Diagnosis and treatment of cervical cancer during pregnancy
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FURG (RI FURG) |
Texto Completo: | http://repositorio.furg.br/handle/1/2613 http://dx.doi.org/10.1590/S1516-31802009000600008 |
Resumo: | CONTEXT AND OBJECTIVE: One third of all cervical carcinomas occur during the reproductive period. Cervical carcinoma is the second greatest cause of death due to cancer during this phase. The estimated frequency of cervical cancer during pregnancy is one case for every 1,000 to 5,000 pregnancies. The aim here was to provide information about the difficulties in diagnosing and managing cervical neoplasia during pregnancy. MATERIALS: A systematic review of the literature was undertaken through the PubMed, Cochrane, Excerpta Medica (Embase), Literatura Latino Americana e do Caribe em Ciências da Saúde (Lilacs) and Scientific Electronic Library Online (SciELO) databases, using the following words: pregnancy, cervical cancer, diagnosis and management. RESULTS: There was a consensus in the literature regarding diagnosis of cervical carcinoma and management of preneoplastic lesions during pregnancy. However, for management of invasive carcinoma, there was great divergence regarding the gestational age taken as the limit for observation rather than immediate treatment. CONCLUSION: All patients with cytological abnormalities should undergo colposcopy, which will indicate and guide biopsy. Conization is reserved for patients with suspected invasion. High-grade lesions should be monitored during pregnancy and reevaluated after delivery. In cases of invasive carcinoma detected up to the 12th week of pregnancy, patient treatment is prioritized. Regarding diagnoses made during the second trimester, fetal pulmonary maturity can be awaited, and the use of chemotherapy to stabilize the disease until the time of delivery appears to be viable. |
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Diagnosis and treatment of cervical cancer during pregnancyDiagnóstico e tratamento do câncer do colo uterino durante a gestaçãoUterine cervical neoplasmsUterine cervical dysplasiaDiagnosisTreatment effectivenessTreatment protocolsPregnancyNeoplasia do colo do úteroDisplasia do colo do úteroDiagnósticoResultado de tratamentoProtocolos clínicosGravidezCONTEXT AND OBJECTIVE: One third of all cervical carcinomas occur during the reproductive period. Cervical carcinoma is the second greatest cause of death due to cancer during this phase. The estimated frequency of cervical cancer during pregnancy is one case for every 1,000 to 5,000 pregnancies. The aim here was to provide information about the difficulties in diagnosing and managing cervical neoplasia during pregnancy. MATERIALS: A systematic review of the literature was undertaken through the PubMed, Cochrane, Excerpta Medica (Embase), Literatura Latino Americana e do Caribe em Ciências da Saúde (Lilacs) and Scientific Electronic Library Online (SciELO) databases, using the following words: pregnancy, cervical cancer, diagnosis and management. RESULTS: There was a consensus in the literature regarding diagnosis of cervical carcinoma and management of preneoplastic lesions during pregnancy. However, for management of invasive carcinoma, there was great divergence regarding the gestational age taken as the limit for observation rather than immediate treatment. CONCLUSION: All patients with cytological abnormalities should undergo colposcopy, which will indicate and guide biopsy. Conization is reserved for patients with suspected invasion. High-grade lesions should be monitored during pregnancy and reevaluated after delivery. In cases of invasive carcinoma detected up to the 12th week of pregnancy, patient treatment is prioritized. Regarding diagnoses made during the second trimester, fetal pulmonary maturity can be awaited, and the use of chemotherapy to stabilize the disease until the time of delivery appears to be viable.CONTEXTO E OBJETIVO: Um terço dos carcinomas de colo ocorrem no período reprodutivo, sendo que esta é a segunda causa de morte por câncer nessa fase. A freqüência estimada do carcinoma de colo uterino na gravidez é de um caso para cada 1.000 a 5.000 gestações. O objetivo foi informar sobre as dificuldades frente ao diagnóstico e manejo da neoplasia cervical durante a gravidez. MATERIAIS E MÉTODOS: Revisão sistemática da literatura foi realizada no PubMed, Cochrane, Excerpta Medica (Embase), Literatura Latino Americana e do Caribe em Ciências da Saúde (Lilacs) and Scientific Electronic Library Online (SciELO), usando as seguintes palavras: gestação, câncer cervical, diagnóstico e manejo. RESULTADOS: A literatura apresenta consenso quanto ao diagnóstico do carcinoma cervical e a conduta das lesões pré-neoplásicas durante a gestação. No manejo do carcinoma invasor há grande divergência quanto à idade gestacional considerada como limite para a adoção da observação em vez do tratamento imediato. CONCLUSÃO: Toda paciente com citologia alterada deve realizar colposcopia, a qual indicará e a biópsia. A conização é reservada para pacientes com suspeita de invasão. As lesões de alto grau devem ser acompanhadas durante a gestação e reavaliadas após o parto. Em casos de carcinoma invasor em gestantes com até 12 semanas o tratamento da paciente é priorizado. Nos diagnósticos ocorridos no segundo trimestre, pode-se aguardar a maturidade pulmonar fetal e o uso da quimioterapia para estabilizar a doença até o momento do parto parece ser viável.2012-10-05T13:43:12Z2012-10-05T13:43:12Z2009info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfGONÇALVES, Carla Vitola et al. Diagnosis and treatment of cervical cancer during pregnancy. São Paulo Medical Journal, São Paulo, v. 127, n. 6, p. 359-365, 2009. Disponível em: <http://www.scielo.br/pdf/spmj/v127n6/08.pdf>. Acesso em: 24 ago. 2012.http://repositorio.furg.br/handle/1/2613http://dx.doi.org/10.1590/S1516-31802009000600008engGonçalves, Carla VitolaDuarte, GeraldoCosta, Juvenal Soares Dias daMarcolin, Alessandra CristinaBianchi, Mônica SteiglederDias, Daison Nelson FerreiraLima, Luis Cláudio de Velleca einfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FURG (RI FURG)instname:Universidade Federal do Rio Grande (FURG)instacron:FURG2021-01-22T17:19:00Zoai:repositorio.furg.br:1/2613Repositório InstitucionalPUBhttps://repositorio.furg.br/oai/request || http://200.19.254.174/oai/requestopendoar:2021-01-22T17:19Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)false |
dc.title.none.fl_str_mv |
Diagnosis and treatment of cervical cancer during pregnancy Diagnóstico e tratamento do câncer do colo uterino durante a gestação |
title |
Diagnosis and treatment of cervical cancer during pregnancy |
spellingShingle |
Diagnosis and treatment of cervical cancer during pregnancy Gonçalves, Carla Vitola Uterine cervical neoplasms Uterine cervical dysplasia Diagnosis Treatment effectiveness Treatment protocols Pregnancy Neoplasia do colo do útero Displasia do colo do útero Diagnóstico Resultado de tratamento Protocolos clínicos Gravidez |
title_short |
Diagnosis and treatment of cervical cancer during pregnancy |
title_full |
Diagnosis and treatment of cervical cancer during pregnancy |
title_fullStr |
Diagnosis and treatment of cervical cancer during pregnancy |
title_full_unstemmed |
Diagnosis and treatment of cervical cancer during pregnancy |
title_sort |
Diagnosis and treatment of cervical cancer during pregnancy |
author |
Gonçalves, Carla Vitola |
author_facet |
Gonçalves, Carla Vitola Duarte, Geraldo Costa, Juvenal Soares Dias da Marcolin, Alessandra Cristina Bianchi, Mônica Steigleder Dias, Daison Nelson Ferreira Lima, Luis Cláudio de Velleca e |
author_role |
author |
author2 |
Duarte, Geraldo Costa, Juvenal Soares Dias da Marcolin, Alessandra Cristina Bianchi, Mônica Steigleder Dias, Daison Nelson Ferreira Lima, Luis Cláudio de Velleca e |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Gonçalves, Carla Vitola Duarte, Geraldo Costa, Juvenal Soares Dias da Marcolin, Alessandra Cristina Bianchi, Mônica Steigleder Dias, Daison Nelson Ferreira Lima, Luis Cláudio de Velleca e |
dc.subject.por.fl_str_mv |
Uterine cervical neoplasms Uterine cervical dysplasia Diagnosis Treatment effectiveness Treatment protocols Pregnancy Neoplasia do colo do útero Displasia do colo do útero Diagnóstico Resultado de tratamento Protocolos clínicos Gravidez |
topic |
Uterine cervical neoplasms Uterine cervical dysplasia Diagnosis Treatment effectiveness Treatment protocols Pregnancy Neoplasia do colo do útero Displasia do colo do útero Diagnóstico Resultado de tratamento Protocolos clínicos Gravidez |
description |
CONTEXT AND OBJECTIVE: One third of all cervical carcinomas occur during the reproductive period. Cervical carcinoma is the second greatest cause of death due to cancer during this phase. The estimated frequency of cervical cancer during pregnancy is one case for every 1,000 to 5,000 pregnancies. The aim here was to provide information about the difficulties in diagnosing and managing cervical neoplasia during pregnancy. MATERIALS: A systematic review of the literature was undertaken through the PubMed, Cochrane, Excerpta Medica (Embase), Literatura Latino Americana e do Caribe em Ciências da Saúde (Lilacs) and Scientific Electronic Library Online (SciELO) databases, using the following words: pregnancy, cervical cancer, diagnosis and management. RESULTS: There was a consensus in the literature regarding diagnosis of cervical carcinoma and management of preneoplastic lesions during pregnancy. However, for management of invasive carcinoma, there was great divergence regarding the gestational age taken as the limit for observation rather than immediate treatment. CONCLUSION: All patients with cytological abnormalities should undergo colposcopy, which will indicate and guide biopsy. Conization is reserved for patients with suspected invasion. High-grade lesions should be monitored during pregnancy and reevaluated after delivery. In cases of invasive carcinoma detected up to the 12th week of pregnancy, patient treatment is prioritized. Regarding diagnoses made during the second trimester, fetal pulmonary maturity can be awaited, and the use of chemotherapy to stabilize the disease until the time of delivery appears to be viable. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009 2012-10-05T13:43:12Z 2012-10-05T13:43:12Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
GONÇALVES, Carla Vitola et al. Diagnosis and treatment of cervical cancer during pregnancy. São Paulo Medical Journal, São Paulo, v. 127, n. 6, p. 359-365, 2009. Disponível em: <http://www.scielo.br/pdf/spmj/v127n6/08.pdf>. Acesso em: 24 ago. 2012. http://repositorio.furg.br/handle/1/2613 http://dx.doi.org/10.1590/S1516-31802009000600008 |
identifier_str_mv |
GONÇALVES, Carla Vitola et al. Diagnosis and treatment of cervical cancer during pregnancy. São Paulo Medical Journal, São Paulo, v. 127, n. 6, p. 359-365, 2009. Disponível em: <http://www.scielo.br/pdf/spmj/v127n6/08.pdf>. Acesso em: 24 ago. 2012. |
url |
http://repositorio.furg.br/handle/1/2613 http://dx.doi.org/10.1590/S1516-31802009000600008 |
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eng |
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eng |
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openAccess |
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Universidade Federal do Rio Grande (FURG) |
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Repositório Institucional da FURG (RI FURG) |
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Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG) |
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