Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Dental Journal |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402008000200014 |
Resumo: | McCune-Albright syndrome is characterized by the triad café-au-lait cutaneous spots, polyostotic fibrous dysplasia and endocrinopathies. This article presents two cases of McCune-Albright syndrome in a middle-aged woman and a young girl. Both patients presented café-au-lait spots on the face and other parts of the body and expansion of the mandible with radiopaque-radiolucent areas with ground-glass radiographic appearance, and were diagnosed as having fibrous dysplasia and endocrine disorders. The patient of Case 1 had fibrous dysplasia on the upper and lower limbs, thorax, face and cranium, early puberty, hyperglycemia, hyperthyroidism and high serum alkaline phosphatase levels. The patient of Case 2 presented lesions on the upper limbs and evident endocrine disorders. In both cases presented in this article, the initial exam was made because of the mandibular lesion. However, a diagnosis of fibrous dysplasia must lead to investigation of the involvement of other bones, characterizing polyostotic fibrous dysplasia, which is manifested in a number of diseases. An accurate differential diagnosis is mandatory to determine the best treatment approach for each case. |
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Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two casesMcCune-Albright syndromepolyostotic fibrous dysplasiacafé-au-lait skin hyperpigmentationMcCune-Albright syndrome is characterized by the triad café-au-lait cutaneous spots, polyostotic fibrous dysplasia and endocrinopathies. This article presents two cases of McCune-Albright syndrome in a middle-aged woman and a young girl. Both patients presented café-au-lait spots on the face and other parts of the body and expansion of the mandible with radiopaque-radiolucent areas with ground-glass radiographic appearance, and were diagnosed as having fibrous dysplasia and endocrine disorders. The patient of Case 1 had fibrous dysplasia on the upper and lower limbs, thorax, face and cranium, early puberty, hyperglycemia, hyperthyroidism and high serum alkaline phosphatase levels. The patient of Case 2 presented lesions on the upper limbs and evident endocrine disorders. In both cases presented in this article, the initial exam was made because of the mandibular lesion. However, a diagnosis of fibrous dysplasia must lead to investigation of the involvement of other bones, characterizing polyostotic fibrous dysplasia, which is manifested in a number of diseases. An accurate differential diagnosis is mandatory to determine the best treatment approach for each case.Fundação Odontológica de Ribeirão Preto2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402008000200014Brazilian Dental Journal v.19 n.2 2008reponame:Brazilian Dental Journalinstname:Fundação Odontológica de Ribeirão Preto (FUNORP)instacron:FUNORP10.1590/S0103-64402008000200014info:eu-repo/semantics/openAccessXavier,Samuel PorfírioRibeiro,Michel CamposSicchieri,Luciana GonçalvesBrentegani,Luiz GuilhermeLacerda,Suzie Aparecidaeng2008-06-12T00:00:00Zoai:scielo:S0103-64402008000200014Revistahttps://www.scielo.br/j/bdj/https://old.scielo.br/oai/scielo-oai.phpbdj@forp.usp.br||sergio@fosjc.unesp.br1806-47600103-6440opendoar:2008-06-12T00:00Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP)false |
dc.title.none.fl_str_mv |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
title |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
spellingShingle |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases Xavier,Samuel Porfírio McCune-Albright syndrome polyostotic fibrous dysplasia café-au-lait skin hyperpigmentation |
title_short |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
title_full |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
title_fullStr |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
title_full_unstemmed |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
title_sort |
Clinical, microscopic and imaging findings associated to Mccune-Albright syndrome: report of two cases |
author |
Xavier,Samuel Porfírio |
author_facet |
Xavier,Samuel Porfírio Ribeiro,Michel Campos Sicchieri,Luciana Gonçalves Brentegani,Luiz Guilherme Lacerda,Suzie Aparecida |
author_role |
author |
author2 |
Ribeiro,Michel Campos Sicchieri,Luciana Gonçalves Brentegani,Luiz Guilherme Lacerda,Suzie Aparecida |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Xavier,Samuel Porfírio Ribeiro,Michel Campos Sicchieri,Luciana Gonçalves Brentegani,Luiz Guilherme Lacerda,Suzie Aparecida |
dc.subject.por.fl_str_mv |
McCune-Albright syndrome polyostotic fibrous dysplasia café-au-lait skin hyperpigmentation |
topic |
McCune-Albright syndrome polyostotic fibrous dysplasia café-au-lait skin hyperpigmentation |
description |
McCune-Albright syndrome is characterized by the triad café-au-lait cutaneous spots, polyostotic fibrous dysplasia and endocrinopathies. This article presents two cases of McCune-Albright syndrome in a middle-aged woman and a young girl. Both patients presented café-au-lait spots on the face and other parts of the body and expansion of the mandible with radiopaque-radiolucent areas with ground-glass radiographic appearance, and were diagnosed as having fibrous dysplasia and endocrine disorders. The patient of Case 1 had fibrous dysplasia on the upper and lower limbs, thorax, face and cranium, early puberty, hyperglycemia, hyperthyroidism and high serum alkaline phosphatase levels. The patient of Case 2 presented lesions on the upper limbs and evident endocrine disorders. In both cases presented in this article, the initial exam was made because of the mandibular lesion. However, a diagnosis of fibrous dysplasia must lead to investigation of the involvement of other bones, characterizing polyostotic fibrous dysplasia, which is manifested in a number of diseases. An accurate differential diagnosis is mandatory to determine the best treatment approach for each case. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402008000200014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402008000200014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-64402008000200014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Fundação Odontológica de Ribeirão Preto |
publisher.none.fl_str_mv |
Fundação Odontológica de Ribeirão Preto |
dc.source.none.fl_str_mv |
Brazilian Dental Journal v.19 n.2 2008 reponame:Brazilian Dental Journal instname:Fundação Odontológica de Ribeirão Preto (FUNORP) instacron:FUNORP |
instname_str |
Fundação Odontológica de Ribeirão Preto (FUNORP) |
instacron_str |
FUNORP |
institution |
FUNORP |
reponame_str |
Brazilian Dental Journal |
collection |
Brazilian Dental Journal |
repository.name.fl_str_mv |
Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto (FUNORP) |
repository.mail.fl_str_mv |
bdj@forp.usp.br||sergio@fosjc.unesp.br |
_version_ |
1754204090869481472 |