Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000100052 |
Resumo: | ABSTRACT Objective: To verify serum procalcitonin levels of patients with acute respiratory failure secondary to influenza A (H1N1) upon their admission to the Intensive Care Unit and to compare these results to values found in patients with sepsis and trauma admitted to the same unit. Methods: Analysis of records of patients infected with influenza A (H1N1) and respiratory failure admitted to the General Intensive Care Unit during in a period of 60 days. The values of serum procalcitonin and clinical and laboratory data were compared to those of all patients admitted with sepsis or trauma in the previous year. Results: Among patients with influenza A (H1N1) (n = 16), the median serum procalcitonin level upon admission was 0.11 ng/mL, lower than in the sepsis group (p < 0.001) and slightly lower than in trauma patients. Although the mean values were low, serum procalcitonin was a strong predictor of hospital mortality in patients with influenza A (H1N1). Conclusion: Patients with influenza A (H1N1) with severe acute respiratory failure presented with low serum procalcitonin values upon admission, although their serum levels are predictors of hospital mortality. The kinetics study of this biomarker may be a useful tool in the management of this group of patients. |
id |
IIEPAE-1_34a402fb9eb4e4bba12f7e4ce705315c |
---|---|
oai_identifier_str |
oai:scielo:S1679-45082011000100052 |
network_acronym_str |
IIEPAE-1 |
network_name_str |
Einstein (São Paulo) |
repository_id_str |
|
spelling |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failurePneumonia, viralSepsisIntensive care unitsBiomarkers, pharmacologicalCalcitoninInfectionABSTRACT Objective: To verify serum procalcitonin levels of patients with acute respiratory failure secondary to influenza A (H1N1) upon their admission to the Intensive Care Unit and to compare these results to values found in patients with sepsis and trauma admitted to the same unit. Methods: Analysis of records of patients infected with influenza A (H1N1) and respiratory failure admitted to the General Intensive Care Unit during in a period of 60 days. The values of serum procalcitonin and clinical and laboratory data were compared to those of all patients admitted with sepsis or trauma in the previous year. Results: Among patients with influenza A (H1N1) (n = 16), the median serum procalcitonin level upon admission was 0.11 ng/mL, lower than in the sepsis group (p < 0.001) and slightly lower than in trauma patients. Although the mean values were low, serum procalcitonin was a strong predictor of hospital mortality in patients with influenza A (H1N1). Conclusion: Patients with influenza A (H1N1) with severe acute respiratory failure presented with low serum procalcitonin values upon admission, although their serum levels are predictors of hospital mortality. The kinetics study of this biomarker may be a useful tool in the management of this group of patients.Instituto Israelita de Ensino e Pesquisa Albert Einstein2011-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000100052einstein (São Paulo) v.9 n.1 2011reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082011ao1878info:eu-repo/semantics/openAccessDuarte,Péricles Almeida DelfinoBredt,Carla Sakuma de OliveiraBredt Jr,Gerson LuísJorge,Amaury CésarVenazzi,AlissonTondo,Leônidas GustavoOliveira,Luciana Schmidt Cardon deJorge,Marcela MariaMarchiori,RobertaGiancursi,Thiago SimõesCoradin,MarceloAlexandrino,Anderson Gustavoeng2017-03-14T00:00:00Zoai:scielo:S1679-45082011000100052Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-03-14T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
title |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
spellingShingle |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure Duarte,Péricles Almeida Delfino Pneumonia, viral Sepsis Intensive care units Biomarkers, pharmacological Calcitonin Infection |
title_short |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
title_full |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
title_fullStr |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
title_full_unstemmed |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
title_sort |
Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure |
author |
Duarte,Péricles Almeida Delfino |
author_facet |
Duarte,Péricles Almeida Delfino Bredt,Carla Sakuma de Oliveira Bredt Jr,Gerson Luís Jorge,Amaury César Venazzi,Alisson Tondo,Leônidas Gustavo Oliveira,Luciana Schmidt Cardon de Jorge,Marcela Maria Marchiori,Roberta Giancursi,Thiago Simões Coradin,Marcelo Alexandrino,Anderson Gustavo |
author_role |
author |
author2 |
Bredt,Carla Sakuma de Oliveira Bredt Jr,Gerson Luís Jorge,Amaury César Venazzi,Alisson Tondo,Leônidas Gustavo Oliveira,Luciana Schmidt Cardon de Jorge,Marcela Maria Marchiori,Roberta Giancursi,Thiago Simões Coradin,Marcelo Alexandrino,Anderson Gustavo |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Duarte,Péricles Almeida Delfino Bredt,Carla Sakuma de Oliveira Bredt Jr,Gerson Luís Jorge,Amaury César Venazzi,Alisson Tondo,Leônidas Gustavo Oliveira,Luciana Schmidt Cardon de Jorge,Marcela Maria Marchiori,Roberta Giancursi,Thiago Simões Coradin,Marcelo Alexandrino,Anderson Gustavo |
dc.subject.por.fl_str_mv |
Pneumonia, viral Sepsis Intensive care units Biomarkers, pharmacological Calcitonin Infection |
topic |
Pneumonia, viral Sepsis Intensive care units Biomarkers, pharmacological Calcitonin Infection |
description |
ABSTRACT Objective: To verify serum procalcitonin levels of patients with acute respiratory failure secondary to influenza A (H1N1) upon their admission to the Intensive Care Unit and to compare these results to values found in patients with sepsis and trauma admitted to the same unit. Methods: Analysis of records of patients infected with influenza A (H1N1) and respiratory failure admitted to the General Intensive Care Unit during in a period of 60 days. The values of serum procalcitonin and clinical and laboratory data were compared to those of all patients admitted with sepsis or trauma in the previous year. Results: Among patients with influenza A (H1N1) (n = 16), the median serum procalcitonin level upon admission was 0.11 ng/mL, lower than in the sepsis group (p < 0.001) and slightly lower than in trauma patients. Although the mean values were low, serum procalcitonin was a strong predictor of hospital mortality in patients with influenza A (H1N1). Conclusion: Patients with influenza A (H1N1) with severe acute respiratory failure presented with low serum procalcitonin values upon admission, although their serum levels are predictors of hospital mortality. The kinetics study of this biomarker may be a useful tool in the management of this group of patients. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000100052 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000100052 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1679-45082011ao1878 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.9 n.1 2011 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
_version_ |
1752129905912446976 |