Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FURG (RI FURG) |
Texto Completo: | http://repositorio.furg.br/handle/1/7038 |
Resumo: | Summary: We estimated the prevalence of hepatitis C (HCV) infection and associated risk factors in 750 individuals attendING at the voluntary counseling and Testing Center of Rio Grande (VCT/RG), in Southern Brazil, and identified viral genotypes. Demographic data and risk factors for HCV transmission were also collected and analysed. Anti-HCV-antibody-positive individuals were tested for HCV-RNA and genotyped by sequencing the 50 untranslated region of the viral genome. Prevalence estimates of anti-HCV and HCVRNA were 6% and 5.5%, respectively. We identified genotypes 1 (67%), 2 (2%) and 3 (31%); the latter was more prevalent than in other regions of Brazil. Anti-HCV prevalence in VCT/RG users was similar to previous reports. Age, previous blood transfusion, sexual orientation and injecting drug use were independent predictors of HCV infection. The presence of multiple risk factors was also associated with a higher risk for HCV infection. HCV genotype was not associated with any variable analysed in this study. |
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Germano, Fabiana NunesSantos, Cristina Araújo dosHonscha, GuntherStrasburg, Aline da CruzGabbi, Bruno SmidtMendoza-Sassi, Raúl Andrés2017-01-26T20:31:35Z2017-01-26T20:31:35Z2010GERMANO, Fabiana Nunes et al. Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes. International Journal of STD & AIDS, v. 21, n. 7, p. 466-471, 2010. Disponível em:<http://journals.sagepub.com/doi/pdf/10.1258/ijsa.2009.009089 >. Acesso em: 25 jan. 2017.09564624http://repositorio.furg.br/handle/1/703810.1258/ijsa.2009.009089Summary: We estimated the prevalence of hepatitis C (HCV) infection and associated risk factors in 750 individuals attendING at the voluntary counseling and Testing Center of Rio Grande (VCT/RG), in Southern Brazil, and identified viral genotypes. Demographic data and risk factors for HCV transmission were also collected and analysed. Anti-HCV-antibody-positive individuals were tested for HCV-RNA and genotyped by sequencing the 50 untranslated region of the viral genome. Prevalence estimates of anti-HCV and HCVRNA were 6% and 5.5%, respectively. We identified genotypes 1 (67%), 2 (2%) and 3 (31%); the latter was more prevalent than in other regions of Brazil. Anti-HCV prevalence in VCT/RG users was similar to previous reports. Age, previous blood transfusion, sexual orientation and injecting drug use were independent predictors of HCV infection. The presence of multiple risk factors was also associated with a higher risk for HCV infection. HCV genotype was not associated with any variable analysed in this study.engHCVGenotypePrevalenceRisk factorsSouthern BrazilPrevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FURG (RI FURG)instname:Universidade Federal do Rio Grande (FURG)instacron:FURGORIGINALijsa%2E2009%2E009089.pdfijsa%2E2009%2E009089.pdfapplication/pdf122518https://repositorio.furg.br/bitstream/1/7038/1/ijsa%252E2009%252E009089.pdfb530820eec8c4065c0a339beed9d2c07MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.furg.br/bitstream/1/7038/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52open access1/70382022-10-20 16:51:17.057open accessoai:repositorio.furg.br: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Repositório InstitucionalPUBhttps://repositorio.furg.br/oai/request || http://200.19.254.174/oai/requestopendoar:2022-10-20T19:51:17Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)false |
dc.title.pt_BR.fl_str_mv |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
title |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
spellingShingle |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes Germano, Fabiana Nunes HCV Genotype Prevalence Risk factors Southern Brazil |
title_short |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
title_full |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
title_fullStr |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
title_full_unstemmed |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
title_sort |
Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes |
author |
Germano, Fabiana Nunes |
author_facet |
Germano, Fabiana Nunes Santos, Cristina Araújo dos Honscha, Gunther Strasburg, Aline da Cruz Gabbi, Bruno Smidt Mendoza-Sassi, Raúl Andrés |
author_role |
author |
author2 |
Santos, Cristina Araújo dos Honscha, Gunther Strasburg, Aline da Cruz Gabbi, Bruno Smidt Mendoza-Sassi, Raúl Andrés |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Germano, Fabiana Nunes Santos, Cristina Araújo dos Honscha, Gunther Strasburg, Aline da Cruz Gabbi, Bruno Smidt Mendoza-Sassi, Raúl Andrés |
dc.subject.por.fl_str_mv |
HCV Genotype Prevalence Risk factors Southern Brazil |
topic |
HCV Genotype Prevalence Risk factors Southern Brazil |
description |
Summary: We estimated the prevalence of hepatitis C (HCV) infection and associated risk factors in 750 individuals attendING at the voluntary counseling and Testing Center of Rio Grande (VCT/RG), in Southern Brazil, and identified viral genotypes. Demographic data and risk factors for HCV transmission were also collected and analysed. Anti-HCV-antibody-positive individuals were tested for HCV-RNA and genotyped by sequencing the 50 untranslated region of the viral genome. Prevalence estimates of anti-HCV and HCVRNA were 6% and 5.5%, respectively. We identified genotypes 1 (67%), 2 (2%) and 3 (31%); the latter was more prevalent than in other regions of Brazil. Anti-HCV prevalence in VCT/RG users was similar to previous reports. Age, previous blood transfusion, sexual orientation and injecting drug use were independent predictors of HCV infection. The presence of multiple risk factors was also associated with a higher risk for HCV infection. HCV genotype was not associated with any variable analysed in this study. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2017-01-26T20:31:35Z |
dc.date.available.fl_str_mv |
2017-01-26T20:31:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GERMANO, Fabiana Nunes et al. Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes. International Journal of STD & AIDS, v. 21, n. 7, p. 466-471, 2010. Disponível em:<http://journals.sagepub.com/doi/pdf/10.1258/ijsa.2009.009089 >. Acesso em: 25 jan. 2017. |
dc.identifier.uri.fl_str_mv |
http://repositorio.furg.br/handle/1/7038 |
dc.identifier.issn.none.fl_str_mv |
09564624 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.1258/ijsa.2009.009089 |
identifier_str_mv |
GERMANO, Fabiana Nunes et al. Prevalence of hepatitis C virus among users attending a voluntary testing centre in Rio Grande, Southern Brazil: predictive factors and hepatitis C virus genotypes. International Journal of STD & AIDS, v. 21, n. 7, p. 466-471, 2010. Disponível em:<http://journals.sagepub.com/doi/pdf/10.1258/ijsa.2009.009089 >. Acesso em: 25 jan. 2017. 09564624 10.1258/ijsa.2009.009089 |
url |
http://repositorio.furg.br/handle/1/7038 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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reponame:Repositório Institucional da FURG (RI FURG) instname:Universidade Federal do Rio Grande (FURG) instacron:FURG |
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Universidade Federal do Rio Grande (FURG) |
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