The effect of three different pulp capping cements on mineralization of dental pulp stem cells

Detalhes bibliográficos
Autor(a) principal: Petta, Thais de Mendonça
Data de Publicação: 2020
Outros Autores: Pedroni, Ana Carla Fagundes, Saavedra, Daniela Feitosa, Faial, Kelson do Carmo Freitas, Marques, Márcia Martins, Couto, Roberta Souza D'Almeida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/4086
Resumo: This study evaluated the osteogenic differentiation of human dental pulp stem cells in response to substances released by the pulp capping agents, Biodentine (BD), mineral trioxide aggregate (MTA) and two-paste calcium hydroxide cement (CHC), along with their physicochemical characteristics. The dimensional stability test showed that of the materials studied, only BD met the standards recommended by the International Organization for Standardization (ISO) for pulp capping materials and thus can be used safely. In the chemical tests, BD was the most stable material. In the Alizarin red S test, BD formed the higher amount of mineralized nodules in the mineralizing medium and also formed mineralized nodules in a non-mineralizing medium. BD releases substances that can significantly induce formation of the human dental pulp stem cell-mineralized extracellular matrix, with physicochemical characteristics that are more conducive to pulp repair than those of MTA and CHC
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spelling Petta, Thais de MendonçaPedroni, Ana Carla FagundesSaavedra, Daniela FeitosaFaial, Kelson do Carmo FreitasMarques, Márcia MartinsCouto, Roberta Souza D'Almeida2020-04-29T16:30:03Z2020-04-29T16:30:03Z2020PETTA, Thais de Mendonça et al. The effect of three different pulp capping cements on mineralization of dental pulp stem cells. Dental Materials Journal, v. 39, n, 2, p. 222-228, 2020.1881-1361https://patua.iec.gov.br/handle/iec/408610.4012/dmj.2018-349This study evaluated the osteogenic differentiation of human dental pulp stem cells in response to substances released by the pulp capping agents, Biodentine (BD), mineral trioxide aggregate (MTA) and two-paste calcium hydroxide cement (CHC), along with their physicochemical characteristics. The dimensional stability test showed that of the materials studied, only BD met the standards recommended by the International Organization for Standardization (ISO) for pulp capping materials and thus can be used safely. In the chemical tests, BD was the most stable material. In the Alizarin red S test, BD formed the higher amount of mineralized nodules in the mineralizing medium and also formed mineralized nodules in a non-mineralizing medium. BD releases substances that can significantly induce formation of the human dental pulp stem cell-mineralized extracellular matrix, with physicochemical characteristics that are more conducive to pulp repair than those of MTA and CHCCAPES and PROPESP/UFPAFederal University of Pará. School of Dentistry. Departament of Dentistry. Belém, PA, Brazil.University of São Paulo. School of Dentistry. Departament of Dentistry. São Paulo, SP, Brazil.Federal University of Pará. School of Dentistry. Departament of Dentistry. Belém, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.University of São Paulo. School of Dentistry. Departament of Dentistry. São Paulo, SP, Brazil.Federal University of Pará. School of Dentistry. Departament of Dentistry. Belém, PA, Brazil.engJ-STAGEThe effect of three different pulp capping cements on mineralization of dental pulp stem cellsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleOsteogênesePolpa Dentária / anatomia & histologiaCapeamento da Polpa Dentária / métodosCimentos Dentários / uso terapêuticoPulpectomia / métodosinfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALThe effect of three different pulp capping cements on mineralization of dental pulp stem cells.pdfThe effect of three different pulp capping cements on mineralization of dental pulp stem cells.pdfapplication/pdf2148495https://patua.iec.gov.br/bitstreams/e677d3fc-0303-4246-9a45-12faab8f322c/downloadc5c9e19ff4c627d3cbcfce4fbcf764ddMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/deb10ddb-8b65-4aff-bb6a-ac52b3b16193/download11832eea31b16df8613079d742d61793MD52TEXTThe effect of three different pulp capping cements on mineralization of dental pulp stem cells.pdf.txtThe effect of three different pulp capping cements on mineralization of dental pulp stem cells.pdf.txtExtracted texttext/plain25653https://patua.iec.gov.br/bitstreams/2627e673-ff10-4533-abc7-12325d1a878c/download33d2922019c5889aacba3df718e5504bMD55THUMBNAILThe effect of three different pulp capping cements on mineralization of dental pulp stem cells.pdf.jpgThe effect of three different pulp capping cements on mineralization of dental pulp stem cells.pdf.jpgGenerated Thumbnailimage/jpeg5848https://patua.iec.gov.br/bitstreams/e1d46c50-8ee3-4f10-a67e-29f43fb7a9e0/downloaded68f5e33be4b2248128aabe58b61618MD56iec/40862022-10-20 23:44:37.334oai:patua.iec.gov.br:iec/4086https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T23:44:37Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)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
dc.title.pt_BR.fl_str_mv The effect of three different pulp capping cements on mineralization of dental pulp stem cells
title The effect of three different pulp capping cements on mineralization of dental pulp stem cells
spellingShingle The effect of three different pulp capping cements on mineralization of dental pulp stem cells
Petta, Thais de Mendonça
Osteogênese
Polpa Dentária / anatomia & histologia
Capeamento da Polpa Dentária / métodos
Cimentos Dentários / uso terapêutico
Pulpectomia / métodos
title_short The effect of three different pulp capping cements on mineralization of dental pulp stem cells
title_full The effect of three different pulp capping cements on mineralization of dental pulp stem cells
title_fullStr The effect of three different pulp capping cements on mineralization of dental pulp stem cells
title_full_unstemmed The effect of three different pulp capping cements on mineralization of dental pulp stem cells
title_sort The effect of three different pulp capping cements on mineralization of dental pulp stem cells
author Petta, Thais de Mendonça
author_facet Petta, Thais de Mendonça
Pedroni, Ana Carla Fagundes
Saavedra, Daniela Feitosa
Faial, Kelson do Carmo Freitas
Marques, Márcia Martins
Couto, Roberta Souza D'Almeida
author_role author
author2 Pedroni, Ana Carla Fagundes
Saavedra, Daniela Feitosa
Faial, Kelson do Carmo Freitas
Marques, Márcia Martins
Couto, Roberta Souza D'Almeida
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Petta, Thais de Mendonça
Pedroni, Ana Carla Fagundes
Saavedra, Daniela Feitosa
Faial, Kelson do Carmo Freitas
Marques, Márcia Martins
Couto, Roberta Souza D'Almeida
dc.subject.decsPrimary.pt_BR.fl_str_mv Osteogênese
Polpa Dentária / anatomia & histologia
Capeamento da Polpa Dentária / métodos
Cimentos Dentários / uso terapêutico
Pulpectomia / métodos
topic Osteogênese
Polpa Dentária / anatomia & histologia
Capeamento da Polpa Dentária / métodos
Cimentos Dentários / uso terapêutico
Pulpectomia / métodos
description This study evaluated the osteogenic differentiation of human dental pulp stem cells in response to substances released by the pulp capping agents, Biodentine (BD), mineral trioxide aggregate (MTA) and two-paste calcium hydroxide cement (CHC), along with their physicochemical characteristics. The dimensional stability test showed that of the materials studied, only BD met the standards recommended by the International Organization for Standardization (ISO) for pulp capping materials and thus can be used safely. In the chemical tests, BD was the most stable material. In the Alizarin red S test, BD formed the higher amount of mineralized nodules in the mineralizing medium and also formed mineralized nodules in a non-mineralizing medium. BD releases substances that can significantly induce formation of the human dental pulp stem cell-mineralized extracellular matrix, with physicochemical characteristics that are more conducive to pulp repair than those of MTA and CHC
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-04-29T16:30:03Z
dc.date.available.fl_str_mv 2020-04-29T16:30:03Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv PETTA, Thais de Mendonça et al. The effect of three different pulp capping cements on mineralization of dental pulp stem cells. Dental Materials Journal, v. 39, n, 2, p. 222-228, 2020.
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/4086
dc.identifier.issn.-.fl_str_mv 1881-1361
dc.identifier.doi.-.fl_str_mv 10.4012/dmj.2018-349
identifier_str_mv PETTA, Thais de Mendonça et al. The effect of three different pulp capping cements on mineralization of dental pulp stem cells. Dental Materials Journal, v. 39, n, 2, p. 222-228, 2020.
1881-1361
10.4012/dmj.2018-349
url https://patua.iec.gov.br/handle/iec/4086
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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instname:Instituto Evandro Chagas (IEC)
instacron:IEC
instname_str Instituto Evandro Chagas (IEC)
instacron_str IEC
institution IEC
reponame_str Repositório Digital do Instituto Evandro Chagas (Patuá)
collection Repositório Digital do Instituto Evandro Chagas (Patuá)
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