SYSTEMIC LUPUS ERYTHEMATOSUS, CONSIDERATIONS AND TREATMENTS: AN INTEGRATIVE REVIEW

• Autor(a) principal: Giovannini Sad Ribeiro, João Vítor
• Data de Publicação: 2024
• Outros Autores: Jatobá Barbosa, João Vitor, de Castro Honorato, Jordana, Brunetti Teles de Melo, Júlia, Drummond de Moura Miguez, Laura
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1742
• topic: Tratamento; Infecções; LES; Lúpus Eritematoso Sistêmico; Systemic Lupus Erythematosus; Treatment; Infections; SLE

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune and multisystemic inflammatory disease, with varied clinical presentations, with joint and skin involvement being the most common, and is most frequent in young and middle-aged women. Objective: This article aims to summarize and present current data and considerations about SLE, with a broader approach to its various treatments. Methods: Researches were made on Medline, Scielo and LILACS databases. Articles written in English, Spanish or Portuguese and published since 2016 were considered for this study. Those articles not related to the proposed theme and/or published before 2016 weren't considered. Furthermore, review articles were not used for the results. Results: Those analyzed articles pointed SLE as a disease  influenced by environmental and genetic factors, but its etiology is not clearly understood. As for treatments, the need to control the immune response is evident and this achievement depends on the effectiveness of the medication, patient´s response and what adverse effects they endure. Among those analyzed treatments, the results are promising  and it is necessary to individually evaluate the application of each one. Conclusion: It is important to highlight the relevance of different treatments, choosing the best one for each type of patient. However, more studies are needed to fully comprehend the condition of SLE and improve patient management and treatment.