What is the role of heat shock protein in abdominal organ transplantation?
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603 |
Resumo: | ABSTRACT Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes. |
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What is the role of heat shock protein in abdominal organ transplantation?Reperfusion injuryHeat-shock proteinsKidney transplantationLiver transplantationOrgan transplantationABSTRACT Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes.Instituto Israelita de Ensino e Pesquisa Albert Einstein2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603einstein (São Paulo) v.20 2022reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.31744/einstein_journal/2022rb6181info:eu-repo/semantics/openAccessCalil,Igor LepskiTustumi,FranciscoSousa,Jorge Henrique Bento deTomazini,Bruno MartinsCruz Jr,Ruy JorgeSaliba,Gustavo NiankowskiPécora,Rafael Antonio ArrudaD’Albuquerque,Luiz Augusto Carneiroeng2022-03-09T00:00:00Zoai:scielo:S1679-45082022000100603Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2022-03-09T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
What is the role of heat shock protein in abdominal organ transplantation? |
title |
What is the role of heat shock protein in abdominal organ transplantation? |
spellingShingle |
What is the role of heat shock protein in abdominal organ transplantation? Calil,Igor Lepski Reperfusion injury Heat-shock proteins Kidney transplantation Liver transplantation Organ transplantation |
title_short |
What is the role of heat shock protein in abdominal organ transplantation? |
title_full |
What is the role of heat shock protein in abdominal organ transplantation? |
title_fullStr |
What is the role of heat shock protein in abdominal organ transplantation? |
title_full_unstemmed |
What is the role of heat shock protein in abdominal organ transplantation? |
title_sort |
What is the role of heat shock protein in abdominal organ transplantation? |
author |
Calil,Igor Lepski |
author_facet |
Calil,Igor Lepski Tustumi,Francisco Sousa,Jorge Henrique Bento de Tomazini,Bruno Martins Cruz Jr,Ruy Jorge Saliba,Gustavo Niankowski Pécora,Rafael Antonio Arruda D’Albuquerque,Luiz Augusto Carneiro |
author_role |
author |
author2 |
Tustumi,Francisco Sousa,Jorge Henrique Bento de Tomazini,Bruno Martins Cruz Jr,Ruy Jorge Saliba,Gustavo Niankowski Pécora,Rafael Antonio Arruda D’Albuquerque,Luiz Augusto Carneiro |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Calil,Igor Lepski Tustumi,Francisco Sousa,Jorge Henrique Bento de Tomazini,Bruno Martins Cruz Jr,Ruy Jorge Saliba,Gustavo Niankowski Pécora,Rafael Antonio Arruda D’Albuquerque,Luiz Augusto Carneiro |
dc.subject.por.fl_str_mv |
Reperfusion injury Heat-shock proteins Kidney transplantation Liver transplantation Organ transplantation |
topic |
Reperfusion injury Heat-shock proteins Kidney transplantation Liver transplantation Organ transplantation |
description |
ABSTRACT Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100603 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.31744/einstein_journal/2022rb6181 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.20 2022 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
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1752129911332536320 |