Recent immunization against measles does not interfere with the sero-response to yellow fever vaccine

• Autor(a) principal: Stefano, Isabel
• Data de Publicação: 1999
• Outros Autores: Sato, Helena K, Pannuti, Claudio S, Omoto, Tereza M, Mann, George, Freire, Marcos S, Yamamura, Anna M. Y, Vasconcelos, Pedro Fernando da Costa, Oselka, Gabriel W, Weckx, Lilly W, Salgado, Maria F, Noale, Lucelene F. O, Souza, Vanda A. U. F
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
• Texto Completo: https://patua.iec.gov.br/handle/iec/1006
• topic: Vacina contra Sarampo / farmacologia; Vacina contra Febre Amarela / farmacologia; Elemento de Resposta Sérica

In order to determine whether previous measles vaccination interferes with the sero-response to yellow fever vaccine, 294 children at nine months of age were randomly assigned to immunization with yellow fever vaccine at di erent time intervals after measles vaccination. The seroconversion rate (SCR) and the log10 geometric mean titer (GMT) for 17 DD yellow fever vaccine at di erent intervals after Schwarz measles vaccination were: 1±6 days: SCR= 44/57= 77%; GMT= 4.57; 7±13 days: SCR= 36/53= 68%; GMT= 4.46; 14±21 days: SCR= 55/65= 85%; GMT= 4.46; 22±27 days: SCR= 41/54= 76%; GMT= 4.41 and >28 days: SCR= 52/65= 80%; GMT= 4.24 ( p> 0.05). We conclude that recent immunization against measles does not interfere with the sero-response to yellow fever vaccine.