A ADSORÇÃO DE PROTEINAS NO ESPAÇO DE OSTEOCONDUÇÃO

• Autor(a) principal: Rosa de Almeida, Ana Carolina
• Data de Publicação: 2022
• Outros Autores: Serqueira da Silva, Nicole, Nascimento, Marvin, Martins de Souza, Bruno, Tany Posh, Aline
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/214
• topic: osseointegração; implantes dentários; implantes de titânio; biomateriais; adsorção de proteinas; osseointegration; dental implants; titanium implants; biomaterials; protein adsorption

Introduction: Osseointegration is a process that allows the interaction of titanium implants with bone tissue. This interface is permeated by a protein anchoring so that the biomaterial is not in direct contact with the periosteum. Objective: This literature review aims to present the process of protein adsorption in osseointegrated implants, highlighting the main proteins that participate in this process. Methodology: The search was conducted on the PubMed, SciELO and Google Academic platforms with articles published between 2008 and 2022 in Portuguese and English. Results: Soon after implant installation, a provisional fibrin matrix is formed (angiogenesis process) that precedes osseointegration. Afterwards, in the osteoconduction space, there is an interaction between the titanium implant surface and proteins from the cell membrane. Thus, this protein interaction will support the peri-implant ligament. However, different factors such as implant surface properties and protein properties may influence this adsorption process. Conclusion: In this sense, it can be assumed that protein adsorption is an indispensable mechanism for successful osseointegration in titanium and titanium alloy implants.