THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
Autor(a) principal: | |
---|---|
Data de Publicação: | 2024 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Implantology and Health Sciences |
Texto Completo: | https://bjihs.emnuvens.com.br/bjihs/article/view/1480 |
Resumo: | The therapeutic approach to AD is constantly evolving, ranging from pharmacological advances to innovative strategies aimed at improving neuroplasticity. This diversity of therapeutic options reflects an ongoing effort to offer more effective and comprehensive treatments for those affected by AD, highlighting the importance of continuously developing therapeutic strategies in this challenging scenario. The aim of this study was to identify therapeutic approaches aimed at preventing the progression of Alzheimer's disease. A systematic literature review was carried out using the Scielo, Lilacs and Medline databases. In conclusion, therapeutic approaches to Alzheimer's disease are diverse and constantly evolving. Although there have been promising advances, especially in pharmacological strategies such as the use of monoclonal antibodies, gene therapy and nanotechnology, challenges remain, including variation in the effectiveness of specific treatments and the ongoing need to assess potential long-term adverse effects. |
id |
GOE-1_f0865d128e5b1d4ba21a29a0b6f195a1 |
---|---|
oai_identifier_str |
oai:ojs.bjihs.emnuvens.com.br:article/1480 |
network_acronym_str |
GOE-1 |
network_name_str |
Brazilian Journal of Implantology and Health Sciences |
repository_id_str |
|
spelling |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSISABORDAGENS TERAPÊUTICAS NA PREVENÇÃO DA PROGRESSÃO DA DOENÇA DE ALZHEIMER: UMA REVISÃO SISTEMÁTICA E META-ANÁLISEAlzheimer. Abordagens terapêuticas. Prevenção.Alzheimer's. Therapeutic approaches. Prevention.The therapeutic approach to AD is constantly evolving, ranging from pharmacological advances to innovative strategies aimed at improving neuroplasticity. This diversity of therapeutic options reflects an ongoing effort to offer more effective and comprehensive treatments for those affected by AD, highlighting the importance of continuously developing therapeutic strategies in this challenging scenario. The aim of this study was to identify therapeutic approaches aimed at preventing the progression of Alzheimer's disease. A systematic literature review was carried out using the Scielo, Lilacs and Medline databases. In conclusion, therapeutic approaches to Alzheimer's disease are diverse and constantly evolving. Although there have been promising advances, especially in pharmacological strategies such as the use of monoclonal antibodies, gene therapy and nanotechnology, challenges remain, including variation in the effectiveness of specific treatments and the ongoing need to assess potential long-term adverse effects.A abordagem terapêutica na DA está em constante evolução, abrangendo desde avanços farmacológicos até estratégias inovadoras que visam aprimorar a neuroplasticidade. Essa diversidade de opções terapêuticas reflete um esforço contínuo para oferecer tratamentos mais eficazes e abrangentes para os afetados pela DA, destacando a importância do desenvolvimento contínuo de estratégias terapêuticas nesse cenário desafiador. Trata-se de um estudo cujo objetivo foi identificar abordagens terapêuticas destinadas à prevenção da progressão da doença de Alzheimer. Nesse sentido, foi desenvolvida uma revisão sistemática da literatura, utilizando as bases de dados Scielo, Lilacs e Medline. Como conclusão, tem-se que as abordagens terapêuticas para a doença de Alzheimer são diversas e em constante evolução. Embora haja avanços promissores, especialmente em estratégias farmacológicas como o uso de anticorpos monoclonais, terapia genética e nanotecnologia, desafios persistem, incluindo a variação na eficácia de tratamentos específicos e a necessidade contínua de avaliação de potenciais efeitos adversos a longo prazo.Specialized Dentistry Group2024-02-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://bjihs.emnuvens.com.br/bjihs/article/view/148010.36557/2674-8169.2024v6n2p1211-1227Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 2 (2024): BJIHS QUALIS B3; 1211-1227Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 2 (2024): BJIHS QUALIS B3; 1211-1227Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 2 (2024): BJIHS QUALIS B3; 1211-12272674-8169reponame:Brazilian Journal of Implantology and Health Sciencesinstname:Grupo de Odontologia Especializada (GOE)instacron:GOEporhttps://bjihs.emnuvens.com.br/bjihs/article/view/1480/1889Copyright (c) 2024 Gabriela Cruz de Oliveira, Nathalia Sbampato Mol Bessa, Lucas Oliveira Dabien Haddad, Cleaide Ataíde Lima Assunção, José Lima Assuncao Júnior, Áurea Amélia Coutinho Nogueira de Albuquerque , Maria Lúcia Brito de Araujo Paysano, Pietro Brandão Gouveia, Juliana Gomes Cruz, Rômulo Basílio Ferro Gomes Cavalcante , Igor Bonifácio Andrade Coímbra , Fiama Jéssica Francieli Cardoso Rapette , Júlia Rodna Gomes Paiva Arcanjo de Moraishttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Gabriela Cruz deBessa, Nathalia Sbampato MolHaddad, Lucas Oliveira DabienAssunção, Cleaide Ataíde LimaAssuncao Júnior, José LimaAlbuquerque , Áurea Amélia Coutinho Nogueira dePaysano, Maria Lúcia Brito de AraujoGouveia, Pietro BrandãoCruz, Juliana GomesCavalcante , Rômulo Basílio Ferro GomesCoímbra , Igor Bonifácio AndradeRapette , Fiama Jéssica Francieli CardosoMorais, Júlia Rodna Gomes Paiva Arcanjo deMartins, Vitoria RorizNeves, Sara Izabel Cargnin HenriqueFerreira , Laís Jaciara Costa RevilRamos, Isabela CostaMiguez, Juliana PinhoCerqueira jr , Vanilson PiresBarbosa , Matheus FonsecaVieira , Izadora CarneiroReis, Davi BaymaPereira, Narjara Samya RodriguesGiácomo, Brenda Santana AraujoFé Filho, Rogério Lopes de Moura2024-03-18T14:02:11Zoai:ojs.bjihs.emnuvens.com.br:article/1480Revistahttps://bjihs.emnuvens.com.br/bjihsONGhttps://bjihs.emnuvens.com.br/bjihs/oaijournal.bjihs@periodicosbrasil.com.br2674-81692674-8169opendoar:2024-03-18T14:02:11Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE)false |
dc.title.none.fl_str_mv |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS ABORDAGENS TERAPÊUTICAS NA PREVENÇÃO DA PROGRESSÃO DA DOENÇA DE ALZHEIMER: UMA REVISÃO SISTEMÁTICA E META-ANÁLISE |
title |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS |
spellingShingle |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS Oliveira, Gabriela Cruz de Alzheimer. Abordagens terapêuticas. Prevenção. Alzheimer's. Therapeutic approaches. Prevention. |
title_short |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS |
title_full |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS |
title_fullStr |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS |
title_full_unstemmed |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS |
title_sort |
THERAPEUTIC APPROACHES IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS |
author |
Oliveira, Gabriela Cruz de |
author_facet |
Oliveira, Gabriela Cruz de Bessa, Nathalia Sbampato Mol Haddad, Lucas Oliveira Dabien Assunção, Cleaide Ataíde Lima Assuncao Júnior, José Lima Albuquerque , Áurea Amélia Coutinho Nogueira de Paysano, Maria Lúcia Brito de Araujo Gouveia, Pietro Brandão Cruz, Juliana Gomes Cavalcante , Rômulo Basílio Ferro Gomes Coímbra , Igor Bonifácio Andrade Rapette , Fiama Jéssica Francieli Cardoso Morais, Júlia Rodna Gomes Paiva Arcanjo de Martins, Vitoria Roriz Neves, Sara Izabel Cargnin Henrique Ferreira , Laís Jaciara Costa Revil Ramos, Isabela Costa Miguez, Juliana Pinho Cerqueira jr , Vanilson Pires Barbosa , Matheus Fonseca Vieira , Izadora Carneiro Reis, Davi Bayma Pereira, Narjara Samya Rodrigues Giácomo, Brenda Santana Araujo Fé Filho, Rogério Lopes de Moura |
author_role |
author |
author2 |
Bessa, Nathalia Sbampato Mol Haddad, Lucas Oliveira Dabien Assunção, Cleaide Ataíde Lima Assuncao Júnior, José Lima Albuquerque , Áurea Amélia Coutinho Nogueira de Paysano, Maria Lúcia Brito de Araujo Gouveia, Pietro Brandão Cruz, Juliana Gomes Cavalcante , Rômulo Basílio Ferro Gomes Coímbra , Igor Bonifácio Andrade Rapette , Fiama Jéssica Francieli Cardoso Morais, Júlia Rodna Gomes Paiva Arcanjo de Martins, Vitoria Roriz Neves, Sara Izabel Cargnin Henrique Ferreira , Laís Jaciara Costa Revil Ramos, Isabela Costa Miguez, Juliana Pinho Cerqueira jr , Vanilson Pires Barbosa , Matheus Fonseca Vieira , Izadora Carneiro Reis, Davi Bayma Pereira, Narjara Samya Rodrigues Giácomo, Brenda Santana Araujo Fé Filho, Rogério Lopes de Moura |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Gabriela Cruz de Bessa, Nathalia Sbampato Mol Haddad, Lucas Oliveira Dabien Assunção, Cleaide Ataíde Lima Assuncao Júnior, José Lima Albuquerque , Áurea Amélia Coutinho Nogueira de Paysano, Maria Lúcia Brito de Araujo Gouveia, Pietro Brandão Cruz, Juliana Gomes Cavalcante , Rômulo Basílio Ferro Gomes Coímbra , Igor Bonifácio Andrade Rapette , Fiama Jéssica Francieli Cardoso Morais, Júlia Rodna Gomes Paiva Arcanjo de Martins, Vitoria Roriz Neves, Sara Izabel Cargnin Henrique Ferreira , Laís Jaciara Costa Revil Ramos, Isabela Costa Miguez, Juliana Pinho Cerqueira jr , Vanilson Pires Barbosa , Matheus Fonseca Vieira , Izadora Carneiro Reis, Davi Bayma Pereira, Narjara Samya Rodrigues Giácomo, Brenda Santana Araujo Fé Filho, Rogério Lopes de Moura |
dc.subject.por.fl_str_mv |
Alzheimer. Abordagens terapêuticas. Prevenção. Alzheimer's. Therapeutic approaches. Prevention. |
topic |
Alzheimer. Abordagens terapêuticas. Prevenção. Alzheimer's. Therapeutic approaches. Prevention. |
description |
The therapeutic approach to AD is constantly evolving, ranging from pharmacological advances to innovative strategies aimed at improving neuroplasticity. This diversity of therapeutic options reflects an ongoing effort to offer more effective and comprehensive treatments for those affected by AD, highlighting the importance of continuously developing therapeutic strategies in this challenging scenario. The aim of this study was to identify therapeutic approaches aimed at preventing the progression of Alzheimer's disease. A systematic literature review was carried out using the Scielo, Lilacs and Medline databases. In conclusion, therapeutic approaches to Alzheimer's disease are diverse and constantly evolving. Although there have been promising advances, especially in pharmacological strategies such as the use of monoclonal antibodies, gene therapy and nanotechnology, challenges remain, including variation in the effectiveness of specific treatments and the ongoing need to assess potential long-term adverse effects. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-02-13 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/1480 10.36557/2674-8169.2024v6n2p1211-1227 |
url |
https://bjihs.emnuvens.com.br/bjihs/article/view/1480 |
identifier_str_mv |
10.36557/2674-8169.2024v6n2p1211-1227 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/1480/1889 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Specialized Dentistry Group |
publisher.none.fl_str_mv |
Specialized Dentistry Group |
dc.source.none.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences ; Vol. 6 No. 2 (2024): BJIHS QUALIS B3; 1211-1227 Brazilian Journal of Implantology and Health Sciences ; Vol. 6 Núm. 2 (2024): BJIHS QUALIS B3; 1211-1227 Brazilian Journal of Implantology and Health Sciences ; v. 6 n. 2 (2024): BJIHS QUALIS B3; 1211-1227 2674-8169 reponame:Brazilian Journal of Implantology and Health Sciences instname:Grupo de Odontologia Especializada (GOE) instacron:GOE |
instname_str |
Grupo de Odontologia Especializada (GOE) |
instacron_str |
GOE |
institution |
GOE |
reponame_str |
Brazilian Journal of Implantology and Health Sciences |
collection |
Brazilian Journal of Implantology and Health Sciences |
repository.name.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE) |
repository.mail.fl_str_mv |
journal.bjihs@periodicosbrasil.com.br |
_version_ |
1796798445031260160 |