Effects of liquid extract from Plinia cauliflora fruits residues on Chinese hamsters biochemical parameters

• Autor(a) principal: Borges,Leonardo Luiz
• Data de Publicação: 2023
• Outros Autores: Martins,Frederico Severino, Franco,João José, Bailão,Elisa Flávia Luiz Cardoso, Cruvinel,Wilson de Melo, Uyemura,Sérgio Akira, Conceição,Edemilson Cardoso da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Biology
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100173
• topic: biochemical parameters; Cerrado; glycemia; jabuticaba; Myrciaria cauliflora; uric acid

Abstract Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. Since hyperuricemia is considered to be a significant risk factor of metabolic disorders and the principal pathological basis of gout, the liquid extract from P. cauliflora fruits residues would be a promising candidate as a novel hypouricaemic agent for further investigation.