Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action.
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Implantology and Health Sciences |
Texto Completo: | https://bjihs.emnuvens.com.br/bjihs/article/view/1291 |
Resumo: | This paper conducts a comprehensive literature review on the role of antidepressants in the treatment of anxiety. The analysis includes controlled clinical trials and systematic reviews addressing the efficacy of different classes of antidepressants, with a primary focus on Selective Serotonin Reuptake Inhibitors (SSRIs) and tricyclic antidepressants. The results indicate that SSRIs, such as escitalopram, consistently demonstrate efficacy in reducing anxiety symptoms compared to placebos. Additionally, tricyclic antidepressants, although less commonly prescribed, have proven effective in specific situations, such as in the treatment of social anxiety disorder. The research emphasizes the importance of personalized treatment, considering factors such as the side effect profile, comorbidities, and individual patient characteristics. This personalized approach emerges as crucial for optimizing clinical outcomes and minimizing potential adverse effects. |
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Brazilian Journal of Implantology and Health Sciences |
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Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action.Antidepressivos na Ansiedade: Uma Abordagem Abrangente da Eficácia e Mecanismos de Ação.AntidepressivosAnsiedadeTratamentoMedicamentosAntidepressantsanxietyThis paper conducts a comprehensive literature review on the role of antidepressants in the treatment of anxiety. The analysis includes controlled clinical trials and systematic reviews addressing the efficacy of different classes of antidepressants, with a primary focus on Selective Serotonin Reuptake Inhibitors (SSRIs) and tricyclic antidepressants. The results indicate that SSRIs, such as escitalopram, consistently demonstrate efficacy in reducing anxiety symptoms compared to placebos. Additionally, tricyclic antidepressants, although less commonly prescribed, have proven effective in specific situations, such as in the treatment of social anxiety disorder. The research emphasizes the importance of personalized treatment, considering factors such as the side effect profile, comorbidities, and individual patient characteristics. This personalized approach emerges as crucial for optimizing clinical outcomes and minimizing potential adverse effects.Este trabalho realiza uma revisão abrangente da literatura sobre o papel dos antidepressivos no tratamento da ansiedade. A análise inclui estudos clínicos controlados e revisões sistemáticas que abordam a eficácia de diferentes classes de antidepressivos, com foco principal nos Inibidores Seletivos da Recaptação de Serotonina (ISRS) e antidepressivos tricíclicos. Os resultados indicam que os ISRS, como o escitalopram, demonstram consistentemente eficácia na redução dos sintomas de ansiedade em comparação com placebos. Além disso, os antidepressivos tricíclicos, apesar de menos prescritos, mostraram-se eficazes em situações específicas, como no tratamento do transtorno de ansiedade social. A pesquisa enfatiza a importância da individualização do tratamento, considerando fatores como o perfil de efeitos colaterais, comorbidades e características individuais do paciente. Essa abordagem personalizada emerge como crucial para otimizar os resultados clínicos e minimizar potenciais efeitos adversos.Specialized Dentistry Group2024-01-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://bjihs.emnuvens.com.br/bjihs/article/view/129110.36557/2674-8169.2024v6n1p1716-1722Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 1 (2024): BJIHS QUALIS B3; 1716-1722Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 1 (2024): BJIHS QUALIS B3; 1716-1722Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 1 (2024): BJIHS QUALIS B3; 1716-17222674-8169reponame:Brazilian Journal of Implantology and Health Sciencesinstname:Grupo de Odontologia Especializada (GOE)instacron:GOEporhttps://bjihs.emnuvens.com.br/bjihs/article/view/1291/1494Copyright (c) 2024 José Lucas Moura Vasconcelos, Amabile Manfroi , Antônio Carlos Gargioni Filho , Carla Maria Zanelli Pinaty , Danyllo Fagundes Evangelista , Gilmara Gabrielli Gregory , Giordana Gregório Fritsch , Iara de Campos Brunetta, Izadora Fernanda Barros , Kauara Marcelino Gonçalves , Lara de Campos Brunetta , Leonardo Gomes Silva Rosa , Marcos Vinicius Maldonado de Barros Lacerda, Maria Clara de Alencar Figueiredo, Maria Eduarda Coelho de Menezes , Maria Eduarda Fornari Cenci , Maria Eduarda Miranda Sansão, Miguel Gramulha Filho , Nathalia Sofia Mayer Ceron , Thais Torres Galindo Dantas , Thiago Rodrigues de Oliveirahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Vasconcelos, José Lucas MouraManfroi , AmabileFilho , Antônio Carlos GargioniPinaty , Carla Maria ZanelliEvangelista , Danyllo Fagundes Gregory , Gilmara GabrielliFritsch , Giordana GregórioBrunetta, Iara de CamposBarros , Izadora FernandaGonçalves , Kauara MarcelinoBrunetta , Lara de CamposRosa , Leonardo Gomes SilvaLacerda, Marcos Vinicius Maldonado de BarrosFigueiredo, Maria Clara de Alencar Menezes , Maria Eduarda Coelho deCenci , Maria Eduarda FornariSansão, Maria Eduarda MirandaFilho , Miguel GramulhaCeron , Nathalia Sofia Mayer Dantas , Thais Torres GalindoOliveira, Thiago Rodrigues de2024-01-24T12:43:00Zoai:ojs.bjihs.emnuvens.com.br:article/1291Revistahttps://bjihs.emnuvens.com.br/bjihsONGhttps://bjihs.emnuvens.com.br/bjihs/oaijournal.bjihs@periodicosbrasil.com.br2674-81692674-8169opendoar:2024-01-24T12:43Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE)false |
dc.title.none.fl_str_mv |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. Antidepressivos na Ansiedade: Uma Abordagem Abrangente da Eficácia e Mecanismos de Ação. |
title |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. |
spellingShingle |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. Vasconcelos, José Lucas Moura Antidepressivos Ansiedade Tratamento Medicamentos Antidepressants anxiety |
title_short |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. |
title_full |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. |
title_fullStr |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. |
title_full_unstemmed |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. |
title_sort |
Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action. |
author |
Vasconcelos, José Lucas Moura |
author_facet |
Vasconcelos, José Lucas Moura Manfroi , Amabile Filho , Antônio Carlos Gargioni Pinaty , Carla Maria Zanelli Evangelista , Danyllo Fagundes Gregory , Gilmara Gabrielli Fritsch , Giordana Gregório Brunetta, Iara de Campos Barros , Izadora Fernanda Gonçalves , Kauara Marcelino Brunetta , Lara de Campos Rosa , Leonardo Gomes Silva Lacerda, Marcos Vinicius Maldonado de Barros Figueiredo, Maria Clara de Alencar Menezes , Maria Eduarda Coelho de Cenci , Maria Eduarda Fornari Sansão, Maria Eduarda Miranda Filho , Miguel Gramulha Ceron , Nathalia Sofia Mayer Dantas , Thais Torres Galindo Oliveira, Thiago Rodrigues de |
author_role |
author |
author2 |
Manfroi , Amabile Filho , Antônio Carlos Gargioni Pinaty , Carla Maria Zanelli Evangelista , Danyllo Fagundes Gregory , Gilmara Gabrielli Fritsch , Giordana Gregório Brunetta, Iara de Campos Barros , Izadora Fernanda Gonçalves , Kauara Marcelino Brunetta , Lara de Campos Rosa , Leonardo Gomes Silva Lacerda, Marcos Vinicius Maldonado de Barros Figueiredo, Maria Clara de Alencar Menezes , Maria Eduarda Coelho de Cenci , Maria Eduarda Fornari Sansão, Maria Eduarda Miranda Filho , Miguel Gramulha Ceron , Nathalia Sofia Mayer Dantas , Thais Torres Galindo Oliveira, Thiago Rodrigues de |
author2_role |
author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Vasconcelos, José Lucas Moura Manfroi , Amabile Filho , Antônio Carlos Gargioni Pinaty , Carla Maria Zanelli Evangelista , Danyllo Fagundes Gregory , Gilmara Gabrielli Fritsch , Giordana Gregório Brunetta, Iara de Campos Barros , Izadora Fernanda Gonçalves , Kauara Marcelino Brunetta , Lara de Campos Rosa , Leonardo Gomes Silva Lacerda, Marcos Vinicius Maldonado de Barros Figueiredo, Maria Clara de Alencar Menezes , Maria Eduarda Coelho de Cenci , Maria Eduarda Fornari Sansão, Maria Eduarda Miranda Filho , Miguel Gramulha Ceron , Nathalia Sofia Mayer Dantas , Thais Torres Galindo Oliveira, Thiago Rodrigues de |
dc.subject.por.fl_str_mv |
Antidepressivos Ansiedade Tratamento Medicamentos Antidepressants anxiety |
topic |
Antidepressivos Ansiedade Tratamento Medicamentos Antidepressants anxiety |
description |
This paper conducts a comprehensive literature review on the role of antidepressants in the treatment of anxiety. The analysis includes controlled clinical trials and systematic reviews addressing the efficacy of different classes of antidepressants, with a primary focus on Selective Serotonin Reuptake Inhibitors (SSRIs) and tricyclic antidepressants. The results indicate that SSRIs, such as escitalopram, consistently demonstrate efficacy in reducing anxiety symptoms compared to placebos. Additionally, tricyclic antidepressants, although less commonly prescribed, have proven effective in specific situations, such as in the treatment of social anxiety disorder. The research emphasizes the importance of personalized treatment, considering factors such as the side effect profile, comorbidities, and individual patient characteristics. This personalized approach emerges as crucial for optimizing clinical outcomes and minimizing potential adverse effects. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-01-23 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/1291 10.36557/2674-8169.2024v6n1p1716-1722 |
url |
https://bjihs.emnuvens.com.br/bjihs/article/view/1291 |
identifier_str_mv |
10.36557/2674-8169.2024v6n1p1716-1722 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/1291/1494 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Specialized Dentistry Group |
publisher.none.fl_str_mv |
Specialized Dentistry Group |
dc.source.none.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 1 (2024): BJIHS QUALIS B3; 1716-1722 Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 1 (2024): BJIHS QUALIS B3; 1716-1722 Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 1 (2024): BJIHS QUALIS B3; 1716-1722 2674-8169 reponame:Brazilian Journal of Implantology and Health Sciences instname:Grupo de Odontologia Especializada (GOE) instacron:GOE |
instname_str |
Grupo de Odontologia Especializada (GOE) |
instacron_str |
GOE |
institution |
GOE |
reponame_str |
Brazilian Journal of Implantology and Health Sciences |
collection |
Brazilian Journal of Implantology and Health Sciences |
repository.name.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE) |
repository.mail.fl_str_mv |
journal.bjihs@periodicosbrasil.com.br |
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1796798443676499968 |