographic location of the study, study design, age of the studied population, diagnosis methods, and evaluation criteria used to determine xerostomia e/or hyposalivation were extracted for meta-analysis and meta-regression. Multivariate meta-regression analysis was performed to explore heterogeneity among studies. The overall estimated prevalence of dry mouth was 22.0% (95%CI 17.0-26.0%). Higher prevalence of xerostomia was observed in studies conducted only with elderly people. Despite diverse approaches to the condition’s measurement, just over one in four people suffer from xerostomia, with higher rates observed among older people. Moreover, the measurement methods used currently may over- or underestimate xerostomia. These findings highlight the need for further work on existing and new clinical measure and will be useful to determine which one is more reliable in clinical and epidemiological perspectives. |
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How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimatesxerostomiadry mouthhyposalivationglobal prevalencesalivary functionAbstract The aim of this paper is to systematically review the literature to estimate the overall prevalence of xerostomia/hyposalivation in epidemiological studies. An electronic search was carried out up to February 2018 with no language restrictions. A total of 5760 titles were screened and just twenty-nine papers were included in review and the meta-analysis after a two independently reviewers applied the selection criteria. Data were extracted from PubMed and Web of Science databases. Eligibility criteria included original investigations from observational population-based studies that reported the prevalence of xerostomia or data that allowed the calculation of prevalence of xerostomia and/or hyposalivation. Studies conducted in samples with specific health conditions, literature reviews, case reports and anthropological studies, as conferences or comments were excluded. Sample size, geographic location of the study, study design, age of the studied population, diagnosis methods, and evaluation criteria used to determine xerostomia e/or hyposalivation were extracted for meta-analysis and meta-regression. Multivariate meta-regression analysis was performed to explore heterogeneity among studies. The overall estimated prevalence of dry mouth was 22.0% (95%CI 17.0-26.0%). Higher prevalence of xerostomia was observed in studies conducted only with elderly people. Despite diverse approaches to the condition’s measurement, just over one in four people suffer from xerostomia, with higher rates observed among older people. Moreover, the measurement methods used currently may over- or underestimate xerostomia. These findings highlight the need for further work on existing and new clinical measure and will be useful to determine which one is more reliable in clinical and epidemiological perspectives.Fundação Odontológica de Ribeirão Preto2018-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402018000600606Brazilian Dental Journal v.29 n.6 2018reponame:Brazilian Dental Journalinstname:Fundação Odontológica de Ribeirão Preto (FUNORP)instacron:FUNORP10.1590/0103-6440201802302info:eu-repo/semantics/openAccessAgostini,Bernardo AntonioCericato,Graziela OroSilveira,Ethieli Rodrigues daNascimento,Gustavo GiacomelliCosta,Francine dos SantosThomson,Willian MurrayDemarco,Flavio Fernandoeng2018-11-27T00:00:00Zoai:scielo:S0103-64402018000600606Revistahttps://www.scielo.br/j/bdj/https://old.scielo.br/oai/scielo-oai.phpbdj@forp.usp.br||sergio@fosjc.unesp.br1806-47600103-6440opendoar:2018-11-27T00:00Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP)false |
dc.title.none.fl_str_mv |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
title |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
spellingShingle |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates Agostini,Bernardo Antonio xerostomia dry mouth hyposalivation global prevalence salivary function |
title_short |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
title_full |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
title_fullStr |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
title_full_unstemmed |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
title_sort |
How Common is Dry Mouth? Systematic Review and Meta-Regression Analysis of Prevalence Estimates |
author |
Agostini,Bernardo Antonio |
author_facet |
Agostini,Bernardo Antonio Cericato,Graziela Oro Silveira,Ethieli Rodrigues da Nascimento,Gustavo Giacomelli Costa,Francine dos Santos Thomson,Willian Murray Demarco,Flavio Fernando |
author_role |
author |
author2 |
Cericato,Graziela Oro Silveira,Ethieli Rodrigues da Nascimento,Gustavo Giacomelli Costa,Francine dos Santos Thomson,Willian Murray Demarco,Flavio Fernando |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Agostini,Bernardo Antonio Cericato,Graziela Oro Silveira,Ethieli Rodrigues da Nascimento,Gustavo Giacomelli Costa,Francine dos Santos Thomson,Willian Murray Demarco,Flavio Fernando |
dc.subject.por.fl_str_mv |
xerostomia dry mouth hyposalivation global prevalence salivary function |
topic |
xerostomia dry mouth hyposalivation global prevalence salivary function |
description |
Abstract The aim of this paper is to systematically review the literature to estimate the overall prevalence of xerostomia/hyposalivation in epidemiological studies. An electronic search was carried out up to February 2018 with no language restrictions. A total of 5760 titles were screened and just twenty-nine papers were included in review and the meta-analysis after a two independently reviewers applied the selection criteria. Data were extracted from PubMed and Web of Science databases. Eligibility criteria included original investigations from observational population-based studies that reported the prevalence of xerostomia or data that allowed the calculation of prevalence of xerostomia and/or hyposalivation. Studies conducted in samples with specific health conditions, literature reviews, case reports and anthropological studies, as conferences or comments were excluded. Sample size, geographic location of the study, study design, age of the studied population, diagnosis methods, and evaluation criteria used to determine xerostomia e/or hyposalivation were extracted for meta-analysis and meta-regression. Multivariate meta-regression analysis was performed to explore heterogeneity among studies. The overall estimated prevalence of dry mouth was 22.0% (95%CI 17.0-26.0%). Higher prevalence of xerostomia was observed in studies conducted only with elderly people. Despite diverse approaches to the condition’s measurement, just over one in four people suffer from xerostomia, with higher rates observed among older people. Moreover, the measurement methods used currently may over- or underestimate xerostomia. These findings highlight the need for further work on existing and new clinical measure and will be useful to determine which one is more reliable in clinical and epidemiological perspectives. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402018000600606 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402018000600606 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0103-6440201802302 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Fundação Odontológica de Ribeirão Preto |
publisher.none.fl_str_mv |
Fundação Odontológica de Ribeirão Preto |
dc.source.none.fl_str_mv |
Brazilian Dental Journal v.29 n.6 2018 reponame:Brazilian Dental Journal instname:Fundação Odontológica de Ribeirão Preto (FUNORP) instacron:FUNORP |
instname_str |
Fundação Odontológica de Ribeirão Preto (FUNORP) |
instacron_str |
FUNORP |
institution |
FUNORP |
reponame_str |
Brazilian Dental Journal |
collection |
Brazilian Dental Journal |
repository.name.fl_str_mv |
Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP) |
repository.mail.fl_str_mv |
bdj@forp.usp.br||sergio@fosjc.unesp.br |
_version_ |
1754204095325929472 |