Production of aqueous solutions from medicinal plants with anti-parasitic activity.

• Autor(a) principal: Aquino Alves, Maria Heloísa
• Data de Publicação: 2024
• Outros Autores: da Silva, Maria Clara, da Silva, Matheus Givanildo, de Lima Tiburcio, João Wictor, de Lima Sá Teles, Eduarda, Souza Guinho, Gleiciane Adrielli, da Silva, Gustavo Henrique, Muller Zigmundo da Silva Leite, Alexandre, Torres de Melo, Maria Luisa, Teixeira Macêdo, Nathalya, Quirino Alves, Gabriela, Pereira Cordeiro, Risonildo
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1168
• topic: Plantas Medicinais; Medicamento Fitoterápico; Parasitos; Toxicidade; Métodos Terapêuticos Complementares; Medicinal Plants; Herbal Medicine; Parasites; Toxicity; Complementary Therapeutic Methods; Plantas Medicinales; Medicina Herbal; Parásitos; Toxicidad; Métodos Terapéuticos Complementarios

The therapeutic use of medicinal plants is an ancient practice that has evolved with advances in science, making it possible to monitor their effects and promote the use of phytotherapics, even as a complementary therapy against parasitosis. In Brazil, national policies guarantee safe access to and the rational use of medicinal plants and phytotherapics, due to their effectiveness in primary health care. The aim of this study was to produce aqueous solutions with medicinal plants that are already part of people's daily lives to combat parasitic activity: Eucalyptus globulus, Mentha crispa, Petroselinum crispum, Coriandrum sativum and Punica granatum. To this end, dried hydroalcoholic crude extracts were produced using the maceration method and subsequent rotaevaporation for drying. Aqueous solutions were prepared at concentrations of 5mg/ml, 2.5mg/ml, 1.25mg/ml and 0.625mg/ml of all the extracts, after which the antiparasitic activity against Giardia sp and Entamoeba sp cysts was determined. To observe the toxicity of the solutions, the Artemia salina technique was used. The aqueous solutions of Eucalyptus globulus and Punica granatum showed activity against the microorganisms tested, the toxicity was significant for the Petroselinum crispum solutions and non-toxic for Punica granatum and Coriandrum sativum. All the aqueous solutions showed good stability. This highlights the potential and importance of research for therapeutic validation and improvement, allowing further studies to be carried out.