An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings
Autor(a) principal: | |
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Data de Publicação: | 1981 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/2562 |
Resumo: | An outbreak of human illness caused by Mayaro (MA Y) vírus occurred in Belterra, Pará, Brazil in the first half of 1978. A total of 55 cases were confirmed., 43 by vírus isolation and serology, and 12 by serology alone. The disease in Belterra presented as a distinct clinical syndrome characterized by fever, arthralgia and exanthema. No fatalities could be attributed to MA Y vírus infection. Arthralgia, accompanied by joint edema in 20% of cases, was a very prominent sigo which caused temporary incapacity in many patients. Arthralgia was present in virtually ali confirmed cases and persisted in some for at least 2 months, although with decreasing severity. Rash was present in two-thirds of the cases, and was either maculopapular or micropapular. The incidence of rash was higher in children than in adults. Contrary to arthralgia, which started with the onset of clinical illness, rash usually appeared on the 5th day and faded within 3-4 days. Fever, chills, headache, myalgia, lymphadenopathy and other minor clinical manifestations were algo recorded, and generally persisted for from 2-5 days. Leucopenia was a constant finding in alI cases. Mild albuminuria was seen in four of 25 patients, and slight thrombocytopenia was seen in 10 of 20 cases. The fact that viremia levels higher than 5.0 loglJ1.0 ml of blood were recorded in 10 patients raises the possibility that man may be an amplifying host in the MA Y vírus cycle. The MA Y vírus illness, as seen in Belterra, has clínical features similar to those observed ín persons íinfectedwith chikungunya vírus |
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Pinheiro, Francisco de PaulaFreitas, Ronaldo Barros deRosa, Jorge Fernando Soares Travassos daGabbay, Yvone BenchimolMello, Wyller Alencar deLeDuc, James W2017-05-29T14:23:35Z2017-05-29T14:23:35Z1981PINHEIRO, Francisco de Paula et al. An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings. American Journal of Tropical Medicine and Hygiene, v. 30, n. 3, p. 674-681, 1981.0002-9637https://patua.iec.gov.br/handle/iec/2562An outbreak of human illness caused by Mayaro (MA Y) vírus occurred in Belterra, Pará, Brazil in the first half of 1978. A total of 55 cases were confirmed., 43 by vírus isolation and serology, and 12 by serology alone. The disease in Belterra presented as a distinct clinical syndrome characterized by fever, arthralgia and exanthema. No fatalities could be attributed to MA Y vírus infection. Arthralgia, accompanied by joint edema in 20% of cases, was a very prominent sigo which caused temporary incapacity in many patients. Arthralgia was present in virtually ali confirmed cases and persisted in some for at least 2 months, although with decreasing severity. Rash was present in two-thirds of the cases, and was either maculopapular or micropapular. The incidence of rash was higher in children than in adults. Contrary to arthralgia, which started with the onset of clinical illness, rash usually appeared on the 5th day and faded within 3-4 days. Fever, chills, headache, myalgia, lymphadenopathy and other minor clinical manifestations were algo recorded, and generally persisted for from 2-5 days. Leucopenia was a constant finding in alI cases. Mild albuminuria was seen in four of 25 patients, and slight thrombocytopenia was seen in 10 of 20 cases. The fact that viremia levels higher than 5.0 loglJ1.0 ml of blood were recorded in 10 patients raises the possibility that man may be an amplifying host in the MA Y vírus cycle. The MA Y vírus illness, as seen in Belterra, has clínical features similar to those observed ín persons íinfectedwith chikungunya vírusMinistério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.United States Army Medical Research Unit. Belém, PA, Brazil.application/pdfengAmerican Society of Tropical Medicine and HygieneAn outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findingsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAlphavirus / isolamento & purificaçãoSurtos de DoençasInfecções por Togaviridae / epidemiologiaInfecções por Togaviridae / parasitologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECTHUMBNAILAn outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings.pdf.jpgAn outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings.pdf.jpgGenerated Thumbnailimage/jpeg5986https://patua.iec.gov.br/bitstreams/9b8f8575-6360-4bcb-a0c1-23b2afcc3ad1/download92d1caa3e24c399a5492a94dd5a05f1aMD56ORIGINALAn outbreak of Mayaro virus disease in Belterra, Brazil. I. 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dc.title.pt_BR.fl_str_mv |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
title |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
spellingShingle |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings Pinheiro, Francisco de Paula Alphavirus / isolamento & purificação Surtos de Doenças Infecções por Togaviridae / epidemiologia Infecções por Togaviridae / parasitologia |
title_short |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
title_full |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
title_fullStr |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
title_full_unstemmed |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
title_sort |
An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings |
author |
Pinheiro, Francisco de Paula |
author_facet |
Pinheiro, Francisco de Paula Freitas, Ronaldo Barros de Rosa, Jorge Fernando Soares Travassos da Gabbay, Yvone Benchimol Mello, Wyller Alencar de LeDuc, James W |
author_role |
author |
author2 |
Freitas, Ronaldo Barros de Rosa, Jorge Fernando Soares Travassos da Gabbay, Yvone Benchimol Mello, Wyller Alencar de LeDuc, James W |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pinheiro, Francisco de Paula Freitas, Ronaldo Barros de Rosa, Jorge Fernando Soares Travassos da Gabbay, Yvone Benchimol Mello, Wyller Alencar de LeDuc, James W |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Alphavirus / isolamento & purificação Surtos de Doenças Infecções por Togaviridae / epidemiologia Infecções por Togaviridae / parasitologia |
topic |
Alphavirus / isolamento & purificação Surtos de Doenças Infecções por Togaviridae / epidemiologia Infecções por Togaviridae / parasitologia |
description |
An outbreak of human illness caused by Mayaro (MA Y) vírus occurred in Belterra, Pará, Brazil in the first half of 1978. A total of 55 cases were confirmed., 43 by vírus isolation and serology, and 12 by serology alone. The disease in Belterra presented as a distinct clinical syndrome characterized by fever, arthralgia and exanthema. No fatalities could be attributed to MA Y vírus infection. Arthralgia, accompanied by joint edema in 20% of cases, was a very prominent sigo which caused temporary incapacity in many patients. Arthralgia was present in virtually ali confirmed cases and persisted in some for at least 2 months, although with decreasing severity. Rash was present in two-thirds of the cases, and was either maculopapular or micropapular. The incidence of rash was higher in children than in adults. Contrary to arthralgia, which started with the onset of clinical illness, rash usually appeared on the 5th day and faded within 3-4 days. Fever, chills, headache, myalgia, lymphadenopathy and other minor clinical manifestations were algo recorded, and generally persisted for from 2-5 days. Leucopenia was a constant finding in alI cases. Mild albuminuria was seen in four of 25 patients, and slight thrombocytopenia was seen in 10 of 20 cases. The fact that viremia levels higher than 5.0 loglJ1.0 ml of blood were recorded in 10 patients raises the possibility that man may be an amplifying host in the MA Y vírus cycle. The MA Y vírus illness, as seen in Belterra, has clínical features similar to those observed ín persons íinfectedwith chikungunya vírus |
publishDate |
1981 |
dc.date.issued.fl_str_mv |
1981 |
dc.date.accessioned.fl_str_mv |
2017-05-29T14:23:35Z |
dc.date.available.fl_str_mv |
2017-05-29T14:23:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
PINHEIRO, Francisco de Paula et al. An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings. American Journal of Tropical Medicine and Hygiene, v. 30, n. 3, p. 674-681, 1981. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/2562 |
dc.identifier.issn.-.fl_str_mv |
0002-9637 |
identifier_str_mv |
PINHEIRO, Francisco de Paula et al. An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings. American Journal of Tropical Medicine and Hygiene, v. 30, n. 3, p. 674-681, 1981. 0002-9637 |
url |
https://patua.iec.gov.br/handle/iec/2562 |
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eng |
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eng |
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openAccess |
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American Society of Tropical Medicine and Hygiene |
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American Society of Tropical Medicine and Hygiene |
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