What is the role of heat shock protein in abdominal organ transplantation?

Detalhes bibliográficos
Autor(a) principal: Calil,Igor Lepski
Data de Publicação: 2022
Outros Autores: Tustumi,Francisco, Sousa,Jorge Henrique Bento de, Tomazini,Bruno Martins, Cruz Jr,Ruy Jorge, Saliba,Gustavo Niankowski, Pécora,Rafael Antonio Arruda, D’Albuquerque,Luiz Augusto Carneiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603
Resumo: ABSTRACT Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes.
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spelling What is the role of heat shock protein in abdominal organ transplantation?Reperfusion injuryHeat-shock proteinsKidney transplantationLiver transplantationOrgan transplantationABSTRACT Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes.Instituto Israelita de Ensino e Pesquisa Albert Einstein2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603einstein (São Paulo) v.20 2022reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.31744/einstein_journal/2022rb6181info:eu-repo/semantics/openAccessCalil,Igor LepskiTustumi,FranciscoSousa,Jorge Henrique Bento deTomazini,Bruno MartinsCruz Jr,Ruy JorgeSaliba,Gustavo NiankowskiPécora,Rafael Antonio ArrudaD’Albuquerque,Luiz Augusto Carneiroeng2022-03-09T00:00:00Zoai:scielo:S1679-45082022000100603Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2022-03-09T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv What is the role of heat shock protein in abdominal organ transplantation?
title What is the role of heat shock protein in abdominal organ transplantation?
spellingShingle What is the role of heat shock protein in abdominal organ transplantation?
Calil,Igor Lepski
Reperfusion injury
Heat-shock proteins
Kidney transplantation
Liver transplantation
Organ transplantation
title_short What is the role of heat shock protein in abdominal organ transplantation?
title_full What is the role of heat shock protein in abdominal organ transplantation?
title_fullStr What is the role of heat shock protein in abdominal organ transplantation?
title_full_unstemmed What is the role of heat shock protein in abdominal organ transplantation?
title_sort What is the role of heat shock protein in abdominal organ transplantation?
author Calil,Igor Lepski
author_facet Calil,Igor Lepski
Tustumi,Francisco
Sousa,Jorge Henrique Bento de
Tomazini,Bruno Martins
Cruz Jr,Ruy Jorge
Saliba,Gustavo Niankowski
Pécora,Rafael Antonio Arruda
D’Albuquerque,Luiz Augusto Carneiro
author_role author
author2 Tustumi,Francisco
Sousa,Jorge Henrique Bento de
Tomazini,Bruno Martins
Cruz Jr,Ruy Jorge
Saliba,Gustavo Niankowski
Pécora,Rafael Antonio Arruda
D’Albuquerque,Luiz Augusto Carneiro
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Calil,Igor Lepski
Tustumi,Francisco
Sousa,Jorge Henrique Bento de
Tomazini,Bruno Martins
Cruz Jr,Ruy Jorge
Saliba,Gustavo Niankowski
Pécora,Rafael Antonio Arruda
D’Albuquerque,Luiz Augusto Carneiro
dc.subject.por.fl_str_mv Reperfusion injury
Heat-shock proteins
Kidney transplantation
Liver transplantation
Organ transplantation
topic Reperfusion injury
Heat-shock proteins
Kidney transplantation
Liver transplantation
Organ transplantation
description ABSTRACT Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.31744/einstein_journal/2022rb6181
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.20 2022
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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