Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease

Detalhes bibliográficos
Autor(a) principal: Bittencourt, A. L
Data de Publicação: 1985
Outros Autores: Mota, E, Póvoa, Marinete Marins
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/695
Resumo: The isoenzyme profiles of a group of tive Trypanosoma cruzi stocks obtained from congenital cases and of a second group of seven stocks obtained from chagasic mothers who did not transmit their infection congenitally were studied by electrophoresis of nine enzymes. All the mothers became infected in Bahia State (Brazil). With the exception ora triple 'heterozygous' GPI pattern, all T. cruzi stocks were identified as zymodeme 2 (Z2). The heterozygous pattern has not been recorded previously in Bahia. This study shows that enzymically similar T. cruzi stocks can show different behaviour with respect to transplacental transmission, and also with respect to clinicopathological presentation and therapeutic response of the congenital cases.
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spelling Bittencourt, A. LMota, EPóvoa, Marinete Marins2016-01-26T11:36:41Z2016-01-26T11:36:41Z1985BITTENCOURT, A. L.; MOTA, E.; PÓVOA, Marinete Marins. Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease. Annals of Tropical Medicine and Parasitology, v. 79, n. 4, p. 393-396, 1985.0003-4983https://patua.iec.gov.br/handle/iec/695The isoenzyme profiles of a group of tive Trypanosoma cruzi stocks obtained from congenital cases and of a second group of seven stocks obtained from chagasic mothers who did not transmit their infection congenitally were studied by electrophoresis of nine enzymes. All the mothers became infected in Bahia State (Brazil). With the exception ora triple 'heterozygous' GPI pattern, all T. cruzi stocks were identified as zymodeme 2 (Z2). The heterozygous pattern has not been recorded previously in Bahia. This study shows that enzymically similar T. cruzi stocks can show different behaviour with respect to transplacental transmission, and also with respect to clinicopathological presentation and therapeutic response of the congenital cases.Federal University of Bahia. School for Medicine. Departament of Pathology and Departament of Preventive Medicine. Bahia, BA, Brazil.Federal University of Bahia. School for Medicine. Departament of Pathology and Departament of Preventive Medicine. Bahia, BA, Brazil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.application/pdfengTaylor & FrancisIsoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDoença de Chagas / transmissãoDoença de Chagas / congênitoDoença de Chagas / parasitologiaIsoenzimasTrypanosoma cruzi / enzimologiaComplicações na GravidezHeterozigotoEletroforeseinfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALIsoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease .pdfapplication/pdf678247https://patua.iec.gov.br/bitstreams/8ccfb16b-8b36-4fd5-b03b-3871a5375167/downloadbde85230c29e550d463a5060b75b2752MD51TEXTfile_1.pdf.txtfile_1.pdf.txtExtracted texttext/plain14620https://patua.iec.gov.br/bitstreams/79964f52-a2cb-4a43-8c5d-04f2bf16afd4/downloadcb236d0f0a00166d956ebf52af2fb1c7MD52Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease .pdf.txtIsoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease .pdf.txtExtracted texttext/plain14738https://patua.iec.gov.br/bitstreams/f5258d61-db6d-498e-8914-37f8ffcbcc32/downloada76923b1540e9b3b794a7e3c58ded781MD57THUMBNAILfile_1.pdf.jpgfile_1.pdf.jpgIM Thumbnailimage/jpeg4828https://patua.iec.gov.br/bitstreams/7281b226-1829-4713-a2d3-c9094bdb4179/downloadf7e81b56aa9f277deea0075e9ee3095bMD53Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease .pdf.jpgIsoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease .pdf.jpgGenerated Thumbnailimage/jpeg6509https://patua.iec.gov.br/bitstreams/8a7acd1f-dd3a-4397-a96d-af7cc5e5f998/download363db73ee187a49222f82372c032dbfaMD58LICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
title Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
spellingShingle Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
Bittencourt, A. L
Doença de Chagas / transmissão
Doença de Chagas / congênito
Doença de Chagas / parasitologia
Isoenzimas
Trypanosoma cruzi / enzimologia
Complicações na Gravidez
Heterozigoto
Eletroforese
title_short Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
title_full Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
title_fullStr Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
title_full_unstemmed Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
title_sort Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease
author Bittencourt, A. L
author_facet Bittencourt, A. L
Mota, E
Póvoa, Marinete Marins
author_role author
author2 Mota, E
Póvoa, Marinete Marins
author2_role author
author
dc.contributor.author.fl_str_mv Bittencourt, A. L
Mota, E
Póvoa, Marinete Marins
dc.subject.decsPrimary.pt_BR.fl_str_mv Doença de Chagas / transmissão
Doença de Chagas / congênito
Doença de Chagas / parasitologia
Isoenzimas
Trypanosoma cruzi / enzimologia
Complicações na Gravidez
Heterozigoto
Eletroforese
topic Doença de Chagas / transmissão
Doença de Chagas / congênito
Doença de Chagas / parasitologia
Isoenzimas
Trypanosoma cruzi / enzimologia
Complicações na Gravidez
Heterozigoto
Eletroforese
description The isoenzyme profiles of a group of tive Trypanosoma cruzi stocks obtained from congenital cases and of a second group of seven stocks obtained from chagasic mothers who did not transmit their infection congenitally were studied by electrophoresis of nine enzymes. All the mothers became infected in Bahia State (Brazil). With the exception ora triple 'heterozygous' GPI pattern, all T. cruzi stocks were identified as zymodeme 2 (Z2). The heterozygous pattern has not been recorded previously in Bahia. This study shows that enzymically similar T. cruzi stocks can show different behaviour with respect to transplacental transmission, and also with respect to clinicopathological presentation and therapeutic response of the congenital cases.
publishDate 1985
dc.date.issued.fl_str_mv 1985
dc.date.accessioned.fl_str_mv 2016-01-26T11:36:41Z
dc.date.available.fl_str_mv 2016-01-26T11:36:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv BITTENCOURT, A. L.; MOTA, E.; PÓVOA, Marinete Marins. Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease. Annals of Tropical Medicine and Parasitology, v. 79, n. 4, p. 393-396, 1985.
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/695
dc.identifier.issn.-.fl_str_mv 0003-4983
identifier_str_mv BITTENCOURT, A. L.; MOTA, E.; PÓVOA, Marinete Marins. Isoenzyme characterization of Trypanosoma cruzi from congenital cases of Chagas' disease. Annals of Tropical Medicine and Parasitology, v. 79, n. 4, p. 393-396, 1985.
0003-4983
url https://patua.iec.gov.br/handle/iec/695
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:Repositório Digital do Instituto Evandro Chagas (Patuá)
instname:Instituto Evandro Chagas (IEC)
instacron:IEC
instname_str Instituto Evandro Chagas (IEC)
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institution IEC
reponame_str Repositório Digital do Instituto Evandro Chagas (Patuá)
collection Repositório Digital do Instituto Evandro Chagas (Patuá)
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