Postmortem findings for 7 neonates with congenital Zika Virus Infection

Detalhes bibliográficos
Autor(a) principal: Sousa, Anastácio Q.
Data de Publicação: 2017
Outros Autores: Cavalcante, Diane I. M., Franco, Luciano M., Araújo, Fernanda Montenegro de Carvalho, Sousa, Emília T, Valença Junior, José Telmo, Rolin, Dionne B, Melo, Maria E. L, Sindeaux, Pedro D. T, Araújo, Marialva Tereza Ferreira de, Pearson, Richard D, Wilson, Mary E, Pompeu, Margarida M. L
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/2888
Resumo: Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.
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spelling Sousa, Anastácio Q.Cavalcante, Diane I. M.Franco, Luciano M.Araújo, Fernanda Montenegro de CarvalhoSousa, Emília TValença Junior, José TelmoRolin, Dionne BMelo, Maria E. LSindeaux, Pedro D. TAraújo, Marialva Tereza Ferreira dePearson, Richard DWilson, Mary EPompeu, Margarida M. L2017-11-28T17:25:05Z2017-11-28T17:25:05Z2017SOUSA, Anastácio Q. et al. Postmortem findings for 7 neonates with congenital Zika Virus Infection. Emerging Infectious Diseases, v. 23, n. 7, p. 1164-1167, July 2017.1080-6040https://patua.iec.gov.br/handle/iec/288810.3201/eid2307.162019Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.Federal University of Ceará. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.Ceará State Central Public Health Laboratory. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.University of Fortaleza. Fortaleza, CE, Brazil / Ceará State Secretariat of Health. Fortaleza, CE, Brazil.Ceará State Central Public Health Laboratory. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.University of Virginia School of Medicine. Charlottesville, VA, USA.Chan School of Public Health. Harvard T.H. Boston, MA, USA / University of California, San Francisco. CA, USA.Federal University of Ceará. Fortaleza, CE, Brazil.engCenters for Disease Control and PreventionPostmortem findings for 7 neonates with congenital Zika Virus Infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInfecção pelo Zika virus / congênitoInfecção pelo Zika virus / embriologiaInfecção pelo Zika virus / patologiaInfecção pelo Zika virus / virologiaMicrocefalia / embriologiaMicrocefalia / virologiaAnormalidades Congênitas / virologiaMortalidade Neonatal PrecoceReação em Cadeia da Polimerase Via Transcriptase Reversa / métodosBrasil / epidemiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdfPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdfapplication/pdf2792575https://patua.iec.gov.br/bitstreams/16ac427e-eb49-46c7-8ea4-9fbe27304a33/download8fe65be86c1c9a6ea66224d0f927d78fMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/7ffff110-2a8a-45c2-93ed-5944730e6620/download52f1732ea66fbd1123abe39f5373b797MD52TEXTPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.txtPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.txtExtracted texttext/plain17790https://patua.iec.gov.br/bitstreams/41b31ae1-2e34-4501-9412-87e790584a8b/download2c258cc52aeab2bb1658039604eb00a1MD55THUMBNAILPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.jpgPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.jpgGenerated Thumbnailimage/jpeg6316https://patua.iec.gov.br/bitstreams/6c47697c-8335-4289-a980-81a88ee35044/download2e93c8808a57bad102c5bfa3a63cd2e5MD56iec/28882022-10-20 22:56:04.377oai:patua.iec.gov.br:iec/2888https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T22:56:04Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4=
dc.title.pt_BR.fl_str_mv Postmortem findings for 7 neonates with congenital Zika Virus Infection
title Postmortem findings for 7 neonates with congenital Zika Virus Infection
spellingShingle Postmortem findings for 7 neonates with congenital Zika Virus Infection
Sousa, Anastácio Q.
Infecção pelo Zika virus / congênito
Infecção pelo Zika virus / embriologia
Infecção pelo Zika virus / patologia
Infecção pelo Zika virus / virologia
Microcefalia / embriologia
Microcefalia / virologia
Anormalidades Congênitas / virologia
Mortalidade Neonatal Precoce
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Brasil / epidemiologia
title_short Postmortem findings for 7 neonates with congenital Zika Virus Infection
title_full Postmortem findings for 7 neonates with congenital Zika Virus Infection
title_fullStr Postmortem findings for 7 neonates with congenital Zika Virus Infection
title_full_unstemmed Postmortem findings for 7 neonates with congenital Zika Virus Infection
title_sort Postmortem findings for 7 neonates with congenital Zika Virus Infection
author Sousa, Anastácio Q.
author_facet Sousa, Anastácio Q.
Cavalcante, Diane I. M.
Franco, Luciano M.
Araújo, Fernanda Montenegro de Carvalho
Sousa, Emília T
Valença Junior, José Telmo
Rolin, Dionne B
Melo, Maria E. L
Sindeaux, Pedro D. T
Araújo, Marialva Tereza Ferreira de
Pearson, Richard D
Wilson, Mary E
Pompeu, Margarida M. L
author_role author
author2 Cavalcante, Diane I. M.
Franco, Luciano M.
Araújo, Fernanda Montenegro de Carvalho
Sousa, Emília T
Valença Junior, José Telmo
Rolin, Dionne B
Melo, Maria E. L
Sindeaux, Pedro D. T
Araújo, Marialva Tereza Ferreira de
Pearson, Richard D
Wilson, Mary E
Pompeu, Margarida M. L
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa, Anastácio Q.
Cavalcante, Diane I. M.
Franco, Luciano M.
Araújo, Fernanda Montenegro de Carvalho
Sousa, Emília T
Valença Junior, José Telmo
Rolin, Dionne B
Melo, Maria E. L
Sindeaux, Pedro D. T
Araújo, Marialva Tereza Ferreira de
Pearson, Richard D
Wilson, Mary E
Pompeu, Margarida M. L
dc.subject.decsPrimary.pt_BR.fl_str_mv Infecção pelo Zika virus / congênito
Infecção pelo Zika virus / embriologia
Infecção pelo Zika virus / patologia
Infecção pelo Zika virus / virologia
Microcefalia / embriologia
Microcefalia / virologia
Anormalidades Congênitas / virologia
Mortalidade Neonatal Precoce
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Brasil / epidemiologia
topic Infecção pelo Zika virus / congênito
Infecção pelo Zika virus / embriologia
Infecção pelo Zika virus / patologia
Infecção pelo Zika virus / virologia
Microcefalia / embriologia
Microcefalia / virologia
Anormalidades Congênitas / virologia
Mortalidade Neonatal Precoce
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Brasil / epidemiologia
description Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-11-28T17:25:05Z
dc.date.available.fl_str_mv 2017-11-28T17:25:05Z
dc.date.issued.fl_str_mv 2017
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv SOUSA, Anastácio Q. et al. Postmortem findings for 7 neonates with congenital Zika Virus Infection. Emerging Infectious Diseases, v. 23, n. 7, p. 1164-1167, July 2017.
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/2888
dc.identifier.issn.-.fl_str_mv 1080-6040
dc.identifier.doi.-.fl_str_mv 10.3201/eid2307.162019
identifier_str_mv SOUSA, Anastácio Q. et al. Postmortem findings for 7 neonates with congenital Zika Virus Infection. Emerging Infectious Diseases, v. 23, n. 7, p. 1164-1167, July 2017.
1080-6040
10.3201/eid2307.162019
url https://patua.iec.gov.br/handle/iec/2888
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