Heart transplantation: review
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025 |
Resumo: | ABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants. |
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Heart transplantation: reviewHeart transplantationHeart transplantation/adverse effectsInfectionsGraft rejectionABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants.Instituto Israelita de Ensino e Pesquisa Albert Einstein2015-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025einstein (São Paulo) v.13 n.2 2015reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/S1679-45082015RW3154info:eu-repo/semantics/openAccessMangini,SandrigoAlves,Bárbara RubimSilvestre,Odílson MarcosPires,Philippe VieiraPires,Lucas José TachottiCuriati,Milena Novaes CardosoBacal,Fernandoeng2015-12-03T00:00:00Zoai:scielo:S1679-45082015000200025Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2015-12-03T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Heart transplantation: review |
title |
Heart transplantation: review |
spellingShingle |
Heart transplantation: review Mangini,Sandrigo Heart transplantation Heart transplantation/adverse effects Infections Graft rejection |
title_short |
Heart transplantation: review |
title_full |
Heart transplantation: review |
title_fullStr |
Heart transplantation: review |
title_full_unstemmed |
Heart transplantation: review |
title_sort |
Heart transplantation: review |
author |
Mangini,Sandrigo |
author_facet |
Mangini,Sandrigo Alves,Bárbara Rubim Silvestre,Odílson Marcos Pires,Philippe Vieira Pires,Lucas José Tachotti Curiati,Milena Novaes Cardoso Bacal,Fernando |
author_role |
author |
author2 |
Alves,Bárbara Rubim Silvestre,Odílson Marcos Pires,Philippe Vieira Pires,Lucas José Tachotti Curiati,Milena Novaes Cardoso Bacal,Fernando |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Mangini,Sandrigo Alves,Bárbara Rubim Silvestre,Odílson Marcos Pires,Philippe Vieira Pires,Lucas José Tachotti Curiati,Milena Novaes Cardoso Bacal,Fernando |
dc.subject.por.fl_str_mv |
Heart transplantation Heart transplantation/adverse effects Infections Graft rejection |
topic |
Heart transplantation Heart transplantation/adverse effects Infections Graft rejection |
description |
ABSTRACT Heart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, right ventricular dysfunction, rejection, and infections, whereas late complications include cardiac allograft vasculopathy and neoplasms. Despite the difficulties for heart transplantation, in particular, the shortage of donors and high mortality while on the waiting list, in Brazil, there is a great potential for both increasing effective donors and using circulatory assist devices, which can positively impact the number and outcomes of heart transplants. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000200025 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1679-45082015RW3154 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.13 n.2 2015 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
_version_ |
1752129907915227136 |