Venezuelan equine encephalitis virus infection of cotton rats

Detalhes bibliográficos
Autor(a) principal: Carrara, Anne-Sophie
Data de Publicação: 2007
Outros Autores: Coffey, Lark L, Aguilar, Patricia V, Moncayo, Abelardo C, Rosa, Amélia Paes de Andrade Travassos da, Nunes, Márcio Roberto Teixeira, Tesh, Robert B, Weaver, Scott C
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/1004
Resumo: Venezuelan equine encephalitis virus (VEEV) is an emerging pathogen of equids and humans, but infection of its rodent reservoir hosts has received little study. To determine whether responses to infection vary among geographic populations, we inoculated 3 populations of cotton rats with 2 enzootic VEEV strains (Co97-0054 [enzootic ID subtype] and 68U201 [enzootic IE subtype]). The 3 populations were offspring from wild-caught cotton rats collected in a VEE-enzootic area of south Florida, USA; wild-caught cotton rats from a non–VEE-enzootic area of Texas, USA; and commercially available (Harlan) colony-reared cotton rats from a non–VEE-enzootic region. Although each population had similar early viremia titers, no detectable disease developed in the VEE-sympatric Florida animals, but severe disease and death affected the Texas and Harlan animals. Our fi ndings suggest that the geographic origins of cotton rats are important determinants of the outcome of VEE infection and reservoir potential of these rodents.
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spelling Carrara, Anne-SophieCoffey, Lark LAguilar, Patricia VMoncayo, Abelardo CRosa, Amélia Paes de Andrade Travassos daNunes, Márcio Roberto TeixeiraTesh, Robert BWeaver, Scott C2016-01-26T11:40:27Z2016-01-26T11:40:27Z2007CARRARA, Anne-Sophie et al. Venezuelan equine encephalitis virus infection of cotton rats. Emerging Infectious Diseases, v. 13, n. 8, p. 1158-1165, Aug. 2007. DOI: https://doi.org/10.3201/eid1308.061157. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828070/pdf/06-1157_finalR.pdf.1080-6040https://patua.iec.gov.br/handle/iec/100410.3201/eid1308.061157Venezuelan equine encephalitis virus (VEEV) is an emerging pathogen of equids and humans, but infection of its rodent reservoir hosts has received little study. To determine whether responses to infection vary among geographic populations, we inoculated 3 populations of cotton rats with 2 enzootic VEEV strains (Co97-0054 [enzootic ID subtype] and 68U201 [enzootic IE subtype]). The 3 populations were offspring from wild-caught cotton rats collected in a VEE-enzootic area of south Florida, USA; wild-caught cotton rats from a non–VEE-enzootic area of Texas, USA; and commercially available (Harlan) colony-reared cotton rats from a non–VEE-enzootic region. Although each population had similar early viremia titers, no detectable disease developed in the VEE-sympatric Florida animals, but severe disease and death affected the Texas and Harlan animals. Our fi ndings suggest that the geographic origins of cotton rats are important determinants of the outcome of VEE infection and reservoir potential of these rodents.University of Texas Medical Branch. Galveston, TX, USA.University of Texas Medical Branch. Galveston, TX, USA.University of Texas Medical Branch. Galveston, TX, USA.University of Texas Medical Branch. Galveston, TX, USA.University of Texas Medical Branch. Galveston, TX, USA.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.University of Texas Medical Branch. Galveston, TX, USA.University of Texas Medical Branch. 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dc.title.pt_BR.fl_str_mv Venezuelan equine encephalitis virus infection of cotton rats
title Venezuelan equine encephalitis virus infection of cotton rats
spellingShingle Venezuelan equine encephalitis virus infection of cotton rats
Carrara, Anne-Sophie
Encefalomielite Eqüina Venezuelana / epidemiologia
Encefalomielite Eqüina Venezuelana / transmissão
Sigmodontinae / virologia
Togaviridae
Alphavirus
Encefalite por Arbovirus / epidemiologia
Encefalite por Arbovirus / transmissão
Florida (USA)
Texas (USA)
title_short Venezuelan equine encephalitis virus infection of cotton rats
title_full Venezuelan equine encephalitis virus infection of cotton rats
title_fullStr Venezuelan equine encephalitis virus infection of cotton rats
title_full_unstemmed Venezuelan equine encephalitis virus infection of cotton rats
title_sort Venezuelan equine encephalitis virus infection of cotton rats
author Carrara, Anne-Sophie
author_facet Carrara, Anne-Sophie
Coffey, Lark L
Aguilar, Patricia V
Moncayo, Abelardo C
Rosa, Amélia Paes de Andrade Travassos da
Nunes, Márcio Roberto Teixeira
Tesh, Robert B
Weaver, Scott C
author_role author
author2 Coffey, Lark L
Aguilar, Patricia V
Moncayo, Abelardo C
Rosa, Amélia Paes de Andrade Travassos da
Nunes, Márcio Roberto Teixeira
Tesh, Robert B
Weaver, Scott C
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carrara, Anne-Sophie
Coffey, Lark L
Aguilar, Patricia V
Moncayo, Abelardo C
Rosa, Amélia Paes de Andrade Travassos da
Nunes, Márcio Roberto Teixeira
Tesh, Robert B
Weaver, Scott C
dc.subject.decsPrimary.pt_BR.fl_str_mv Encefalomielite Eqüina Venezuelana / epidemiologia
Encefalomielite Eqüina Venezuelana / transmissão
Sigmodontinae / virologia
Togaviridae
Alphavirus
Encefalite por Arbovirus / epidemiologia
Encefalite por Arbovirus / transmissão
Florida (USA)
Texas (USA)
topic Encefalomielite Eqüina Venezuelana / epidemiologia
Encefalomielite Eqüina Venezuelana / transmissão
Sigmodontinae / virologia
Togaviridae
Alphavirus
Encefalite por Arbovirus / epidemiologia
Encefalite por Arbovirus / transmissão
Florida (USA)
Texas (USA)
description Venezuelan equine encephalitis virus (VEEV) is an emerging pathogen of equids and humans, but infection of its rodent reservoir hosts has received little study. To determine whether responses to infection vary among geographic populations, we inoculated 3 populations of cotton rats with 2 enzootic VEEV strains (Co97-0054 [enzootic ID subtype] and 68U201 [enzootic IE subtype]). The 3 populations were offspring from wild-caught cotton rats collected in a VEE-enzootic area of south Florida, USA; wild-caught cotton rats from a non–VEE-enzootic area of Texas, USA; and commercially available (Harlan) colony-reared cotton rats from a non–VEE-enzootic region. Although each population had similar early viremia titers, no detectable disease developed in the VEE-sympatric Florida animals, but severe disease and death affected the Texas and Harlan animals. Our fi ndings suggest that the geographic origins of cotton rats are important determinants of the outcome of VEE infection and reservoir potential of these rodents.
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2016-01-26T11:40:27Z
dc.date.available.fl_str_mv 2016-01-26T11:40:27Z
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dc.identifier.citation.fl_str_mv CARRARA, Anne-Sophie et al. Venezuelan equine encephalitis virus infection of cotton rats. Emerging Infectious Diseases, v. 13, n. 8, p. 1158-1165, Aug. 2007. DOI: https://doi.org/10.3201/eid1308.061157. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828070/pdf/06-1157_finalR.pdf.
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/1004
dc.identifier.issn.-.fl_str_mv 1080-6040
dc.identifier.doi.pt_BR.fl_str_mv 10.3201/eid1308.061157
identifier_str_mv CARRARA, Anne-Sophie et al. Venezuelan equine encephalitis virus infection of cotton rats. Emerging Infectious Diseases, v. 13, n. 8, p. 1158-1165, Aug. 2007. DOI: https://doi.org/10.3201/eid1308.061157. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828070/pdf/06-1157_finalR.pdf.
1080-6040
10.3201/eid1308.061157
url https://patua.iec.gov.br/handle/iec/1004
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publisher.none.fl_str_mv Centers for Disease Control and Prevention
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