Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications

Detalhes bibliográficos
Autor(a) principal: Silva Bueno , Larissa Fernanda
Data de Publicação: 2024
Outros Autores: Soares Aragão, José Henrique, Tobias da Silva , Ana Beatriz, Dias do Nascimento, Brenda, Jahel Meireles, Danilo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Implantology and Health Sciences
Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1649
Resumo: In this analysis, several therapeutic strategies for the treatment of Irritable Bowel Syndrome (IBS) are examined, with a focus on microbiota modulation and the use of specific medications. Initially, we highlight the effectiveness of recently developed pharmacological interventions, emphasizing their ability to control IBS symptoms and improve patients' quality of life. These emerging therapies not only aim to alleviate symptoms but also seek to address the underlying causes of the condition, taking into account the complex interaction between intestinal microbiota and environmental factors. In addition to pharmacological interventions, innovative approaches such as modulation of intestinal microbiota are being explored to restore the balance of affected gut flora in IBS. These strategies include the use of probiotics, prebiotics, and symbiotics, which have been shown to promote gut health and reduce IBS symptoms in some patients. Ongoing research in this field is crucial for identifying the most effective microbial strains and better understanding how they can benefit individuals with IBS. Furthermore, it is important to highlight the role of specific medications in the treatment of IBS, including antispasmodic agents, intestinal motility modulators, and visceral pain regulators. These medications aim to alleviate gastrointestinal symptoms such as abdominal pain, bloating, and changes in bowel movements, providing relief to patients affected by IBS. In summary, the approach to treating Irritable Bowel Syndrome is increasingly focused on microbiota modulation and the use of specific medications. The integration of these therapeutic strategies can offer a more comprehensive and personalized approach to IBS management, significantly improving patients' quality of life. However, further research is needed to fully understand the underlying mechanisms and optimize the use of these therapeutic interventions in clinical practice.  
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spelling Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific MedicationsAbordagem no Tratamento da Síndrome do Intestino Irritável: Modulação da Microbiota e Medicamentos EspecíficosSíndrome do Intestino Irritável; Modulação da Microbiota; Medicamentos Específicos.rritable Bowel Syndrome; Microbiota Modulation; Specific Medications. In this analysis, several therapeutic strategies for the treatment of Irritable Bowel Syndrome (IBS) are examined, with a focus on microbiota modulation and the use of specific medications. Initially, we highlight the effectiveness of recently developed pharmacological interventions, emphasizing their ability to control IBS symptoms and improve patients' quality of life. These emerging therapies not only aim to alleviate symptoms but also seek to address the underlying causes of the condition, taking into account the complex interaction between intestinal microbiota and environmental factors. In addition to pharmacological interventions, innovative approaches such as modulation of intestinal microbiota are being explored to restore the balance of affected gut flora in IBS. These strategies include the use of probiotics, prebiotics, and symbiotics, which have been shown to promote gut health and reduce IBS symptoms in some patients. Ongoing research in this field is crucial for identifying the most effective microbial strains and better understanding how they can benefit individuals with IBS. Furthermore, it is important to highlight the role of specific medications in the treatment of IBS, including antispasmodic agents, intestinal motility modulators, and visceral pain regulators. These medications aim to alleviate gastrointestinal symptoms such as abdominal pain, bloating, and changes in bowel movements, providing relief to patients affected by IBS. In summary, the approach to treating Irritable Bowel Syndrome is increasingly focused on microbiota modulation and the use of specific medications. The integration of these therapeutic strategies can offer a more comprehensive and personalized approach to IBS management, significantly improving patients' quality of life. However, further research is needed to fully understand the underlying mechanisms and optimize the use of these therapeutic interventions in clinical practice.  Nesta análise, são examinadas várias estratégias terapêuticas para o tratamento da Síndrome do Intestino Irritável (SII), com foco na modulação da microbiota e no uso de medicamentos específicos. Inicialmente, destacamos a eficácia das intervenções farmacológicas recentes desenvolvidas, enfatizando sua capacidade de controlar os sintomas da SII e melhorar a qualidade de vida dos pacientes. Essas terapias emergentes não se limitam apenas ao alívio dos sintomas, mas também buscam abordar as causas subjacentes da condição, levando em consideração a complexa interação entre a microbiota intestinal e fatores ambientais. Além das intervenções farmacológicas, estão sendo exploradas abordagens inovadoras, como a modulação da microbiota intestinal, que visa restaurar o equilíbrio da flora intestinal afetada na SII. Essas estratégias incluem o uso de probióticos, prebióticos e simbióticos, que demonstraram promover a saúde intestinal e reduzir os sintomas da SII em alguns pacientes. A pesquisa contínua nesse campo é crucial para identificar as cepas microbianas mais eficazes e entender melhor como elas podem beneficiar os indivíduos com SII. Além disso, é importante destacar o papel dos medicamentos específicos no tratamento da SII, incluindo agentes antiespasmódicos, moduladores da motilidade intestinal e agentes reguladores da dor visceral. Esses medicamentos visam aliviar os sintomas gastrointestinais, como dor abdominal, distensão e alterações no trânsito intestinal, proporcionando alívio aos pacientes afetados pela SII. Em resumo, a abordagem no tratamento da Síndrome do Intestino Irritável está cada vez mais focada na modulação da microbiota e no uso de medicamentos específicos. A integração dessas estratégias terapêuticas pode oferecer uma abordagem mais abrangente e personalizada para o manejo da SII, melhorando significativamente a qualidade de vida dos pacientes. No entanto, são necessárias mais pesquisas para entender completamente os mecanismos subjacentes e otimizar o uso dessas intervenções terapêuticas na prática clínica.Specialized Dentistry Group2024-03-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://bjihs.emnuvens.com.br/bjihs/article/view/164910.36557/2674-8169.2024v6n3p1041-1054Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 3 (2024): BJIHS QUALIS B3; 1041-1054Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 3 (2024): BJIHS QUALIS B3; 1041-1054Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 3 (2024): BJIHS QUALIS B3; 1041-10542674-8169reponame:Brazilian Journal of Implantology and Health Sciencesinstname:Grupo de Odontologia Especializada (GOE)instacron:GOEporhttps://bjihs.emnuvens.com.br/bjihs/article/view/1649/1848Copyright (c) 2024 Larissa Fernanda Silva Bueno , José Henrique Soares Aragão, Ana Beatriz Tobias da Silva , Brenda Dias do Nascimento, Danilo Jahel Meireleshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva Bueno , Larissa FernandaSoares Aragão, José HenriqueTobias da Silva , Ana Beatriz Dias do Nascimento, Brenda Jahel Meireles, Danilo2024-03-12T21:22:26Zoai:ojs.bjihs.emnuvens.com.br:article/1649Revistahttps://bjihs.emnuvens.com.br/bjihsONGhttps://bjihs.emnuvens.com.br/bjihs/oaijournal.bjihs@periodicosbrasil.com.br2674-81692674-8169opendoar:2024-03-12T21:22:26Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE)false
dc.title.none.fl_str_mv Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
Abordagem no Tratamento da Síndrome do Intestino Irritável: Modulação da Microbiota e Medicamentos Específicos
title Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
spellingShingle Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
Silva Bueno , Larissa Fernanda
Síndrome do Intestino Irritável; Modulação da Microbiota; Medicamentos Específicos.
rritable Bowel Syndrome; Microbiota Modulation; Specific Medications.
title_short Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
title_full Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
title_fullStr Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
title_full_unstemmed Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
title_sort Approach to the Treatment of Irritable Bowel Syndrome: Modulation of the Microbiota and Specific Medications
author Silva Bueno , Larissa Fernanda
author_facet Silva Bueno , Larissa Fernanda
Soares Aragão, José Henrique
Tobias da Silva , Ana Beatriz
Dias do Nascimento, Brenda
Jahel Meireles, Danilo
author_role author
author2 Soares Aragão, José Henrique
Tobias da Silva , Ana Beatriz
Dias do Nascimento, Brenda
Jahel Meireles, Danilo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva Bueno , Larissa Fernanda
Soares Aragão, José Henrique
Tobias da Silva , Ana Beatriz
Dias do Nascimento, Brenda
Jahel Meireles, Danilo
dc.subject.por.fl_str_mv Síndrome do Intestino Irritável; Modulação da Microbiota; Medicamentos Específicos.
rritable Bowel Syndrome; Microbiota Modulation; Specific Medications.
topic Síndrome do Intestino Irritável; Modulação da Microbiota; Medicamentos Específicos.
rritable Bowel Syndrome; Microbiota Modulation; Specific Medications.
description In this analysis, several therapeutic strategies for the treatment of Irritable Bowel Syndrome (IBS) are examined, with a focus on microbiota modulation and the use of specific medications. Initially, we highlight the effectiveness of recently developed pharmacological interventions, emphasizing their ability to control IBS symptoms and improve patients' quality of life. These emerging therapies not only aim to alleviate symptoms but also seek to address the underlying causes of the condition, taking into account the complex interaction between intestinal microbiota and environmental factors. In addition to pharmacological interventions, innovative approaches such as modulation of intestinal microbiota are being explored to restore the balance of affected gut flora in IBS. These strategies include the use of probiotics, prebiotics, and symbiotics, which have been shown to promote gut health and reduce IBS symptoms in some patients. Ongoing research in this field is crucial for identifying the most effective microbial strains and better understanding how they can benefit individuals with IBS. Furthermore, it is important to highlight the role of specific medications in the treatment of IBS, including antispasmodic agents, intestinal motility modulators, and visceral pain regulators. These medications aim to alleviate gastrointestinal symptoms such as abdominal pain, bloating, and changes in bowel movements, providing relief to patients affected by IBS. In summary, the approach to treating Irritable Bowel Syndrome is increasingly focused on microbiota modulation and the use of specific medications. The integration of these therapeutic strategies can offer a more comprehensive and personalized approach to IBS management, significantly improving patients' quality of life. However, further research is needed to fully understand the underlying mechanisms and optimize the use of these therapeutic interventions in clinical practice.  
publishDate 2024
dc.date.none.fl_str_mv 2024-03-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://bjihs.emnuvens.com.br/bjihs/article/view/1649
10.36557/2674-8169.2024v6n3p1041-1054
url https://bjihs.emnuvens.com.br/bjihs/article/view/1649
identifier_str_mv 10.36557/2674-8169.2024v6n3p1041-1054
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://bjihs.emnuvens.com.br/bjihs/article/view/1649/1848
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Specialized Dentistry Group
publisher.none.fl_str_mv Specialized Dentistry Group
dc.source.none.fl_str_mv Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 3 (2024): BJIHS QUALIS B3; 1041-1054
Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 3 (2024): BJIHS QUALIS B3; 1041-1054
Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 3 (2024): BJIHS QUALIS B3; 1041-1054
2674-8169
reponame:Brazilian Journal of Implantology and Health Sciences
instname:Grupo de Odontologia Especializada (GOE)
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instname_str Grupo de Odontologia Especializada (GOE)
instacron_str GOE
institution GOE
reponame_str Brazilian Journal of Implantology and Health Sciences
collection Brazilian Journal of Implantology and Health Sciences
repository.name.fl_str_mv Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE)
repository.mail.fl_str_mv journal.bjihs@periodicosbrasil.com.br
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