Postmortem findings for 7 neonates with congenital Zika Virus Infection
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
| Texto Completo: | https://patua.iec.gov.br/handle/iec/2888 |
Resumo: | Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection. |
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Sousa, Anastácio Q.Cavalcante, Diane I. M.Franco, Luciano M.Araújo, Fernanda Montenegro de CarvalhoSousa, Emília TValença Junior, José TelmoRolin, Dionne BMelo, Maria E. LSindeaux, Pedro D. TAraújo, Marialva Tereza Ferreira dePearson, Richard DWilson, Mary EPompeu, Margarida M. L2017-11-28T17:25:05Z2017-11-28T17:25:05Z2017SOUSA, Anastácio Q. et al. Postmortem findings for 7 neonates with congenital Zika Virus Infection. Emerging Infectious Diseases, v. 23, n. 7, p. 1164-1167, July 2017.1080-6040https://patua.iec.gov.br/handle/iec/288810.3201/eid2307.162019Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.Federal University of Ceará. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.Ceará State Central Public Health Laboratory. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil / Serviço de Verificação de Óbitos. Fortaleza, CE, Brazil.University of Fortaleza. Fortaleza, CE, Brazil / Ceará State Secretariat of Health. Fortaleza, CE, Brazil.Ceará State Central Public Health Laboratory. Fortaleza, CE, Brazil.Federal University of Ceará. Fortaleza, CE, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.University of Virginia School of Medicine. Charlottesville, VA, USA.Chan School of Public Health. Harvard T.H. Boston, MA, USA / University of California, San Francisco. CA, USA.Federal University of Ceará. Fortaleza, CE, Brazil.engCenters for Disease Control and PreventionPostmortem findings for 7 neonates with congenital Zika Virus Infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInfecção pelo Zika virus / congênitoInfecção pelo Zika virus / embriologiaInfecção pelo Zika virus / patologiaInfecção pelo Zika virus / virologiaMicrocefalia / embriologiaMicrocefalia / virologiaAnormalidades Congênitas / virologiaMortalidade Neonatal PrecoceReação em Cadeia da Polimerase Via Transcriptase Reversa / métodosBrasil / epidemiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdfPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdfapplication/pdf2792575https://patua.iec.gov.br/bitstreams/16ac427e-eb49-46c7-8ea4-9fbe27304a33/download8fe65be86c1c9a6ea66224d0f927d78fMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/7ffff110-2a8a-45c2-93ed-5944730e6620/download52f1732ea66fbd1123abe39f5373b797MD52TEXTPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.txtPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.txtExtracted texttext/plain17790https://patua.iec.gov.br/bitstreams/41b31ae1-2e34-4501-9412-87e790584a8b/download2c258cc52aeab2bb1658039604eb00a1MD55THUMBNAILPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.jpgPostmortem findings for 7 neonates with congenital Zika Virus Infection.pdf.jpgGenerated Thumbnailimage/jpeg6316https://patua.iec.gov.br/bitstreams/6c47697c-8335-4289-a980-81a88ee35044/download2e93c8808a57bad102c5bfa3a63cd2e5MD56iec/28882022-10-20 22:56:04.377oai:patua.iec.gov.br:iec/2888https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T22:56:04Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4= |
| dc.title.pt_BR.fl_str_mv |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| title |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| spellingShingle |
Postmortem findings for 7 neonates with congenital Zika Virus Infection Sousa, Anastácio Q. Infecção pelo Zika virus / congênito Infecção pelo Zika virus / embriologia Infecção pelo Zika virus / patologia Infecção pelo Zika virus / virologia Microcefalia / embriologia Microcefalia / virologia Anormalidades Congênitas / virologia Mortalidade Neonatal Precoce Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos Brasil / epidemiologia |
| title_short |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| title_full |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| title_fullStr |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| title_full_unstemmed |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| title_sort |
Postmortem findings for 7 neonates with congenital Zika Virus Infection |
| author |
Sousa, Anastácio Q. |
| author_facet |
Sousa, Anastácio Q. Cavalcante, Diane I. M. Franco, Luciano M. Araújo, Fernanda Montenegro de Carvalho Sousa, Emília T Valença Junior, José Telmo Rolin, Dionne B Melo, Maria E. L Sindeaux, Pedro D. T Araújo, Marialva Tereza Ferreira de Pearson, Richard D Wilson, Mary E Pompeu, Margarida M. L |
| author_role |
author |
| author2 |
Cavalcante, Diane I. M. Franco, Luciano M. Araújo, Fernanda Montenegro de Carvalho Sousa, Emília T Valença Junior, José Telmo Rolin, Dionne B Melo, Maria E. L Sindeaux, Pedro D. T Araújo, Marialva Tereza Ferreira de Pearson, Richard D Wilson, Mary E Pompeu, Margarida M. L |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Sousa, Anastácio Q. Cavalcante, Diane I. M. Franco, Luciano M. Araújo, Fernanda Montenegro de Carvalho Sousa, Emília T Valença Junior, José Telmo Rolin, Dionne B Melo, Maria E. L Sindeaux, Pedro D. T Araújo, Marialva Tereza Ferreira de Pearson, Richard D Wilson, Mary E Pompeu, Margarida M. L |
| dc.subject.decsPrimary.pt_BR.fl_str_mv |
Infecção pelo Zika virus / congênito Infecção pelo Zika virus / embriologia Infecção pelo Zika virus / patologia Infecção pelo Zika virus / virologia Microcefalia / embriologia Microcefalia / virologia Anormalidades Congênitas / virologia Mortalidade Neonatal Precoce Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos Brasil / epidemiologia |
| topic |
Infecção pelo Zika virus / congênito Infecção pelo Zika virus / embriologia Infecção pelo Zika virus / patologia Infecção pelo Zika virus / virologia Microcefalia / embriologia Microcefalia / virologia Anormalidades Congênitas / virologia Mortalidade Neonatal Precoce Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos Brasil / epidemiologia |
| description |
Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection. |
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2017 |
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2017-11-28T17:25:05Z |
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2017-11-28T17:25:05Z |
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2017 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.citation.fl_str_mv |
SOUSA, Anastácio Q. et al. Postmortem findings for 7 neonates with congenital Zika Virus Infection. Emerging Infectious Diseases, v. 23, n. 7, p. 1164-1167, July 2017. |
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https://patua.iec.gov.br/handle/iec/2888 |
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1080-6040 |
| dc.identifier.doi.-.fl_str_mv |
10.3201/eid2307.162019 |
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SOUSA, Anastácio Q. et al. Postmortem findings for 7 neonates with congenital Zika Virus Infection. Emerging Infectious Diseases, v. 23, n. 7, p. 1164-1167, July 2017. 1080-6040 10.3201/eid2307.162019 |
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Centers for Disease Control and Prevention |
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Centers for Disease Control and Prevention |
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