The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de gastroenterologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000300012 |
Resumo: | CONTEXT: Hepatectomy is the treatment of choice for colorectal liver metastases, and several studies have shown good results, with 5-year survival rates ranging from 40% to 57%. Several clinical and pathological predictive factors for survival after liver resection have been studied. Involvement of the hepatic hilum lymph nodes, the incidence of which varies from 2% to 10%, indicates a poor long-term prognosis. RESULTS: Despite variable results, some authors have reported a not-insignificant improvement in survival rate in liver-metastasis patients with hilar lymph node involvement who undergo combined liver resection and lymphadenectomy. Due to the low rates of morbidity and mortality for liver-resection surgery, several specialized centers perform liver resections combined with lymphadenectomies in selected cases. It should be noted that the therapeutic value of systemic lymphadenectomy is not yet entirely understood, and only controlled studies comparing groups with and without lymphadenectomy can fully resolve the issue. CONCLUSION: In any case, hilar lymph node dissection has been shown to be a useful tool for improving the accuracy of extra hepatic disease staging, regardless of its impact on survival. |
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The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasisNeoplasm metastasisLymph node excisionHepatectomyColorectal neoplasmsCONTEXT: Hepatectomy is the treatment of choice for colorectal liver metastases, and several studies have shown good results, with 5-year survival rates ranging from 40% to 57%. Several clinical and pathological predictive factors for survival after liver resection have been studied. Involvement of the hepatic hilum lymph nodes, the incidence of which varies from 2% to 10%, indicates a poor long-term prognosis. RESULTS: Despite variable results, some authors have reported a not-insignificant improvement in survival rate in liver-metastasis patients with hilar lymph node involvement who undergo combined liver resection and lymphadenectomy. Due to the low rates of morbidity and mortality for liver-resection surgery, several specialized centers perform liver resections combined with lymphadenectomies in selected cases. It should be noted that the therapeutic value of systemic lymphadenectomy is not yet entirely understood, and only controlled studies comparing groups with and without lymphadenectomy can fully resolve the issue. CONCLUSION: In any case, hilar lymph node dissection has been shown to be a useful tool for improving the accuracy of extra hepatic disease staging, regardless of its impact on survival.Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE. 2011-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000300012Arquivos de Gastroenterologia v.48 n.3 2011reponame:Arquivos de gastroenterologia (Online)instname:Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologiainstacron:IBEPEGE10.1590/S0004-28032011000300012info:eu-repo/semantics/openAccessViana,Eduardo FreitasHerman,PauloCoelho,Fabrício FerreiraTaka,Thomas AugustoD'Albuquerque,Luiz A. CarneiroCecconello,Ivaneng2011-09-12T00:00:00Zoai:scielo:S0004-28032011000300012Revistahttp://www.scielo.br/aghttps://old.scielo.br/oai/scielo-oai.php||secretariaarqgastr@hospitaligesp.com.br1678-42190004-2803opendoar:2011-09-12T00:00Arquivos de gastroenterologia (Online) - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologiafalse |
dc.title.none.fl_str_mv |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
title |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
spellingShingle |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis Viana,Eduardo Freitas Neoplasm metastasis Lymph node excision Hepatectomy Colorectal neoplasms |
title_short |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
title_full |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
title_fullStr |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
title_full_unstemmed |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
title_sort |
The role of hilar lymphadenectomy in patients subjected to hepatectomy due to colorectal metastasis |
author |
Viana,Eduardo Freitas |
author_facet |
Viana,Eduardo Freitas Herman,Paulo Coelho,Fabrício Ferreira Taka,Thomas Augusto D'Albuquerque,Luiz A. Carneiro Cecconello,Ivan |
author_role |
author |
author2 |
Herman,Paulo Coelho,Fabrício Ferreira Taka,Thomas Augusto D'Albuquerque,Luiz A. Carneiro Cecconello,Ivan |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Viana,Eduardo Freitas Herman,Paulo Coelho,Fabrício Ferreira Taka,Thomas Augusto D'Albuquerque,Luiz A. Carneiro Cecconello,Ivan |
dc.subject.por.fl_str_mv |
Neoplasm metastasis Lymph node excision Hepatectomy Colorectal neoplasms |
topic |
Neoplasm metastasis Lymph node excision Hepatectomy Colorectal neoplasms |
description |
CONTEXT: Hepatectomy is the treatment of choice for colorectal liver metastases, and several studies have shown good results, with 5-year survival rates ranging from 40% to 57%. Several clinical and pathological predictive factors for survival after liver resection have been studied. Involvement of the hepatic hilum lymph nodes, the incidence of which varies from 2% to 10%, indicates a poor long-term prognosis. RESULTS: Despite variable results, some authors have reported a not-insignificant improvement in survival rate in liver-metastasis patients with hilar lymph node involvement who undergo combined liver resection and lymphadenectomy. Due to the low rates of morbidity and mortality for liver-resection surgery, several specialized centers perform liver resections combined with lymphadenectomies in selected cases. It should be noted that the therapeutic value of systemic lymphadenectomy is not yet entirely understood, and only controlled studies comparing groups with and without lymphadenectomy can fully resolve the issue. CONCLUSION: In any case, hilar lymph node dissection has been shown to be a useful tool for improving the accuracy of extra hepatic disease staging, regardless of its impact on survival. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000300012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000300012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-28032011000300012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE. |
publisher.none.fl_str_mv |
Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE. |
dc.source.none.fl_str_mv |
Arquivos de Gastroenterologia v.48 n.3 2011 reponame:Arquivos de gastroenterologia (Online) instname:Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia instacron:IBEPEGE |
instname_str |
Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia |
instacron_str |
IBEPEGE |
institution |
IBEPEGE |
reponame_str |
Arquivos de gastroenterologia (Online) |
collection |
Arquivos de gastroenterologia (Online) |
repository.name.fl_str_mv |
Arquivos de gastroenterologia (Online) - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia |
repository.mail.fl_str_mv |
||secretariaarqgastr@hospitaligesp.com.br |
_version_ |
1754193346156298240 |