HIV pre-exposure prophylaxis (PrEP) as a combined prevention strategy and its clinical effectiveness: An integrated literature review.

• Autor(a) principal: Teixeira, Vanessa Cristina
• Data de Publicação: 2023
• Outros Autores: Figuerêdo Almeida, Ana Beatriz, Santos Reis, Allana, Matos Nunes, Arthur, Guedes Mota, Ester, Araújo Alves, Gabriel, Batista Ledo Martins, Gabriela Regina, Nunes Gomes, João Eduardo, Oliveira Tanajura, Maria Raniere, Ferreira Agra de Alencar, Maria Vitória, Zabam de Azevedo, Nicholas, Pessoa Silva Leite, Rafael, Teixeira Lima, Renata, Gonçalves Mota, Roberta, D'Ávila Barbosa Cruz, Teresa
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/966
• topic: PrEP; Profilaxia Pré-Exposição; HIV; Vulnerabilidade; PrEP; HIV; Vulnerability; Pre-Exposure Prophylaxis

This study aims to highlight the importance of Pre-Exposure Prophylaxis (PrEP) as an essential part of the combined HIV prevention strategy. To this end, an integrative review was conducted from June to September 2023, with research carried out in the SciELO and PubMed databases, using descriptors such as "PrEP/Pre-Exposure Prophylaxis", "HIV", "profilaxis/prophylaxis" and "effectiveness." The initial search resulted in 42 articles, which were subsequently subjected to rigorous selection criteria, resulting in the choice of 30 relevant articles. After applying the selection criteria, the 30 selected articles were subjected to a thorough reading by all members of the research team, aiming to collect effectiveness data. Seven large studies that evaluated the effectiveness of PrEP were identified and represented in a unified table, addressing the thematic categories of daily and on-demand pre-exposure prophylaxis. This made these studies easier to view and understand, providing a comprehensive view of PrEP effectiveness in different contexts. In summary, PrEP represents a significant advance in HIV prevention and plays a fundamental role in the fight against the epidemic. However, your success is intrinsically linked to awareness, education and ongoing support. Furthermore, PrEP must be integrated with other prevention strategies to optimize its impact in reducing the spread of HIV. The challenge now lies in ensuring equitable and effective access to PrEP, especially for vulnerable populations, in order to achieve goals related to ending the HIV epidemic. Consequently, PrEP plays a crucial role in the evolution of HIV prevention and the search for a future free from this epidemic.