Immunoinflammatory mediators in the pathogenesis of diabetes mellitus

Detalhes bibliográficos
Autor(a) principal: Gomes,Bárbara Festa
Data de Publicação: 2019
Outros Autores: Accardo,Camila de Melo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000100600
Resumo: ABSTRACT Characterized as a metabolic syndrome with multiple consequences for the lives of patients, diabetes mellitus is also classified as a chronic non-communicable disease of great scope in the world. It is a complex disease, with different points of view, including the relation between inflammatory process, obesity and insulin resistance due to the performance of the various immunoinflammatory mediators - called adipokines - on glycemic homeostasis. Recent studies have precisely addressed this aspect for the development of drugs that assist in the protection of pancreatic ß cells from the damages arising from oxidative stress and inflammatory process, in order to control the hyperglycemic picture, which is characteristic of diabetes mellitus.
id IIEPAE-1_455020767aca86291f6dee6df27ba533
oai_identifier_str oai:scielo:S1679-45082019000100600
network_acronym_str IIEPAE-1
network_name_str Einstein (São Paulo)
repository_id_str
spelling Immunoinflammatory mediators in the pathogenesis of diabetes mellitusDiabetes mellitusInsulin resistanceAdipokinesObesityABSTRACT Characterized as a metabolic syndrome with multiple consequences for the lives of patients, diabetes mellitus is also classified as a chronic non-communicable disease of great scope in the world. It is a complex disease, with different points of view, including the relation between inflammatory process, obesity and insulin resistance due to the performance of the various immunoinflammatory mediators - called adipokines - on glycemic homeostasis. Recent studies have precisely addressed this aspect for the development of drugs that assist in the protection of pancreatic ß cells from the damages arising from oxidative stress and inflammatory process, in order to control the hyperglycemic picture, which is characteristic of diabetes mellitus.Instituto Israelita de Ensino e Pesquisa Albert Einstein2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000100600einstein (São Paulo) v.17 n.1 2019reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.31744/einstein_journal/2019rb4596info:eu-repo/semantics/openAccessGomes,Bárbara FestaAccardo,Camila de Meloeng2019-02-20T00:00:00Zoai:scielo:S1679-45082019000100600Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2019-02-20T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
title Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
spellingShingle Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
Gomes,Bárbara Festa
Diabetes mellitus
Insulin resistance
Adipokines
Obesity
title_short Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
title_full Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
title_fullStr Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
title_full_unstemmed Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
title_sort Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
author Gomes,Bárbara Festa
author_facet Gomes,Bárbara Festa
Accardo,Camila de Melo
author_role author
author2 Accardo,Camila de Melo
author2_role author
dc.contributor.author.fl_str_mv Gomes,Bárbara Festa
Accardo,Camila de Melo
dc.subject.por.fl_str_mv Diabetes mellitus
Insulin resistance
Adipokines
Obesity
topic Diabetes mellitus
Insulin resistance
Adipokines
Obesity
description ABSTRACT Characterized as a metabolic syndrome with multiple consequences for the lives of patients, diabetes mellitus is also classified as a chronic non-communicable disease of great scope in the world. It is a complex disease, with different points of view, including the relation between inflammatory process, obesity and insulin resistance due to the performance of the various immunoinflammatory mediators - called adipokines - on glycemic homeostasis. Recent studies have precisely addressed this aspect for the development of drugs that assist in the protection of pancreatic ß cells from the damages arising from oxidative stress and inflammatory process, in order to control the hyperglycemic picture, which is characteristic of diabetes mellitus.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000100600
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000100600
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.31744/einstein_journal/2019rb4596
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.17 n.1 2019
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
_version_ 1752129909606580224

Registros relacionados