The pathophysiology of covid-19 resulting in acute kidney injury

Detalhes bibliográficos
Autor(a) principal: Santos, Beatris Pinheiro dos
Data de Publicação: 2023
Outros Autores: Manteli, Gabriela Mendes da Costa, Nunes, Natália Abou Hala
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Educação e Saúde
Texto Completo: https://www.gvaa.com.br/revista/index.php/REBES/article/view/9534
Resumo: During 2019, the World Health Organization (WHO) declared Covid-19 a pandemic disease, in other words, alarming for all regions of the globe. As a consequence of infection with the SARS-CoV-2 virus, several systemic effects were observed, but mainly kidney damage in patients who presented severe conditions. The objective of this literature review is to know the pathophysiology of Covid-19 resulting in Acute Kidney Injury (AKI), in order to seek several practical studies in english and portuguese that answer to this objective. Thus, it is notable that the relationship of this pathology with AKI includes aggression from the angiotensin-converting enzyme 2 (ACE2) present in the kidneys, that is, directly affecting the organ and the effects of the cytokine cascade in the body resulting, directly or indirect, on renal involvement and the clinical symptoms of the sick patient. Finally, the injury of this organ is performed from the inflammatory response and by interference with the enzyme present at the site.
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spelling The pathophysiology of covid-19 resulting in acute kidney injuryA fisiopatologia da covid-19 resultando na lesão renal agudaRenal insufficiencyacute kidney injurykidney diseasesCOVID-19renin-angiotensin systemInsuficiência renalinjúria renal agudanefropatiasCOVID-19sistema renina-angiotensinaDuring 2019, the World Health Organization (WHO) declared Covid-19 a pandemic disease, in other words, alarming for all regions of the globe. As a consequence of infection with the SARS-CoV-2 virus, several systemic effects were observed, but mainly kidney damage in patients who presented severe conditions. The objective of this literature review is to know the pathophysiology of Covid-19 resulting in Acute Kidney Injury (AKI), in order to seek several practical studies in english and portuguese that answer to this objective. Thus, it is notable that the relationship of this pathology with AKI includes aggression from the angiotensin-converting enzyme 2 (ACE2) present in the kidneys, that is, directly affecting the organ and the effects of the cytokine cascade in the body resulting, directly or indirect, on renal involvement and the clinical symptoms of the sick patient. Finally, the injury of this organ is performed from the inflammatory response and by interference with the enzyme present at the site.Durante o ano de 2019, a Organização Mundial da Saúde (OMS) decretou a Covid-19 como uma doença pandêmica, isto é, alarmante para todas as regiões do globo. Como consequências da infecção pelo vírus SARS-CoV-2, foram observados diversos efeitos sistêmicos, mas, principalmente, a lesão renal nos pacientes que apresentaram quadros graves. O objetivo desta revisão de literatura é conhecer a fisiopatologia da Covid-19 resultando na Lesão Renal Aguda (LRA), de forma a buscar diversos estudos práticos nas línguas inglesa e portuguesa que respondem a esse objetivo. Dessa forma, é notável que as relações dessa patologia com LRA incluem a agressão a partir da enzima de conversão de angiotensina II presente nos rins, ou seja, afetando diretamente o órgão e os efeitos da cascata de citocinas no organismo resultando, de forma direta ou indireta, no acometimento renal e os sintomas clínicos do paciente doente. Por fim, a lesão deste órgão é realizada a partir da resposta inflamatória e por interferência na enzima presente no local.GRUPO VERDE DE AGROECOLOGIA E ABELHAS2023-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.gvaa.com.br/revista/index.php/REBES/article/view/953410.18378/rebes.v13i2.9534Revista Brasileira de Educação e Saúde; Vol. 13 No. 2 (2023); 171-176Revista Brasileira de Educação e Saúde; Vol. 13 Núm. 2 (2023); 171-176Revista Brasileira de Educação e Saúde; v. 13 n. 2 (2023); 171-1762358-2391reponame:Revista Brasileira de Educação e Saúdeinstname:Grupo Verde de Agroecologia e Abelhas (GVAA)instacron:GVAAporhttps://www.gvaa.com.br/revista/index.php/REBES/article/view/9534/11673Copyright (c) 2023 Beatris Pinheiro dos Santos, Gabriela Mendes da Costa Manteli, Natália Abou Hala Nuneshttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Santos, Beatris Pinheiro dosManteli, Gabriela Mendes da Costa Nunes, Natália Abou Hala2023-07-24T03:19:20Zoai:ojs.gvaa.com.br:article/9534Revistahttps://www.gvaa.com.br/revista/index.php/REBESPRIhttp://www.gvaa.com.br/revista/index.php/REBES/oaimilenanunes@fiponline.edu.br||patriciomaracaja@gmail.com2358-23912358-2391opendoar:2023-07-24T03:19:20Revista Brasileira de Educação e Saúde - Grupo Verde de Agroecologia e Abelhas (GVAA)false
dc.title.none.fl_str_mv The pathophysiology of covid-19 resulting in acute kidney injury
A fisiopatologia da covid-19 resultando na lesão renal aguda
title The pathophysiology of covid-19 resulting in acute kidney injury
spellingShingle The pathophysiology of covid-19 resulting in acute kidney injury
Santos, Beatris Pinheiro dos
Renal insufficiency
acute kidney injury
kidney diseases
COVID-19
renin-angiotensin system
Insuficiência renal
injúria renal aguda
nefropatias
COVID-19
sistema renina-angiotensina
title_short The pathophysiology of covid-19 resulting in acute kidney injury
title_full The pathophysiology of covid-19 resulting in acute kidney injury
title_fullStr The pathophysiology of covid-19 resulting in acute kidney injury
title_full_unstemmed The pathophysiology of covid-19 resulting in acute kidney injury
title_sort The pathophysiology of covid-19 resulting in acute kidney injury
author Santos, Beatris Pinheiro dos
author_facet Santos, Beatris Pinheiro dos
Manteli, Gabriela Mendes da Costa
Nunes, Natália Abou Hala
author_role author
author2 Manteli, Gabriela Mendes da Costa
Nunes, Natália Abou Hala
author2_role author
author
dc.contributor.author.fl_str_mv Santos, Beatris Pinheiro dos
Manteli, Gabriela Mendes da Costa
Nunes, Natália Abou Hala
dc.subject.por.fl_str_mv Renal insufficiency
acute kidney injury
kidney diseases
COVID-19
renin-angiotensin system
Insuficiência renal
injúria renal aguda
nefropatias
COVID-19
sistema renina-angiotensina
topic Renal insufficiency
acute kidney injury
kidney diseases
COVID-19
renin-angiotensin system
Insuficiência renal
injúria renal aguda
nefropatias
COVID-19
sistema renina-angiotensina
description During 2019, the World Health Organization (WHO) declared Covid-19 a pandemic disease, in other words, alarming for all regions of the globe. As a consequence of infection with the SARS-CoV-2 virus, several systemic effects were observed, but mainly kidney damage in patients who presented severe conditions. The objective of this literature review is to know the pathophysiology of Covid-19 resulting in Acute Kidney Injury (AKI), in order to seek several practical studies in english and portuguese that answer to this objective. Thus, it is notable that the relationship of this pathology with AKI includes aggression from the angiotensin-converting enzyme 2 (ACE2) present in the kidneys, that is, directly affecting the organ and the effects of the cytokine cascade in the body resulting, directly or indirect, on renal involvement and the clinical symptoms of the sick patient. Finally, the injury of this organ is performed from the inflammatory response and by interference with the enzyme present at the site.
publishDate 2023
dc.date.none.fl_str_mv 2023-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.gvaa.com.br/revista/index.php/REBES/article/view/9534
10.18378/rebes.v13i2.9534
url https://www.gvaa.com.br/revista/index.php/REBES/article/view/9534
identifier_str_mv 10.18378/rebes.v13i2.9534
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.gvaa.com.br/revista/index.php/REBES/article/view/9534/11673
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv GRUPO VERDE DE AGROECOLOGIA E ABELHAS
publisher.none.fl_str_mv GRUPO VERDE DE AGROECOLOGIA E ABELHAS
dc.source.none.fl_str_mv Revista Brasileira de Educação e Saúde; Vol. 13 No. 2 (2023); 171-176
Revista Brasileira de Educação e Saúde; Vol. 13 Núm. 2 (2023); 171-176
Revista Brasileira de Educação e Saúde; v. 13 n. 2 (2023); 171-176
2358-2391
reponame:Revista Brasileira de Educação e Saúde
instname:Grupo Verde de Agroecologia e Abelhas (GVAA)
instacron:GVAA
instname_str Grupo Verde de Agroecologia e Abelhas (GVAA)
instacron_str GVAA
institution GVAA
reponame_str Revista Brasileira de Educação e Saúde
collection Revista Brasileira de Educação e Saúde
repository.name.fl_str_mv Revista Brasileira de Educação e Saúde - Grupo Verde de Agroecologia e Abelhas (GVAA)
repository.mail.fl_str_mv milenanunes@fiponline.edu.br||patriciomaracaja@gmail.com
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