Hepatitis G virus and coinfection in seropositive for human immunodeficiency virus - review

• Autor(a) principal: Mota, Luísa Dias da
• Data de Publicação: 2013
• Outros Autores: Germano, Fabiana Nunes, Barral, Maria Fernanda Martínez, Silva, Naylê Maria Oliveira da, Martinez, Ana Maria Barral de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da FURG (RI FURG)
• Texto Completo: http://repositorio.furg.br/handle/1/7020
• topic: GB virus C; HIV; Anti-HIV agents; Vírus GB C; Agentes Anti-HIV; HIV-1

Fundamentation: Hepatitis G Virus (GBV-C) is a very common with worldwide distribution virus, although there are few studies about it. Most studies relate GBV-C coinfection with HIV as a protective factor. Objective: the objective of this study was to conduct a literature review about hepatitis G virus and its coinfection in patients with HIV. Methods: To perform this systematic review we used the electronic databases MEDLINE (National Library of Medicine), LILACS (Latin American and Caribbean Health Sciences) and SciELO (Scientific Electronic Library Online), using the following keywords: GB virus C anti-HIV, HIV. Results: At the end of the electronic research 55 articles were selected, including observational studies, experimental and literature reviews. Although the protective effect of GBV-C is still controversial in the literature, scientific research indicate that GBV-C brings an improvement in the prognosis of patients infected with HIV. Some studies even show an increase in CD4 + T cells count. These evidences and the fact that GBV-C is a virus with a wide distribution in the world population show the relevance of studies. Conclusion: Therefore, additional research become necessary for a better understanding of the virus as an hepatitis agent, as well as epidemiological surveys from different regions and studies about its association with HIV.