Characterization of two new rhabdoviruses isolated from midges (Culicoides SPP) in the Brazilian Amazon: proposed members of a new genus, Bracorhabdovirus

• Autor(a) principal: Diniz Junior, José Antônio Picanço
• Data de Publicação: 2006
• Outros Autores: Nunes, Márcio Roberto Teixeira, Rosa, Amélia Paes de Andrade Travassos da, Cruz, Ana Cecília Ribeiro, Souza, Wanderley de, Medeiros, Daniele Barbosa de Almeida, Chiang, Jannifer Oliveira, Vasconcelos, Pedro Fernando da Costa
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
• Texto Completo: https://patua.iec.gov.br/handle/iec/1003
• topic: Rhabdoviridae / classificação; Rhabdoviridae / isolamento & purificação; Ceratopogonidae / patogenicidade; Ceratopogonidae / virologia; Infecções por Rhabdoviridae; Sorologia / métodos; Ceratopogonidae / virologia; Camundongos; Região Amazônica (BR)

Itacaiunas and Curionopolis viruses were isolated from Culicoides midges in Parauapebas municipality, Para state, Brazil, in 1984 and 1985, respectively. Itacaiunas virus infected newborn mice and mosquito cells (C6/36), but did not replicate in some mammalian cell lineages; while Curionopolis virus infected only mice. Neither virus showed a serological relationship with any of the 195 known arboviruses circulating in Brazil, nor against 38 other rhabdoviruses isolated worldwide. Both virus particles are bullet-shaped and similar in morphology to that observed for other members of the family Rhabdoviridae. Partial nucleotide sequencing of the N protein showed that those two viruses constitute a separate clade in the family Rhabdoviridae, which we propose to be a new genus, designated Bracorhabdovirus