Heart transplantation: review

Detalhes bibliográficos
Autor(a) principal: Mangini,Sandrigo
Data de Publicação: 2015
Outros Autores: Alves,Bárbara Rubim, Silvestre,Odílson Marcos, Pires,Philippe Vieira, Pires,Lucas José Tachotti, Curiati,Milena Novaes Cardoso, Bacal,Fernando
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025
Resumo: ABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants.
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spelling Heart transplantation: reviewHeart transplantationHeart transplantation/adverse effectsInfectionsGraft rejectionABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants.Instituto Israelita de Ensino e Pesquisa Albert Einstein2015-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025einstein (São Paulo) v.13 n.2 2015reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/S1679-45082015RW3154info:eu-repo/semantics/openAccessMangini,SandrigoAlves,Bárbara RubimSilvestre,Odílson MarcosPires,Philippe VieiraPires,Lucas José TachottiCuriati,Milena Novaes CardosoBacal,Fernandoeng2015-12-03T00:00:00Zoai:scielo:S1679-45082015000200025Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2015-12-03T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Heart transplantation: review
title Heart transplantation: review
spellingShingle Heart transplantation: review
Mangini,Sandrigo
Heart transplantation
Heart transplantation/adverse effects
Infections
Graft rejection
title_short Heart transplantation: review
title_full Heart transplantation: review
title_fullStr Heart transplantation: review
title_full_unstemmed Heart transplantation: review
title_sort Heart transplantation: review
author Mangini,Sandrigo
author_facet Mangini,Sandrigo
Alves,Bárbara Rubim
Silvestre,Odílson Marcos
Pires,Philippe Vieira
Pires,Lucas José Tachotti
Curiati,Milena Novaes Cardoso
Bacal,Fernando
author_role author
author2 Alves,Bárbara Rubim
Silvestre,Odílson Marcos
Pires,Philippe Vieira
Pires,Lucas José Tachotti
Curiati,Milena Novaes Cardoso
Bacal,Fernando
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mangini,Sandrigo
Alves,Bárbara Rubim
Silvestre,Odílson Marcos
Pires,Philippe Vieira
Pires,Lucas José Tachotti
Curiati,Milena Novaes Cardoso
Bacal,Fernando
dc.subject.por.fl_str_mv Heart transplantation
Heart transplantation/adverse effects
Infections
Graft rejection
topic Heart transplantation
Heart transplantation/adverse effects
Infections
Graft rejection
description ABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1679-45082015RW3154
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.13 n.2 2015
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
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instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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