Cutting-Edge Therapeutic Advances for Hematologic Cancers: Leukemia, Lymphoma, and Myeloma.

• Autor(a) principal: Severino , Victor Vilela Carvalho
• Data de Publicação: 2023
• Outros Autores: Reis , Gustavo Novelino, Silva , Ana Paula Oliveira, Passos , Arthur Mendes Porto, Mendonça , Ariany Parreira de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/573
• topic: Cânceres hematológicos; terapias-alvo; imunoterapia; avanços terapêuticos; terapia CAR-T

This review article highlights cutting-edge therapeutic advancements in hematologic cancers such as leukemia, lymphoma, and myeloma, which are revolutionizing the landscape of treating these diseases. Targeted therapies, immunotherapies, and CAR-T therapy have emerged as fundamental pillars in combating hematologic cancer, offering remarkable outcomes like profound and enduring responses. The customization of treatment tailored to individual patient and disease characteristics has proven crucial in this context, though significant challenges persist, including therapeutic resistance and global accessibility. Nonetheless, the future of hematologic oncology holds promise, with ongoing research directed towards enhancing patients' quality of life and survival prospects, instilling hope and fostering continuous progress in the field of oncologic hematology. These therapeutic innovations signify a milestone in the battle against hematologic cancers, yielding previously unimaginable results. Targeted therapies aimed at specific mutations, immunotherapy bolstering the patient's immune system, and CAR-T therapy employing modified immune cells to target cancerous cells are demonstrating remarkable efficacy, offering hope for both patients and clinicians. Nevertheless, challenges remain, necessitating the management of therapeutic resistance that may arise over time and ensuring global access to these advanced therapies. As research continues to advance, the horizon of hematologic oncology promises ongoing enhancements in patients' quality of life and survival prospects, establishing a scenario where hematologic cancer can be effectively treated with renewed hope.