Bone marrow hypoplasia: atypical manifestation of hyperthyroidism
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Baiana de Saúde Pública (Online) |
Texto Completo: | https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3554 |
Resumo: | Hematological changes such as anemia or pancytopenia can occur as atypical manifestations of hyperthyroidism. Although most cases of pancytopenia in Graves’ disease are due to the use of antithyroid drugs (thionamides), it can also be associated with untreated hyperthyroidism, thus manifesting as a serious complication. This study aims to report the case of a 39-year-old hyperthyroid female patient who developed pancytopenia during hospitalization. Data were collected by means of the medical record, an interview conducted with the patient, and literature review. The patient was admitted to a hospital in Salvador presenting lower extremity edema that progressively evolved to anasarca within 45 days prior to the interview. She also presented weight loss, paroxysmal nocturnal dyspnea, tachycardia, sweating, chills, and laboratory test results for pancytopenia. The case reported here demonstrates an atypical and rare manifestation of hyperthyroidism that improved after the beginning of the treatment, reaching the euthyroid state. |
id |
IBICT-3_a31206b6e707adec46e43bc8cbe8bbf9 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/3554 |
network_acronym_str |
IBICT-3 |
network_name_str |
Revista Baiana de Saúde Pública (Online) |
repository_id_str |
|
spelling |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidismHipoplasia de la médula ósea: manifestación atípica del hipertiroidismoHipoplasia de medula óssea: manifestação atípica do hipertireoidismoHipertireoidismoPancitopeniaTireotoxicoseHipertireoidismoPancitopeniaTireotoxicoseHyperthyroidismPancytopeniaThyrotoxicosisHematological changes such as anemia or pancytopenia can occur as atypical manifestations of hyperthyroidism. Although most cases of pancytopenia in Graves’ disease are due to the use of antithyroid drugs (thionamides), it can also be associated with untreated hyperthyroidism, thus manifesting as a serious complication. This study aims to report the case of a 39-year-old hyperthyroid female patient who developed pancytopenia during hospitalization. Data were collected by means of the medical record, an interview conducted with the patient, and literature review. The patient was admitted to a hospital in Salvador presenting lower extremity edema that progressively evolved to anasarca within 45 days prior to the interview. She also presented weight loss, paroxysmal nocturnal dyspnea, tachycardia, sweating, chills, and laboratory test results for pancytopenia. The case reported here demonstrates an atypical and rare manifestation of hyperthyroidism that improved after the beginning of the treatment, reaching the euthyroid state.Los cambios hematológicos como anemia o pancitopenia pueden ocurrir como manifestaciones atípicas de hipertiroidismo. Aunque la mayoría de los casos de pancitopenia en la enfermedad de Graves se deben al uso de fármacos antitiroideos (tionamidas), también se puede asociar a um hipertiroidismo no tratado y, por tanto, puede manifestarse como una complicación grave. Este estudio tiene como objetivo reportar el caso de una paciente con hipertiroidismo que desarrolló durante la hospitalización pancitopenia secundaria a la enfermedad primaria. La información se obtuvo revisando la historia clínica, entrevistando a la paciente y revisando la literatura. Se trata de una paciente de 39 años ingresada en un hospital de Salvador por presentar edema en miembros inferiores, evolucionando progresivamente a anasarca durante 45 días. Asociado a la afección, presentaba pérdida de peso, disnea paroxística nocturna, taquicardia, sudoración, escalofríos y análisis de laboratorio que mostraban pancitopenia. El caso aquí reportado demuestra una manifestación atípica y rara de hipertiroidismo, que evolucionó luego del inicio del tratamiento y del estado de eutiroidismo.Alterações hematológicas, como anemia ou pancitopenia, podem ser manifestações atípicas do hipertireoidismo. Embora a maioria dos casos de pancitopenia na doença de Graves seja decorrente do uso de drogas antitireoidianas – tionamidas –, ela também pode estar associada ao quadro de hipertireoidismo não tratado e, assim, se manifestar como uma complicação grave. Este estudo tem como objetivo relatar o caso de uma paciente portadora de hipertireoidismo que evoluiu durante o internamento por pancitopenia secundária à doença primária. As informações foram obtidas por meio da revisão do prontuário, entrevista com a paciente e revisão da literatura. Trata-se de uma paciente do sexo feminino, de 39 anos, internada em um hospital de Salvador por apresentar um quadro de edema em membros inferiores que evoluiu progressivamente para anasarca por 45 dias. Associados ao quadro, a paciente apresentava perda ponderal, dispneia paroxística noturna, taquicardia, sudorese e calafrios, além dos exames laboratoriais terem apresentado pancitopenia. O caso relatado demonstra uma manifestação atípica e rara do hipertireoidismo, que melhorou após o início do tratamento e do estado de eutireoidismo.SESAB2021-12-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/355410.22278/2318-2660.2021.v45.nSupl_2.a3554Revista Baiana de Saúde Pública; v. 45 n. supl. 2 (2021); 89-972318-26600100-023310.22278/2318-2660.2021.v45.NSupl_2reponame:Revista Baiana de Saúde Pública (Online)instname:Secretaria da Saúde do Estado da Bahia (Sesab)instacron:IBICTporhttps://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3554/2890Copyright (c) 2021 Revista Baiana de Saúde Públicainfo:eu-repo/semantics/openAccessLucia, Carolina Vitória de Santana, Nina Maia Khouri, Nadia de Andrade 2023-02-13T17:00:34Zoai:ojs.pkp.sfu.ca:article/3554Revistahttps://rbsp.sesab.ba.gov.br/index.php/rbspPUBhttps://rbsp.sesab.ba.gov.br/index.php/rbsp/oai||saude.revista@saude.ba.gov.br|| rbsp.saude@saude.ba.gov.br2318-26600100-0233opendoar:2024-03-06T12:58:21.768090Revista Baiana de Saúde Pública (Online) - Secretaria da Saúde do Estado da Bahia (Sesab)false |
dc.title.none.fl_str_mv |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism Hipoplasia de la médula ósea: manifestación atípica del hipertiroidismo Hipoplasia de medula óssea: manifestação atípica do hipertireoidismo |
title |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism |
spellingShingle |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism Lucia, Carolina Vitória de Hipertireoidismo Pancitopenia Tireotoxicose Hipertireoidismo Pancitopenia Tireotoxicose Hyperthyroidism Pancytopenia Thyrotoxicosis |
title_short |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism |
title_full |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism |
title_fullStr |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism |
title_full_unstemmed |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism |
title_sort |
Bone marrow hypoplasia: atypical manifestation of hyperthyroidism |
author |
Lucia, Carolina Vitória de |
author_facet |
Lucia, Carolina Vitória de Santana, Nina Maia Khouri, Nadia de Andrade |
author_role |
author |
author2 |
Santana, Nina Maia Khouri, Nadia de Andrade |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Lucia, Carolina Vitória de Santana, Nina Maia Khouri, Nadia de Andrade |
dc.subject.por.fl_str_mv |
Hipertireoidismo Pancitopenia Tireotoxicose Hipertireoidismo Pancitopenia Tireotoxicose Hyperthyroidism Pancytopenia Thyrotoxicosis |
topic |
Hipertireoidismo Pancitopenia Tireotoxicose Hipertireoidismo Pancitopenia Tireotoxicose Hyperthyroidism Pancytopenia Thyrotoxicosis |
description |
Hematological changes such as anemia or pancytopenia can occur as atypical manifestations of hyperthyroidism. Although most cases of pancytopenia in Graves’ disease are due to the use of antithyroid drugs (thionamides), it can also be associated with untreated hyperthyroidism, thus manifesting as a serious complication. This study aims to report the case of a 39-year-old hyperthyroid female patient who developed pancytopenia during hospitalization. Data were collected by means of the medical record, an interview conducted with the patient, and literature review. The patient was admitted to a hospital in Salvador presenting lower extremity edema that progressively evolved to anasarca within 45 days prior to the interview. She also presented weight loss, paroxysmal nocturnal dyspnea, tachycardia, sweating, chills, and laboratory test results for pancytopenia. The case reported here demonstrates an atypical and rare manifestation of hyperthyroidism that improved after the beginning of the treatment, reaching the euthyroid state. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12-28 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3554 10.22278/2318-2660.2021.v45.nSupl_2.a3554 |
url |
https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3554 |
identifier_str_mv |
10.22278/2318-2660.2021.v45.nSupl_2.a3554 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3554/2890 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Revista Baiana de Saúde Pública info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 Revista Baiana de Saúde Pública |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
SESAB |
publisher.none.fl_str_mv |
SESAB |
dc.source.none.fl_str_mv |
Revista Baiana de Saúde Pública; v. 45 n. supl. 2 (2021); 89-97 2318-2660 0100-0233 10.22278/2318-2660.2021.v45.NSupl_2 reponame:Revista Baiana de Saúde Pública (Online) instname:Secretaria da Saúde do Estado da Bahia (Sesab) instacron:IBICT |
instname_str |
Secretaria da Saúde do Estado da Bahia (Sesab) |
instacron_str |
IBICT |
institution |
IBICT |
reponame_str |
Revista Baiana de Saúde Pública (Online) |
collection |
Revista Baiana de Saúde Pública (Online) |
repository.name.fl_str_mv |
Revista Baiana de Saúde Pública (Online) - Secretaria da Saúde do Estado da Bahia (Sesab) |
repository.mail.fl_str_mv |
||saude.revista@saude.ba.gov.br|| rbsp.saude@saude.ba.gov.br |
_version_ |
1798948058207092736 |