Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study

Detalhes bibliográficos
Autor(a) principal: Gusmão, Rosa Helena P
Data de Publicação: 1995
Outros Autores: Mascarenhas, Joana D'Arc Pereira, Gabbay, Yvone Benchimol, Lins-Lainson, Zéa Constante, Ramos, Francisco Lúzio de Paula, Monteiro, Talita Antônia Furtado, Valente, Sebastião Aldo da Silva, Linhares, Alexandre da Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: http://patua.iec.gov.br//handle/iec/3216
Resumo: Faecal samples were obtained from 190 children. aged 0 to 5 years, admitted to a public hospital in Belém. Pará, Brazil. These patients were placed in a pediatric ward with 40 beds distributed in six rooms. Cases were classified into three groups: (a) nosocomial: children who developed gastroenteritis 72 hr or later after admission; (b) community-acquired: patients admitted either with diarrhoea or who had diarrhoea within 72 hr following admission; (c) non-diarrhoeic: those children who had no diarrhoea three days before and three days after collection of formed faecal sample. Specimenswere routinely processed for the presence of rotaviruses. bacteria and parasites. Rotaviruses were detected through enzyme-linked immunosorbent assay (EUSA) and subsequently serotyped/electrophoretyped. Rotaviruses were the most prevalent enteropathogens among nosocomial cases, accounting for 39% (9/23) of diarrhoeal episodes; on the other hand. rotaviruses occurred in 8.3% (11/133) and 9% (3/34) of community-acquired and non-diarrhoeic categories. respectively. Mixed infections involving rotavirus and Giardia intestinalis and rotavirus plus G. intestinalis and Entamoeba histolytica were detected in frequencies of8.6 and4.3%. respectively, in the nosocomial group. The absence of bacterial pathogens in this category, and the unusual low prevalence of these agents in the other two groups may reflect the early and routine administration of antibiotics following admission to this hospital. Rotavirus serotype 2 prevailed over the other types, accounting for 77.8% of isolates from nosocomial diarrhoeal episodes. ln addition, at least five different genomic profiles could be observed, of which one displayed an unusual five-segment first RNA cluster: Dehydration was recorded in all cases of hospital-acquired, rotavirus-associated diarrhoea, whereas in only 57% of nosocomial cases of other aetiology. lt was also noted that nosocomial, rotavirus-associated diarrhoeal episodes occur earlier (7 days), following admission, if compared with those hospital-acquired cases of other aetiology (14 days)
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spelling Gusmão, Rosa Helena PMascarenhas, Joana D'Arc PereiraGabbay, Yvone BenchimolLins-Lainson, Zéa ConstanteRamos, Francisco Lúzio de PaulaMonteiro, Talita Antônia FurtadoValente, Sebastião Aldo da SilvaLinhares, Alexandre da Costa2018-07-12T17:29:26Z2018-07-12T17:29:26Z1995GUSMÃO, Rosa Helena P. et al. Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study. Memórias do Instituto Oswaldo Cruz, v. 90, n. 6, p. 743-749, Nov./Dec. 1995.0074-0276http://patua.iec.gov.br//handle/iec/3216Faecal samples were obtained from 190 children. aged 0 to 5 years, admitted to a public hospital in Belém. Pará, Brazil. These patients were placed in a pediatric ward with 40 beds distributed in six rooms. Cases were classified into three groups: (a) nosocomial: children who developed gastroenteritis 72 hr or later after admission; (b) community-acquired: patients admitted either with diarrhoea or who had diarrhoea within 72 hr following admission; (c) non-diarrhoeic: those children who had no diarrhoea three days before and three days after collection of formed faecal sample. Specimenswere routinely processed for the presence of rotaviruses. bacteria and parasites. Rotaviruses were detected through enzyme-linked immunosorbent assay (EUSA) and subsequently serotyped/electrophoretyped. Rotaviruses were the most prevalent enteropathogens among nosocomial cases, accounting for 39% (9/23) of diarrhoeal episodes; on the other hand. rotaviruses occurred in 8.3% (11/133) and 9% (3/34) of community-acquired and non-diarrhoeic categories. respectively. Mixed infections involving rotavirus and Giardia intestinalis and rotavirus plus G. intestinalis and Entamoeba histolytica were detected in frequencies of8.6 and4.3%. respectively, in the nosocomial group. The absence of bacterial pathogens in this category, and the unusual low prevalence of these agents in the other two groups may reflect the early and routine administration of antibiotics following admission to this hospital. Rotavirus serotype 2 prevailed over the other types, accounting for 77.8% of isolates from nosocomial diarrhoeal episodes. ln addition, at least five different genomic profiles could be observed, of which one displayed an unusual five-segment first RNA cluster: Dehydration was recorded in all cases of hospital-acquired, rotavirus-associated diarrhoea, whereas in only 57% of nosocomial cases of other aetiology. lt was also noted that nosocomial, rotavirus-associated diarrhoeal episodes occur earlier (7 days), following admission, if compared with those hospital-acquired cases of other aetiology (14 days)This work was supported by "Instituto Evandro Chagas, Fundação Nacional de Saúde" and "Conselho Nacional de Desenvolvimento Científico e Tecnológico"Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil..Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.engInstituto Oswaldo CruzRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInfecções por Rotavirus / complicaçõesInfecções por Rotavirus / fisiopatologiaInfecção Hospitalar / diagnósticoInfecção Hospitalar / etiologiaControle de InfecçõesDiarreia Infantil / patologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study.pdfRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study.pdfapplication/pdf1266956https://patua.iec.gov.br/bitstreams/124d8b4e-e929-43f5-98f2-e95be4ad141d/download808d6db190e4c72375e1887bb02d9edbMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/9d6997e1-7c79-4b3b-a3ee-aebddfaeb652/download52f1732ea66fbd1123abe39f5373b797MD52TEXTRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study.pdf.txtRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study.pdf.txtExtracted texttext/plain26977https://patua.iec.gov.br/bitstreams/87bd2f29-74cc-40a5-b431-bf92cdeecbe5/downloade8b1ec2186f9c6d6913800f4da7d84efMD55THUMBNAILRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study.pdf.jpgRotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study.pdf.jpgGenerated Thumbnailimage/jpeg7079https://patua.iec.gov.br/bitstreams/9cacbbe4-34ba-419f-baf4-1be8db0b5957/downloadd802ec3a385cf913c4b27d4a38b6e811MD56iec/32162022-10-20 23:44:21.905oai:patua.iec.gov.br:iec/3216https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T23:44:21Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4=
dc.title.pt_BR.fl_str_mv Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
title Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
spellingShingle Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
Gusmão, Rosa Helena P
Infecções por Rotavirus / complicações
Infecções por Rotavirus / fisiopatologia
Infecção Hospitalar / diagnóstico
Infecção Hospitalar / etiologia
Controle de Infecções
Diarreia Infantil / patologia
title_short Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
title_full Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
title_fullStr Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
title_full_unstemmed Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
title_sort Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study
author Gusmão, Rosa Helena P
author_facet Gusmão, Rosa Helena P
Mascarenhas, Joana D'Arc Pereira
Gabbay, Yvone Benchimol
Lins-Lainson, Zéa Constante
Ramos, Francisco Lúzio de Paula
Monteiro, Talita Antônia Furtado
Valente, Sebastião Aldo da Silva
Linhares, Alexandre da Costa
author_role author
author2 Mascarenhas, Joana D'Arc Pereira
Gabbay, Yvone Benchimol
Lins-Lainson, Zéa Constante
Ramos, Francisco Lúzio de Paula
Monteiro, Talita Antônia Furtado
Valente, Sebastião Aldo da Silva
Linhares, Alexandre da Costa
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gusmão, Rosa Helena P
Mascarenhas, Joana D'Arc Pereira
Gabbay, Yvone Benchimol
Lins-Lainson, Zéa Constante
Ramos, Francisco Lúzio de Paula
Monteiro, Talita Antônia Furtado
Valente, Sebastião Aldo da Silva
Linhares, Alexandre da Costa
dc.subject.decsPrimary.pt_BR.fl_str_mv Infecções por Rotavirus / complicações
Infecções por Rotavirus / fisiopatologia
Infecção Hospitalar / diagnóstico
Infecção Hospitalar / etiologia
Controle de Infecções
Diarreia Infantil / patologia
topic Infecções por Rotavirus / complicações
Infecções por Rotavirus / fisiopatologia
Infecção Hospitalar / diagnóstico
Infecção Hospitalar / etiologia
Controle de Infecções
Diarreia Infantil / patologia
description Faecal samples were obtained from 190 children. aged 0 to 5 years, admitted to a public hospital in Belém. Pará, Brazil. These patients were placed in a pediatric ward with 40 beds distributed in six rooms. Cases were classified into three groups: (a) nosocomial: children who developed gastroenteritis 72 hr or later after admission; (b) community-acquired: patients admitted either with diarrhoea or who had diarrhoea within 72 hr following admission; (c) non-diarrhoeic: those children who had no diarrhoea three days before and three days after collection of formed faecal sample. Specimenswere routinely processed for the presence of rotaviruses. bacteria and parasites. Rotaviruses were detected through enzyme-linked immunosorbent assay (EUSA) and subsequently serotyped/electrophoretyped. Rotaviruses were the most prevalent enteropathogens among nosocomial cases, accounting for 39% (9/23) of diarrhoeal episodes; on the other hand. rotaviruses occurred in 8.3% (11/133) and 9% (3/34) of community-acquired and non-diarrhoeic categories. respectively. Mixed infections involving rotavirus and Giardia intestinalis and rotavirus plus G. intestinalis and Entamoeba histolytica were detected in frequencies of8.6 and4.3%. respectively, in the nosocomial group. The absence of bacterial pathogens in this category, and the unusual low prevalence of these agents in the other two groups may reflect the early and routine administration of antibiotics following admission to this hospital. Rotavirus serotype 2 prevailed over the other types, accounting for 77.8% of isolates from nosocomial diarrhoeal episodes. ln addition, at least five different genomic profiles could be observed, of which one displayed an unusual five-segment first RNA cluster: Dehydration was recorded in all cases of hospital-acquired, rotavirus-associated diarrhoea, whereas in only 57% of nosocomial cases of other aetiology. lt was also noted that nosocomial, rotavirus-associated diarrhoeal episodes occur earlier (7 days), following admission, if compared with those hospital-acquired cases of other aetiology (14 days)
publishDate 1995
dc.date.issued.fl_str_mv 1995
dc.date.accessioned.fl_str_mv 2018-07-12T17:29:26Z
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dc.identifier.citation.fl_str_mv GUSMÃO, Rosa Helena P. et al. Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study. Memórias do Instituto Oswaldo Cruz, v. 90, n. 6, p. 743-749, Nov./Dec. 1995.
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identifier_str_mv GUSMÃO, Rosa Helena P. et al. Rotaviruses as a cause of nosocomial, infantile diarrhoea in Northern Brazil: pilot study. Memórias do Instituto Oswaldo Cruz, v. 90, n. 6, p. 743-749, Nov./Dec. 1995.
0074-0276
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