Chronic psychological stress and its impact on the development of aggressive breast cancer

Detalhes bibliográficos
Autor(a) principal: Cormanique,Thayse Fachin
Data de Publicação: 2015
Outros Autores: Almeida,Lirane Elize Defante Ferreto de, Rech,Cynthia Alba, Rech,Daniel, Herrera,Ana Cristina da Silva do Amaral, Panis,Carolina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300352
Resumo: Objective To investigate the clinicopathological findings of women diagnosed with breast cancer and study the impact of chronic psychological stress on the pathological characteristics of these tumors.Methods We investigated a cohort composed of women diagnosed with breast cancer and divided into two groups. One group was categorized as presenting with chronic psychological stress (by using the Self-Reporting Questionnaire − SRQ-20). Another group of women with breast cancer, but with no previous history of chronic psychological stress, comprised the Control Group. Clinical and pathological data were assessed.Results Women presenting with a history of chronic distress were significantly overweight when compared to the Control Group. Furthermore, it was observed that these stressed women also had a significant percentage of aggressive breast cancer subtype, the HER2 amplified tumor, which could be putatively associated with the loss of immunosurveillance.Conclusion Our findings suggested an interaction among chronic psychological stress, overweight, and the development of more aggressive breast tumors.
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spelling Chronic psychological stress and its impact on the development of aggressive breast cancerStress, psychologicalBreast neoplasmsOverweightObesityMonitoring, immunologicObjective To investigate the clinicopathological findings of women diagnosed with breast cancer and study the impact of chronic psychological stress on the pathological characteristics of these tumors.Methods We investigated a cohort composed of women diagnosed with breast cancer and divided into two groups. One group was categorized as presenting with chronic psychological stress (by using the Self-Reporting Questionnaire − SRQ-20). Another group of women with breast cancer, but with no previous history of chronic psychological stress, comprised the Control Group. Clinical and pathological data were assessed.Results Women presenting with a history of chronic distress were significantly overweight when compared to the Control Group. Furthermore, it was observed that these stressed women also had a significant percentage of aggressive breast cancer subtype, the HER2 amplified tumor, which could be putatively associated with the loss of immunosurveillance.Conclusion Our findings suggested an interaction among chronic psychological stress, overweight, and the development of more aggressive breast tumors.Instituto Israelita de Ensino e Pesquisa Albert Einstein2015-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300352einstein (São Paulo) v.13 n.3 2015reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/S1679-45082015AO3344info:eu-repo/semantics/openAccessCormanique,Thayse FachinAlmeida,Lirane Elize Defante Ferreto deRech,Cynthia AlbaRech,DanielHerrera,Ana Cristina da Silva do AmaralPanis,Carolinaeng2015-10-13T00:00:00Zoai:scielo:S1679-45082015000300352Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2015-10-13T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Chronic psychological stress and its impact on the development of aggressive breast cancer
title Chronic psychological stress and its impact on the development of aggressive breast cancer
spellingShingle Chronic psychological stress and its impact on the development of aggressive breast cancer
Cormanique,Thayse Fachin
Stress, psychological
Breast neoplasms
Overweight
Obesity
Monitoring, immunologic
title_short Chronic psychological stress and its impact on the development of aggressive breast cancer
title_full Chronic psychological stress and its impact on the development of aggressive breast cancer
title_fullStr Chronic psychological stress and its impact on the development of aggressive breast cancer
title_full_unstemmed Chronic psychological stress and its impact on the development of aggressive breast cancer
title_sort Chronic psychological stress and its impact on the development of aggressive breast cancer
author Cormanique,Thayse Fachin
author_facet Cormanique,Thayse Fachin
Almeida,Lirane Elize Defante Ferreto de
Rech,Cynthia Alba
Rech,Daniel
Herrera,Ana Cristina da Silva do Amaral
Panis,Carolina
author_role author
author2 Almeida,Lirane Elize Defante Ferreto de
Rech,Cynthia Alba
Rech,Daniel
Herrera,Ana Cristina da Silva do Amaral
Panis,Carolina
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cormanique,Thayse Fachin
Almeida,Lirane Elize Defante Ferreto de
Rech,Cynthia Alba
Rech,Daniel
Herrera,Ana Cristina da Silva do Amaral
Panis,Carolina
dc.subject.por.fl_str_mv Stress, psychological
Breast neoplasms
Overweight
Obesity
Monitoring, immunologic
topic Stress, psychological
Breast neoplasms
Overweight
Obesity
Monitoring, immunologic
description Objective To investigate the clinicopathological findings of women diagnosed with breast cancer and study the impact of chronic psychological stress on the pathological characteristics of these tumors.Methods We investigated a cohort composed of women diagnosed with breast cancer and divided into two groups. One group was categorized as presenting with chronic psychological stress (by using the Self-Reporting Questionnaire − SRQ-20). Another group of women with breast cancer, but with no previous history of chronic psychological stress, comprised the Control Group. Clinical and pathological data were assessed.Results Women presenting with a history of chronic distress were significantly overweight when compared to the Control Group. Furthermore, it was observed that these stressed women also had a significant percentage of aggressive breast cancer subtype, the HER2 amplified tumor, which could be putatively associated with the loss of immunosurveillance.Conclusion Our findings suggested an interaction among chronic psychological stress, overweight, and the development of more aggressive breast tumors.
publishDate 2015
dc.date.none.fl_str_mv 2015-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300352
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300352
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1679-45082015AO3344
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.13 n.3 2015
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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