Contemporary Views on Treatments for Depression: An Analysis of Recent Literature

• Autor(a) principal: Pereira Levada, Leonardo
• Data de Publicação: 2024
• Outros Autores: Pereira Cruz , Thomás, Letícia De Souza Barbosa, Júlia, de Assis França, Camila, Freitas Santos, Amanda, Sanches de Oliveira , Samanttha, Victoria Dantas Barros, Maria, Ferreira da Costa, Lucas, Santos Costa Lopes, Janaína, César Cota de Castro, Arthur, Tambosi Baseman, Guilherme, Dias Bonfim, Ítalo, Alves da Cunha, Mariana, Rodrigues Melo, Marcela, Moraes Guimarães, Eduardo, Alves Silva, Carlos
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1876
• topic: Depressão; tratamento; microbiota

The article examines a variety of recent advancements and therapeutic perspectives in the treatment of major depression (MDD), from traditional methods to new pharmacological and non-pharmacological approaches, including the impact of the gut-brain-microbiota axis. It discusses the role of tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs), as well as new therapeutic targets such as ketamine and psychedelics. Non-pharmacological therapies such as phototherapy, repetitive transcranial magnetic stimulation (rTMS), psychological intervention, and acupuncture are explored. Psilocybin is considered a potential therapeutic option, as well as the role of probiotics in modulating the gut microbiome. However, the need for controlled clinical trials to evaluate the efficacy and safety of these approaches before widespread adoption in clinical practice is emphasized, highlighting the importance of individualized treatment for each patient.