High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/6848 |
Resumo: | Introduction: Although fewer children have been affected by the severe form of the coronavirus disease 2019 (COVID-19), community-acquired pneumonia (CAP) continues to be the leading global cause of child hospitalizations and deaths. Aim: This study investigated the incidence of respiratory syncytial virus (RSV) as well its subtypes (RSV A and B), adenovirus (ADV), rhinovirus (HRV), metapneumovirus (HMPV), coronavirus (NL63, OC43, 229E and HKU1), parainfluenza virus subtypes (PI1, PI2 and PI3), bocavirus and influenza A and B viruses (FluA and FluB) in children diagnosed with CAP during the COVID-19 pandemic. Methods: A total of 200 children with clinically confirmed CAP were initially recruited, of whom 107 had negative qPCR results for SARS-CoV-2 and were included in this study. Viral subtypes were identified using a real-time polymerase chain reaction in the nasopharyngeal swab samples. Results: Viruses were identified in 69.2% of the patients. RSV infections were the most frequently identified (65.4%), with type RSV B being the most prevalent (63.5%). In addition, HCoV 229E and HRV were detected in 6.5% and 3.7% of the patients, respectively. RSV type B was associated with severe acute respiratory infection (ARI) and a younger age (less than 24 months). Conclusions: New strategies for preventing and treating viral respiratory infections, particularly RSV infections, are necessary. |
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Fontes, ValériaFerreira, HivyllaRibeiro, MarilenePinheiro, AruanãMaramaldo, CarlosPereira, EduardoBatista, LuísJúnior, AntonioLobato, LuisSilva, FabianoSousa, LuisLima, WashingtonLima, ClaudiaSoczek, SuzanyCarvalho, RafaelSantos, Mirleide Cordeiro dosFernandes, ElizabethSousa, EduardoNeto, Lidio2023-07-17T17:59:30Z2023-07-17T17:59:30Z2023FONTES, Valéria et al. High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region. Viruses, v. 15, n. 6, 2023. DOI: https://doi.org/10.3390/v15061306. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305439/pdf/viruses-15-01306.pdf.1999-4915https://patua.iec.gov.br/handle/iec/684810.3390/v15061306Introduction: Although fewer children have been affected by the severe form of the coronavirus disease 2019 (COVID-19), community-acquired pneumonia (CAP) continues to be the leading global cause of child hospitalizations and deaths. Aim: This study investigated the incidence of respiratory syncytial virus (RSV) as well its subtypes (RSV A and B), adenovirus (ADV), rhinovirus (HRV), metapneumovirus (HMPV), coronavirus (NL63, OC43, 229E and HKU1), parainfluenza virus subtypes (PI1, PI2 and PI3), bocavirus and influenza A and B viruses (FluA and FluB) in children diagnosed with CAP during the COVID-19 pandemic. Methods: A total of 200 children with clinically confirmed CAP were initially recruited, of whom 107 had negative qPCR results for SARS-CoV-2 and were included in this study. Viral subtypes were identified using a real-time polymerase chain reaction in the nasopharyngeal swab samples. Results: Viruses were identified in 69.2% of the patients. RSV infections were the most frequently identified (65.4%), with type RSV B being the most prevalent (63.5%). In addition, HCoV 229E and HRV were detected in 6.5% and 3.7% of the patients, respectively. RSV type B was associated with severe acute respiratory infection (ARI) and a younger age (less than 24 months). Conclusions: New strategies for preventing and treating viral respiratory infections, particularly RSV infections, are necessary.CEUMA University. Post-Graduate Programme in Microbial Biology. Laboratory of Virology. São Luís, MA, Brazil.Osvaldo Cruz Institute. Central Public Health Laboratory of Maranhão. São Luís, MA, Brazil.Hospital of Federal University of Maranhão. São Luís, MA, Brazil.CEUMA University. Postdoctoral Program in Microbial Biology. São Luís, MA, Brazil.Osvaldo Cruz Institute. Central Public Health Laboratory of Maranhão. São Luís, MA, Brazil.CEUMA University. Post-Graduate Programme in Microbial Biology. Laboratory of Virology. São Luís, MA, Brazil.Federal University of Maranhão. Postgraduate Program in Adult Health. São Luís, MA, Brazil.Federal University of Maranhão. Postgraduate Program in Adult Health. São Luís, MA, Brazil.Osvaldo Cruz Institute. Central Public Health Laboratory of Maranhão. São Luís, MA, Brazil / Oswaldo Cruz Foundation. Post-Graduate Programme in Tropical Medicine. Rio de Janeiro, RJ, Brazil.Osvaldo Cruz Institute. Central Public Health Laboratory of Maranhão. São Luís, MA, Brazil / Oswaldo Cruz Foundation. Post-Graduate Programme in Tropical Medicine. Rio de Janeiro, RJ, Brazil.CEUMA University. Post-Graduate Programme in Microbial Biology. Laboratory of Virology. São Luís, MA, Brazil / Osvaldo Cruz Institute. Central Public Health Laboratory of Maranhão. São Luís, MA, Brazil.CEUMA University. Post-Graduate Programme in Biodiversity and Biotechnology. São Luís, MA, Brazil.CEUMA University. Post-Graduate Programme in Microbial Biology. Laboratory of Virology. São Luís, MA, Brazil.Pelé Pequeno Príncipe Research Institute. Post-Graduate Programme in Biotechnology Applied to Child and Adolescent Health. Curitiba, PR, Brazil.Federal University of Maranhão. Postgraduate Program in Adult Health. São Luís, MA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Pelé Pequeno Príncipe Research Institute. Post-Graduate Programme in Biotechnology Applied to Child and Adolescent Health. Curitiba, PR, Brazil.CEUMA University. Post-Graduate Programme in Microbial Biology. Laboratory of Virology. São Luís, MA, Brazil / Federal University of Maranhão. Postgraduate Program in Adult Health. São Luís, MA, Brazil.CEUMA University. Post-Graduate Programme in Microbial Biology. Laboratory of Virology. São Luís, MA, Brazil / Osvaldo Cruz Institute. Central Public Health Laboratory of Maranhão. São Luís, MA, Brazil / CEUMA University. Post-Graduate Programme in Biodiversity and Biotechnology. São Luís, MA, Brazil.engMDPIHigh incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Regioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInfecções Respiratórias / virologiaInfecções por Vírus Respiratório SincicialVírus Sincicial Respiratório Humanoinfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALHigh Incidence of Respiratory Syncytial Virus in Children with CommunityAcquired Pneumonia from a City in the Brazilian PreAmazon Region.pdfHigh Incidence of Respiratory Syncytial Virus in Children with CommunityAcquired Pneumonia from a City in the Brazilian PreAmazon Region.pdfapplication/pdf551726https://patua.iec.gov.br/bitstreams/0c40822c-50bf-457a-8731-caa3ec8216ed/download3af8795e1ce24bfacb16c5ea06640efcMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/71e66420-e1f1-4d56-abc4-271086207297/download11832eea31b16df8613079d742d61793MD52TEXTHigh Incidence of Respiratory Syncytial Virus in Children with CommunityAcquired Pneumonia from a City in the Brazilian PreAmazon Region.pdf.txtHigh Incidence of Respiratory Syncytial Virus in Children with CommunityAcquired Pneumonia from a City in the Brazilian PreAmazon Region.pdf.txtExtracted texttext/plain47968https://patua.iec.gov.br/bitstreams/1442d221-f003-4174-b520-e80d474baba5/downloadc10d5362936d97b5e86443b2b12529d4MD53THUMBNAILHigh Incidence of Respiratory Syncytial Virus in Children with CommunityAcquired Pneumonia from a City in the Brazilian PreAmazon Region.pdf.jpgHigh Incidence of Respiratory Syncytial Virus in Children with CommunityAcquired Pneumonia from a City in the Brazilian PreAmazon Region.pdf.jpgGenerated Thumbnailimage/jpeg5709https://patua.iec.gov.br/bitstreams/f4067e7d-a34e-46da-8c7d-d8d867021ea0/download6cdc2758099b901057109b5582dcfa7fMD54iec/68482023-07-17 18:27:52.884oai:patua.iec.gov.br:iec/6848https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2023-07-17T18:27:52Repositório Digital do Instituto Evandro Chagas (Patuá) - 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dc.title.pt_BR.fl_str_mv |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
title |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
spellingShingle |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region Fontes, Valéria Infecções Respiratórias / virologia Infecções por Vírus Respiratório Sincicial Vírus Sincicial Respiratório Humano |
title_short |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
title_full |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
title_fullStr |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
title_full_unstemmed |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
title_sort |
High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region |
author |
Fontes, Valéria |
author_facet |
Fontes, Valéria Ferreira, Hivylla Ribeiro, Marilene Pinheiro, Aruanã Maramaldo, Carlos Pereira, Eduardo Batista, Luís Júnior, Antonio Lobato, Luis Silva, Fabiano Sousa, Luis Lima, Washington Lima, Claudia Soczek, Suzany Carvalho, Rafael Santos, Mirleide Cordeiro dos Fernandes, Elizabeth Sousa, Eduardo Neto, Lidio |
author_role |
author |
author2 |
Ferreira, Hivylla Ribeiro, Marilene Pinheiro, Aruanã Maramaldo, Carlos Pereira, Eduardo Batista, Luís Júnior, Antonio Lobato, Luis Silva, Fabiano Sousa, Luis Lima, Washington Lima, Claudia Soczek, Suzany Carvalho, Rafael Santos, Mirleide Cordeiro dos Fernandes, Elizabeth Sousa, Eduardo Neto, Lidio |
author2_role |
author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fontes, Valéria Ferreira, Hivylla Ribeiro, Marilene Pinheiro, Aruanã Maramaldo, Carlos Pereira, Eduardo Batista, Luís Júnior, Antonio Lobato, Luis Silva, Fabiano Sousa, Luis Lima, Washington Lima, Claudia Soczek, Suzany Carvalho, Rafael Santos, Mirleide Cordeiro dos Fernandes, Elizabeth Sousa, Eduardo Neto, Lidio |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Infecções Respiratórias / virologia Infecções por Vírus Respiratório Sincicial Vírus Sincicial Respiratório Humano |
topic |
Infecções Respiratórias / virologia Infecções por Vírus Respiratório Sincicial Vírus Sincicial Respiratório Humano |
description |
Introduction: Although fewer children have been affected by the severe form of the coronavirus disease 2019 (COVID-19), community-acquired pneumonia (CAP) continues to be the leading global cause of child hospitalizations and deaths. Aim: This study investigated the incidence of respiratory syncytial virus (RSV) as well its subtypes (RSV A and B), adenovirus (ADV), rhinovirus (HRV), metapneumovirus (HMPV), coronavirus (NL63, OC43, 229E and HKU1), parainfluenza virus subtypes (PI1, PI2 and PI3), bocavirus and influenza A and B viruses (FluA and FluB) in children diagnosed with CAP during the COVID-19 pandemic. Methods: A total of 200 children with clinically confirmed CAP were initially recruited, of whom 107 had negative qPCR results for SARS-CoV-2 and were included in this study. Viral subtypes were identified using a real-time polymerase chain reaction in the nasopharyngeal swab samples. Results: Viruses were identified in 69.2% of the patients. RSV infections were the most frequently identified (65.4%), with type RSV B being the most prevalent (63.5%). In addition, HCoV 229E and HRV were detected in 6.5% and 3.7% of the patients, respectively. RSV type B was associated with severe acute respiratory infection (ARI) and a younger age (less than 24 months). Conclusions: New strategies for preventing and treating viral respiratory infections, particularly RSV infections, are necessary. |
publishDate |
2023 |
dc.date.accessioned.fl_str_mv |
2023-07-17T17:59:30Z |
dc.date.available.fl_str_mv |
2023-07-17T17:59:30Z |
dc.date.issued.fl_str_mv |
2023 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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dc.identifier.citation.fl_str_mv |
FONTES, Valéria et al. High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region. Viruses, v. 15, n. 6, 2023. DOI: https://doi.org/10.3390/v15061306. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305439/pdf/viruses-15-01306.pdf. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/6848 |
dc.identifier.issn.-.fl_str_mv |
1999-4915 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.3390/v15061306 |
identifier_str_mv |
FONTES, Valéria et al. High incidence of respiratory syncytial virus in children with community-acquired pneumonia from a city in the Brazilian Pre-Amazon Region. Viruses, v. 15, n. 6, 2023. DOI: https://doi.org/10.3390/v15061306. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305439/pdf/viruses-15-01306.pdf. 1999-4915 10.3390/v15061306 |
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https://patua.iec.gov.br/handle/iec/6848 |
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MDPI |
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