Current Trends in Effectiveness and Mechanisms of Action: A Systematic Review on the Use of GLP-1 Analogs in the Treatment of Obesity.

• Autor(a) principal: Silva, Bruna de Aquino Morais da
• Data de Publicação: 2023
• Outros Autores: Moura Vasconcelos, José Lucas, Azevedo, Leonardo Dias, Alves, Ana Clara Sertão, Marques, Anderson Almeida, Martins, Danielle Idelfonso Bottentuit, Santos Neto, Edvard José dos, Gonçalves, Emili Mariane Machado, Ribeiro, Géssica Lima, Santos, Julia de Souza Ferreira dos, Novaes, Marcio Ryan Araújo de, Gondim, Rafaela Magalhães, Giácomo, Rafaella Cançado Constantino de, Oliveira, Roberta Helena Marques de, Torres, Thaís da Silva, Melo, Vanessa Avelar Alcântara, Venuto, Vinycius Victor Ferreira
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/976
• topic: Obesidade; Agonistas do GLP-1; Tratamento

This work presents a systematic review on current trends in the effectiveness and mechanisms of action of GLP-1 analogs in the treatment of obesity. The introduction highlights the growing prevalence of obesity as a global public health challenge, positioning GLP-1 analogs as a promising approach. The methodology describes the formulation of the research question, study selection criteria, data extraction, and the analysis of study quality. The results emphasize the efficacy of these analogs in weight reduction, explore the neurobiological mechanisms involved, and demonstrate improvements in obesity-related comorbidities. The conclusion underscores the consistency of the reviewed evidence and the need for further research to optimize personalized therapeutic approaches.